Competitive Endogenous RNA Landscape in Epstein-Barr Virus Associated Nasopharyngeal Carcinoma [PDF]
Non-coding RNAs have been shown to play important regulatory roles, notably in cancer development. In this study, we investigated the role of microRNAs and circular RNAs in Nasopharyngeal Carcinoma (NPC) by constructing a circRNA-miRNA-mRNA co-expression
Xiandong Lin +7 more
doaj +3 more sources
Establishment of potential lncRNA-related hub genes involved competitive endogenous RNA in lung adenocarcinoma [PDF]
Long non-coding RNAs (lncRNAs) have a notable role in the diagnosis and prognosis of cancer. However, the associations between lncRNA-related hub genes (LRHGs) expression and the corresponding outcomes have not been fully understood in lung ...
Yong Li +6 more
doaj +2 more sources
Long noncoding RNA DHRS4 antisense RNA 1 suppresses osteosarcoma cell proliferation and promotes apoptosis through a competitive endogenous RNA mechanism [PDF]
Osteosarcoma (OS) is the most common primary malignant bone tumor. Recent evidence suggests that the novel long noncoding RNA DHRS4 antisense RNA 1 (DHRS4-AS1) serves an important role in cancer progression and metastasis.
Zhouzhou Tang +5 more
doaj +2 more sources
The Integrative Analysis of Competitive Endogenous RNA Regulatory Networks in Coronary Artery Disease [PDF]
Background: Coronary artery disease (CAD) is the leading cause of cardiovascular death. The competitive endogenous RNAs (ceRNAs) hypothesis is a new theory that explains the relationship between lncRNAs and miRNAs.
Yuyao Ji +7 more
doaj +3 more sources
To identify the prognostic biomarker of the competitive endogenous RNA (ceRNA) and explore the tumor infiltrating immune cells (TIICs) which might be the potential prognostic factors in lung adenocarcinoma.
Wenjie Chen +7 more
doaj +3 more sources
miR-34a regulates phenotypic modulation of vascular smooth muscle cells in intracranial aneurysm by targeting CXCR3 and MMP-2 [PDF]
MicroRNAs (miRNAs) dysregulation is tightly related to diseases including tumor, neuro disease and cardiovascular disease. In this study, we investigated the potential biological effects of miR-34a and its target CXCR3 in phenotypic modulation of ...
Xuesong Yuan +5 more
doaj +1 more source
Advances on the roles of circular RNA in breast cancer [PDF]
Circular RNA (circRNA) is a kind of non-coding RNA with circular structure and is found in a variety of cell types. CircRNA is characterized by diversity, specificity, conservatism and stability.
HE Xiao, HU Wei-jie, LYU Wen-chang, REN Yu-ping, WU Min, WU Yi-ping, ZHANG Qi
doaj +1 more source
Analysis of Competitive Endogenous RNA Regulatory Network of Exosomal Breast Cancer Based on exoRBase [PDF]
Zhu K, Wang Q, Wang L.
exaly +2 more sources
Whole transcriptome sequencing identifies a competitive endogenous RNA network that regulates the immunity of bladder cancer [PDF]
Zhiqiang Dong, Kangli Deng
exaly +2 more sources
Role of competitive endogenous RNA networks in the pathogenesis of coronary artery disease [PDF]
The present study aimed to construct a network of competitive endogenous RNAs (ceRNAs) related to the pathogenesis of coronary artery disease (CAD), to provide a novel rationale for CAD treatment.Bioinformatics methods were applied to screen for differentially expressed long non-coding RNAs (DElncRNAs), microRNAs (DEmiRNAs), and mRNAs (DEmRNAs) from ...
Zuo, Jiebin +4 more
openaire +2 more sources

