Results 11 to 20 of about 4,342,004 (341)
Complement Activation in Kidneys of Patients With COVID-19
Frontiers in Immunology, 2021 Most patients who became critically ill following infection with COVID-19 develop severe acute respiratory syndrome (SARS) attributed to a maladaptive or inadequate immune response.
F. Pfister +10 more
semanticscholar +1 more source
Neurovascular injury with complement activation and inflammation in COVID-19
Brain : a journal of neurology, 2022 The underlying mechanisms by which severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) leads to acute and long-term neurological manifestations remains obscure.
Myoung-Hwa Lee +13 more
semanticscholar +1 more source
Factors affecting IgG4-mediated complement activation
Frontiers in Immunology, 2023 Of the four human immunoglobulin G (IgG) subclasses, IgG4 is considered the least inflammatory, in part because it poorly activates the complement system.
Nienke Oskam +13 more
doaj +1 more source
Nanoparticle-Induced Complement Activation: Implications for Cancer Nanomedicine
Frontiers in Immunology, 2021 Nanoparticle-based anticancer medications were first approved for cancer treatment almost 2 decades ago. Patients benefit from these approaches because of the targeted-drug delivery and reduced toxicity, however, like other therapies, adverse reactions ...
N. M. La‐Beck +2 more
semanticscholar +1 more source
Inside-Out of Complement in Cancer
Frontiers in Immunology, 2022 The role of complement in cancer has received increasing attention over the last decade. Recent studies provide compelling evidence that complement accelerates cancer progression.
Martin Kolev +5 more
doaj +1 more source
Complement Activation Is a Prominent Feature of MOGAD
Annals of Neurology, 2021 Myelin oligodendrocyte glycoprotein (MOG)‐antibody (Ab)–associated diseases (MOGADs) account for a substantial proportion of pediatric and adult patients who present with acquired demyelinating disorders.
C. Keller +11 more
semanticscholar +1 more source
Complement activation in IgA nephropathy
Seminars in Immunopathology, 2021 IgA nephropathy pathogenesis is incompletely understood, and this limits the development of disease-specific biomarkers and effective therapies. Evidence of complement activity in IgA nephropathy is well established.
N. Medjeral-Thomas +2 more
semanticscholar +1 more source
Quantitative detection of red blood cell antibody-mediated complement activation
Zhongguo shuxue zazhi, 2022 Objective To construct an in-vitro model of erythrocyte antibody-mediated complement activation, and establish quantitative detection methods based on flow cytometry and spectrophotometry, so as to explore the correlation of anti-body titers and ...
Zhongying WANG +9 more
doaj +1 more source
Proceedings of the National Academy of Sciences of the United States of America, 2020 Significance The new SARS-CoV-2 pandemic leads to COVID-19 with respiratory failure, substantial morbidity, and significant mortality. Overactivation of the innate immune response is postulated to trigger this detrimental process.
J. Holter +31 more
semanticscholar +1 more source
Platelets, 2022 Platelet transfusion refractoriness is a serious clinical concern that complicates the management of thrombocytopenic patients. Previous studies have suggested a potential role for both complement and platelet activation based on in vitro analyses of ...
Alexander Åkesson +7 more
doaj +1 more source