Results 11 to 20 of about 610,671 (334)
Complement activation in placental malaria [PDF]
Frontiers in Microbiology, 2015 Sixty percent of all pregnancies worldwide occur in malaria endemic regions. Pregnant women are at greater risk of malaria infection than their non-pregnant counterparts and are more likely to develop severe disease.
Chloe Ross McDonald +2 more
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Overview of Complement Activation and Regulation [PDF]
Seminars in Nephrology, 2013 SummaryComplement is an important component of the innate immune system that is crucial for defense from microbial infections and for clearance of immune complexes and injured cells.
Noris, Marina, Remuzzi, Giuseppe
core +4 more sources
Pentraxins in Complement Activation and Regulation [PDF]
Frontiers in Immunology, 2018 The complement is the first line of immune defense system involved in elimination of invading pathogens and dying host cells. Its activation is mainly triggered by immune complexes or pattern recognition molecules (PRMs) upon recognition against non-self
Ying Jie Ma, Peter Garred
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Complement Activation and Thrombotic Microangiopathies [PDF]
Clinical Journal of the American Society of Nephrology, 2019 Background and objectivesAtypical hemolytic uremic syndrome is a form of thrombotic microangiopathy caused by dysregulation of the alternative complement pathway. There is evidence showing complement activation in other thrombotic microangiopathies. The aim of this study was to evaluate complement activation in different thrombotic microangiopathies ...
Marta Palomo +36 more
openaire +9 more sources
Pathways of complement activation in glomerulonephritis [PDF]
Kidney International, 1972 Pathways of complement activation in glomerulonephritis.Systemic lupus erythematosus and hypocomplementemic glomerulonephritis are characterized by depressed CH50 and C3 levels, but the complement profiles in these two diseases show marked differences.Measurement of hemolytic activity of C1, C4 and C2 and of protein concentrations by radial ...
Nancy H. Holland +2 more
openalex +3 more sources
Why Our Next President May Keep His or her Senate Seat: A Conjecture on the Constitution’s Incompatibility Clause [PDF]
, 2009 Heart diseases are common and significant contributors to worldwide mortality and morbidity. During recent years complement mediated inflammation has been shown to be an important player in a variety of heart diseases.
Aukrust, Pal +7 more
core +3 more sources
Complement activation and protein adsorption by carbon nanotubes [PDF]
, 2006 As a first step to validate the use of carbon nanotubes as novel vaccine or drug delivery devices, their interaction with a part of the human immune system, complement, has been explored.
Flahaut, Emmanuel +5 more
core +2 more sources
Pulmonary complement depositions in autopsy of critically ill patients have no relation with ARDS
Intensive Care Medicine Experimental, 2019 Background The complement system has frequently been suggested to play a role in the pathophysiology of acute respiratory distress syndrome (ARDS).
Friso M. de Beer +6 more
doaj +1 more source
Complement activation in IgA nephropathy [PDF]
Seminars in Immunopathology, 2021 AbstractIgA nephropathy pathogenesis is incompletely understood, and this limits the development of disease-specific biomarkers and effective therapies. Evidence of complement activity in IgA nephropathy is well established. However, a growing body of research indicates complement activity is an important contributor to IgA nephropathy pathology.
Nicholas R. Medjeral-Thomas +2 more
openaire +4 more sources
Paths reunited: initiation of the classical and lectin pathways of complement activation [PDF]
, 2010 Understanding the structural organisation and mode of action of the initiating complex of the classical pathway of complement activation (C1) has been a central goal in complement biology since its isolation almost 50 years ago.
Keeble, Anthony H. +4 more
core +1 more source