Results 131 to 140 of about 3,146 (147)
Some of the next articles are maybe not open access.
The Journal of Immunology, 1979
Abstract Nephritic Factor (NF), the potent alternative pathway activator, which is occasionally found in association with certain types of nephritis has recently been identified as an IgG class autoantibody specific for the C3 convertase of the alternative pathway.
A T, Sobel, N R, Cooper, R D, Schreiber
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Abstract Nephritic Factor (NF), the potent alternative pathway activator, which is occasionally found in association with certain types of nephritis has recently been identified as an IgG class autoantibody specific for the C3 convertase of the alternative pathway.
A T, Sobel, N R, Cooper, R D, Schreiber
openaire +2 more sources
Blood, 2009
Abstract Abstract 157 In PNH, red blood cells (RBCs) lack key complement control proteins, CD55 and CD59 and are therefore sensitive to complement activation and intravascular hemolysis. These regulatory proteins function at two different steps in the complement cascade; CD55 (decay accelerating factor, DAF) controls the ...
Ronald P Taylor +3 more
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Abstract Abstract 157 In PNH, red blood cells (RBCs) lack key complement control proteins, CD55 and CD59 and are therefore sensitive to complement activation and intravascular hemolysis. These regulatory proteins function at two different steps in the complement cascade; CD55 (decay accelerating factor, DAF) controls the ...
Ronald P Taylor +3 more
openaire +1 more source
Cancer Immunology, Immunotherapy, 2019 Anti-CD20 monoclonal antibodies (mAbs) rituximab and ofatumumab are potent activators of the classical complement pathway, and have been approved for the treatment of B-cell malignancies.
Anna Felberg +2 more
exaly +2 more sources
Trypanosoma lewisi: restriction of alternative complement pathway C3/C5 convertase activity.
Experimental parasitology, 1987The rat parasite Trypanosoma lewisi was incubated in vitro with rat or human serum, washed, and extracted in detergent. Extracts were fractionated by electrophoresis in denaturing gels, transferred to nitrocellulose, allowed to renature, then immunoblotted with polyclonal antibodies to rat complement component C3 and human complement components C3, C5,
J E, Sturtevant, A E, Balber
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Clinical and experimental immunology, 1983
Activation of complement may result in the generation of the amplification convertase C3bBb. This convertase can be stabilized by properdin (P) or C3NeF. C3bBbP is susceptible to inactivation by beta 1H, while C3bBbNeF is relatively resistant. Since it has been shown that the human erythrocyte C3b receptor (CR1) is able to inactivate C3bBbP, the ...
M R, Daha, D J, Kok, L A, Van Es
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Activation of complement may result in the generation of the amplification convertase C3bBb. This convertase can be stabilized by properdin (P) or C3NeF. C3bBbP is susceptible to inactivation by beta 1H, while C3bBbNeF is relatively resistant. Since it has been shown that the human erythrocyte C3b receptor (CR1) is able to inactivate C3bBbP, the ...
M R, Daha, D J, Kok, L A, Van Es
openaire +1 more source
MHC Class III products: an electron microscopic study of the C3 convertases of human complement.
Journal of Experimental Medicine, 1984C W Vogel, Muller-Eberhard H J
exaly
Immune evasion by a staphylococcal complement inhibitor that acts on C3 convertases
Nature Immunology, 2005Suzan H M Rooijakkers +2 more
exaly
Complement Component C2: the Classical and Lectin Pathway C3/C5 Convertases
2013openaire +1 more source
Substrate recognition by complement convertases revealed in the C5–cobra venom factor complex
EMBO Journal, 2011Nick S Laursen +2 more
exaly
Structure/function of C5 convertases of complement
International Immunopharmacology, 2001Nenoo Rawal, M K Pangburn
exaly