Results 131 to 140 of about 26,149 (232)
Nanofibrous Platforms for Advanced Wound Therapeutics: Mechanisms, Materials, and Clinical Horizons
The fabrication of nanofiber dressings from diverse natural and synthetic polymers offers a robust platform for chronic wound management. By encapsulating therapeutic drugs and bioactive agents, these dressings can simultaneously attenuate chronic inflammation and microbial infection while actively stimulating angiogenesis, addressing the primary ...
Wanho Cho, Chungmo Yang, Hyuk Sang Yoo
wiley +1 more source
Targeting Tumor Stroma: Current Challenges and Future Directions
Figure 1. Mechanism of ECM reprogramming. Cancer‐associated fibroblasts (CAFs), cancer‐associated macrophages (CAMs), and other mesenchymal cells alter the ECM composition and increase its stiffness by depositing matrix components such as collagen and hyaluronic acid, and secreting cross‐linking agents like lysyl oxidase homolog 2 (LOXL2).
Siwei Wang +7 more
wiley +1 more source
Problems on electrorheological fluid flows
We develop a model of an electrorheological fluid such that the fluid is considered as an anisotropic one with the viscosity depending on the second invariant of the rate of strain tensor, on the module of the vector of electric field strength, and on ...
Hoppe, R. H. W., Litvinov, W. G.
core +1 more source
The Combination of Radiotherapy and Complement C3a Inhibition Potentiates Natural Killer cell Functions Against Pancreatic Cancer. [PDF]
Sodji QH +10 more
europepmc +1 more source
Abstract Melt migration in partially molten rocks is commonly described by porous flow models controlled by the hydro‐mechanical compaction length, which effectively explains melt extraction at mid‐ocean ridges. However, this framework cannot account for the paradoxical accumulation of small melt fractions into rhythmic leucosome–melanosome bands in ...
Qingpei Sun +3 more
wiley +1 more source
Targeting Complement C3a Receptor to Improve Outcome After Ischemic Brain Injury. [PDF]
Pekna M, Stokowska A, Pekny M.
europepmc +1 more source
Role for Complement C5 in Eosinophilic Inflammation of Severe Asthma
Complement activation module, particularly C5, is positively associated with eosinophilic inflammation in severe asthma cohorts. Elevated C5 expression correlates with poor lung function improvement and persistent eosinophilic inflammation. Mouse model studies confirm that C5 exacerbates eosinophilic inflammation, highlighting its potential as a ...
Cong Dong +217 more
wiley +1 more source
Impaired Phagocytosis in Peritonitis Exudate Secondary to Complement Consumption [PDF]
Billing, A. +3 more
core +1 more source
Peptide redesign for inhibition of the complement system: Targeting age-related macular degeneration. [PDF]
PurposeTo redesign a complement-inhibiting peptide with the potential to become a therapeutic for dry and wet age-related macular degeneration (AMD).MethodsWe present a new potent peptide (Peptide 2) of the compstatin family.
Cabrera, Andrea P +6 more
core +1 more source

