Results 171 to 180 of about 405,066 (236)

The Pleiotropic Effect of Complement C5a-C5aR1 Pathway in Diseases: From Immune Regulation to Targeted Therapy. [PDF]

Int J Mol Sci
Xu B, Zhou Z, Xiao Y, Liu Q, Xiao T, Lv Z, Wang H.   +6 more
europepmc   +1 more source

Chronic stress promotes pancreatic ductal adenocarcinoma progression via complement C5a-recruited myeloid-derived suppressor cells. [PDF]

Cancer Immunol Immunother
Yang S, Xiao L, Qi P, Liu Z, Chen Z, Wei R, He R, Yu Q, Yan Z, Xiong S, Wang M, Deng Y, Hu J, Zhou L, Feng Z, Deng H.   +15 more
europepmc   +1 more source

The activation of complement C5a-C5aR1 axis in astrocytes facilitates the neuropathogenesis due to EV-A71 infection by upregulating CXCL1. [PDF]

J Virol
Zhu P, Ji W, Li D, Wang F, Sun T, Yang H, Chen S, Zhang W, Jin Y, Duan G.   +9 more
europepmc   +1 more source

Complement C5a Induces Pro-inflammatory Microvesicle Shedding in Severely Injured Patients. [PDF]

Front Immunol, 2020
Karasu E, Demmelmaier J, Kellermann S, Holzmann K, Köhl J, Schmidt CQ, Kalbitz M, Gebhard F, Huber-Lang MS, Halbgebauer R.   +9 more
europepmc   +1 more source

Cardiac Repair after Myocardial Infarction is Controlled by a Complement C5a Receptor 1-Driven Signaling Cascade. [PDF]

Thromb Haemost
Asare Y, Simsekyilmaz S, Köhncke J, Shagdarsuren G, Staudt M, Noels H, Klos A, Fischer JC, Bernhagen J, Zernecke A, Liehn EA, Shagdarsuren E.   +11 more
europepmc   +1 more source

Finerenone Alleviates Over-Activation of Complement C5a-C5aR1 Axis of Macrophages by Regulating G Protein Subunit Alpha i2 to Improve Diabetic Nephropathy. [PDF]

Cells
Li ZH, Sun ZJ, Tang SCW, Zhao MH, Chen M, Chang DY.   +5 more
europepmc   +1 more source

139 Complement C5a regulates squamous carcinogenesis [PDF]

Journal of Investigative Dermatology, 2017
T.R. Medler, L.M. Coussens
openaire   +1 more source

Complement C5a Receptor Signaling in Macrophages Enhances Trained Immunity Through mTOR Pathway Activation. [PDF]

Immune Netw
Shim EH, Kim SH, Kim DJ, Jang YS.
europepmc   +1 more source

Submolecular probing of the complement C5a receptor-ligand binding reveals a cooperative two-site binding mechanism. [PDF]

Commun Biol, 2020
Dumitru AC, Deepak RNVK, Liu H, Koehler M, Zhang C, Fan H, Alsteens D.   +6 more
europepmc   +1 more source

Preclinical Pharmacokinetics of Complement C5a Receptor Antagonists PMX53 and PMX205 in Mice. [PDF]

ACS Omega, 2020
Kumar V, Lee JD, Clark RJ, Noakes PG, Taylor SM, Woodruff TM.   +5 more
europepmc   +1 more source