Results 151 to 160 of about 20,066 (195)

Mechanisms underlying mechanical sensitization induced by complement C5a: the roles of macrophages, TRPV1, and calcitonin gene-related peptide receptors. [PDF]

Pain, 2019
Warwick CA, Shutov LP, Shepherd AJ, Mohapatra DP, Usachev YM.   +4 more
europepmc   +1 more source

Complement C5a Alters the Membrane Potential of Neutrophils during Hemorrhagic Shock. [PDF]

Mediators Inflamm, 2018
Messerer DAC, Denk S, Föhr KJ, Halbgebauer R, Braun CK, Hönes F, Harant J, Fauler M, Frick M, Nußbaum BL, Radermacher P, Hafner S, Huber-Lang MS.   +12 more
europepmc   +1 more source

Deletion of Biliverdin Reductase A in Myeloid Cells Promotes Chemokine Expression and Chemotaxis in Part via a Complement C5a--C5aR1 Pathway. [PDF]

J Immunol, 2019
Bisht K, Canesin G, Cheytan T, Li M, Nemeth Z, Csizmadia E, Woodruff TM, Stec DE, Bulmer AC, Otterbein LE, Wegiel B.   +10 more
europepmc   +1 more source

Dengue severity and profiles of complement activation and immune mediators: A multicenter cohort study in Indonesia. [PDF]

PLoS One
Saptarini I, Masyeni S, Harahap AR, Giantini A, Nugroho P, Handito A, Hendarwan H, Susilo A, Haryanto S, Fitriani D, Sasmono RT, Nelwan EJ.   +11 more
europepmc   +1 more source

Complement in acute kidney injury: a convergent pathogenic pathway in multifactorial renal damage. [PDF]

Front Immunol
Yi D, Yang R, Guo Y, Zhou H, Luan J.
europepmc   +1 more source

The Complosome: An Emerging Intracellular Complement Network in Cancer Development and Therapy. [PDF]

Int J Mol Sci
Zadroga Ł, Lewandowski F, Bębnowska D, Majchrzak A, Czyż A, Niedźwiedzka-Rystwej P.   +5 more
europepmc   +1 more source

Modulator-induced conformational changes in complement C5, implications for function and drug design. [PDF]

Front Immunol
Zhivnov A, Ottochian C, El-Bouri K, Francis R, Campbell R, Macpherson A, Wells S, van den Elsen JM.   +7 more
europepmc   +1 more source

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Complement component 5a (C5a)

International Journal of Biochemistry and Cell Biology, 2009
The 74 amino acid glycoprotein, complement component 5a (C5a), is a potent pro-inflammatory mediator cleaved enzymatically from its precursor, C5, upon activation of the complement cascade. C5a is quickly metabolised by carboxypeptidases, forming the less potent C5adesArg. Acting via a classical G protein-coupled receptor, CD88, C5a and C5adesArg exert
Helga D Manthey, Trent M Woodruff, Stephen M Taylor   +2 more
exaly   +6 more sources