Results 151 to 160 of about 405,066 (236)

Complement 5a (C5a) [PDF]

Science-Business eXchange, 2010
openaire   +1 more source

Persistence of High Levels of Serum Complement C5a in Severe COVID-19 Cases After Hospital Discharge. [PDF]

Front Immunol, 2021
Senent Y, Inogés S, López-Díaz de Cerio A, Blanco A, Campo A, Carmona-Torre F, Sunsundegui P, González-Martín A, Ajona D, Okrój M, Prósper F, Pio R, Yuste JR, Tavira B.   +13 more
europepmc   +1 more source

Young Adult Microglial Deletion of C1q Reduces Engulfment of Synapses and Partially Mitigates Cognitive Impairment in an Aggressive Alzheimer's Disease Mouse Model

Glia, Volume 74, Issue 9, September 2026.
Young adult deletion of microglial C1q reduced engulfment of Vglut1+ synapses and mitigated spatial cognitive deficits at 10 months of age in the amyloidopathy Arctic mouse model of AD. Neither fibrillar amyloid plaques nor soluble or insoluble Aβ levels in the hippocampus were affected by young adult microglial loss of C1q despite reduced phagocytosis
Tiffany J. Petrisko, Shu‐Hui Chu, Angela Gomez‐Arboledas, Blossom Zhang, Andrea J. Tenner   +4 more
wiley   +1 more source

Cytokine‐Driven Hyperinflammation in Long COVID: Mechanisms, Biomarkers, Complement Dysregulation, and Emerging Immunotherapies—A Narrative Review

Health Science Reports, Volume 9, Issue 9, September 2026.
ABSTRACT Background and Aims Long COVID, also known as post‐acute sequelae of SARS‐CoV‐2 infection (PASC), is a multisystem condition characterized by persistent symptoms that continue beyond the acute phase of infection. Growing evidence indicates that sustained immune dysregulation involving cytokine‐mediated inflammation, complement activation ...
Emmanuel Ifeanyi Obeagu
wiley   +1 more source

Complement 3 (C3); C5a [PDF]

Science-Business eXchange, 2013
openaire   +1 more source

Targeting Complement C5a Receptor 1 for the Treatment of Immunosuppression in Sepsis. [PDF]

Mol Ther, 2021
Sommerfeld O, Medyukhina A, Neugebauer S, Ghait M, Ulferts S, Lupp A, König R, Wetzker R, Schulz S, Figge MT, Bauer M, Press AT.   +11 more
europepmc   +1 more source

Targeting m6A Modifications Regulating Ferroptosis Offers Novel Therapy in Diseases

Cell Proliferation, Volume 59, Issue 9, September 2026.
m6A RNA modification regulates ferroptosis by balancing iron metabolism, lipid peroxidation, and antioxidant defenses. Dysregulated m6A signaling disrupts pro‐ and anti‐ferroptotic factors, leading to excess ROS, Fe3+ accumulation, and lipid peroxidation–driven cell death. Targeting m6A‐mediated ferroptotic regulation represents a promising therapeutic
Lida Du, Joshua S. Fleishman, Shuang Wu, Yuan Zhou, Clara X. Wang, Haitong Wang, Yumin Wang, Hongquan Wang   +7 more
wiley   +1 more source

The Complement System in ANCA‐Associated Vasculitis: Mechanistic Insights, Therapeutic Horizons, and Unmet Clinical Needs

Immunity, Inflammation and Disease
Background ANCA‐associated vasculitides (AAV) are autoimmune small‐vessel vasculitides characterized by necrotizing inflammation with few immune deposits (“pauci‐immune” lesions).
Kehinde Sunmboye, Pauline Millan
doaj   +1 more source

Mullins' syndrome: a new gammopathy-related autoinflammatory syndrome resistant to anakinra [PDF]

, 2012
Cavenagh, JD, P.F.K. Yong, H.J. Longhurst, Grigoriadou, S, J.D. Cavenagh, S. Grigoriadou, Manson, AL, A.L. Manson, Buckland, MS, Yong, PFK, M.S. Buckland, Longhurst, HJ   +11 more
core   +1 more source

A Greater Increase in Complement C5a Receptor 1 Level at Onset and a Smaller Decrease in Immunoglobulin G Level after Recovery in Severer Coronavirus Disease 2019 Patients: A New Analysis of Existing Data with a New Two-Tailed t-Test. [PDF]

Biology (Basel), 2023
Ishida T, Takagi K, Wang G, Tanahashi N, Kawanokuchi J, Takagi H, Guo Y, Ma N.   +7 more
europepmc   +1 more source