Results 151 to 160 of about 405,861 (246)
Complement Involvement in Renal Transplantation [PDF]
The complement system is involved in several renal diseases and in renal transplantation (RTx). The authors review the complement cascade and its involvement in innate and adaptive immunity in the field of RTx.
Maurizio Salvadori +2 more
core
K+ Channels in Membrane Potential Dynamics and Migration of Neutrophil Granulocytes
Neutrophil membrane potential dynamics regulate directed migration. Kir2.1 regulates neutrophil membrane potential and indirectly LTB4 secretion. Together with KCa3.1 and KV1.3, it is required for efficient chemotaxis. KCa3.1 and KV1.3 influence neutrophil migration without altering membrane potential, potentially through reduced LTB4 release (KCa3.1 ...
Tahir Ulu +7 more
wiley +1 more source
Complement C5a and adrenal cell function: examining a potential mechanism of adrenal dysfunction in sepsis [PDF]
The complement system is critically involved in the pathogenesis of sepsis. In particular, complement anaphylatoxin C5a is generated in excess during sepsis, leading to cellular dysfunction.
Mrozewski, Lucas
core +1 more source
Complement C5a and Clinical Markers as Predictors of COVID-19 Disease Severity and Mortality in a Multi-Ethnic Population. [PDF]
Cyprian FS +17 more
europepmc +1 more source
ABSTRACT This case report illustrates the real‐world efficacy of complement component 5 inhibitors in a patient with neuromyelitis optica spectrum disorder who switched from rituximab because of B‐cell repopulation occurring early in the course of treatment.
Aram Zabeti
wiley +1 more source
Sickle cell disease inflammation emerges from interconnected cytokine networks. Immune‐informatics integrates multi‐omics, network biology and artificial intelligence to decode inflammatory signatures, predict complications and identify precision therapeutic targets. Abstract Background Sickle cell disease (SCD) is characterised by chronic inflammation
Emmanuel Ifeanyi Obeagu +1 more
wiley +1 more source
Persistence of High Levels of Serum Complement C5a in Severe COVID-19 Cases After Hospital Discharge. [PDF]
Senent Y +13 more
europepmc +1 more source
Microglia‐derived migrasomes induce vascular endothelial pyroptosis through C1qc delivery, uncovering a novel mechanism of blood–brain barrier (BBB) disruption after intracerebral haemorrhage (ICH) and proposing a novel therapeutic strategy targeting extracellular vesicles (EVs).
Mengyuan Li +17 more
wiley +1 more source

