Results 151 to 160 of about 405,861 (246)

Complement Involvement in Renal Transplantation [PDF]

open access: yes, 2015
The complement system is involved in several renal diseases and in renal transplantation (RTx). The authors review the complement cascade and its involvement in innate and adaptive immunity in the field of RTx.
Maurizio Salvadori   +2 more
core  

K+ Channels in Membrane Potential Dynamics and Migration of Neutrophil Granulocytes

open access: yesArchiv der Pharmazie, Volume 359, Issue 10, October 2026.
Neutrophil membrane potential dynamics regulate directed migration. Kir2.1 regulates neutrophil membrane potential and indirectly LTB4 secretion. Together with KCa3.1 and KV1.3, it is required for efficient chemotaxis. KCa3.1 and KV1.3 influence neutrophil migration without altering membrane potential, potentially through reduced LTB4 release (KCa3.1 ...
Tahir Ulu   +7 more
wiley   +1 more source

Complement C5a and adrenal cell function: examining a potential mechanism of adrenal dysfunction in sepsis [PDF]

open access: yes
The complement system is critically involved in the pathogenesis of sepsis. In particular, complement anaphylatoxin C5a is generated in excess during sepsis, leading to cellular dysfunction.
Mrozewski, Lucas
core   +1 more source

Complement C5a and Clinical Markers as Predictors of COVID-19 Disease Severity and Mortality in a Multi-Ethnic Population. [PDF]

open access: yesFront Immunol, 2021
Cyprian FS   +17 more
europepmc   +1 more source

Case Report: Aquaporin‐4–Positive Neuromyelitis Optica Spectrum Disorder: Diagnostic Challenges and Transition From B‐Cell Depletion Therapy to Ravulizumab

open access: yesClinical Case Reports, Volume 14, Issue 10, October 2026.
ABSTRACT This case report illustrates the real‐world efficacy of complement component 5 inhibitors in a patient with neuromyelitis optica spectrum disorder who switched from rituximab because of B‐cell repopulation occurring early in the course of treatment.
Aram Zabeti
wiley   +1 more source

Complement 5a (C5a) [PDF]

open access: yesScience-Business eXchange, 2010
openaire   +1 more source

Cracking the cytokine code in sickle cell disease: Immune‐informatics for precision inflammation mapping, risk prediction and therapeutic discovery

open access: yesClinical and Translational Discovery, Volume 6, Issue 5, October 2026.
Sickle cell disease inflammation emerges from interconnected cytokine networks. Immune‐informatics integrates multi‐omics, network biology and artificial intelligence to decode inflammatory signatures, predict complications and identify precision therapeutic targets. Abstract Background Sickle cell disease (SCD) is characterised by chronic inflammation
Emmanuel Ifeanyi Obeagu   +1 more
wiley   +1 more source

Persistence of High Levels of Serum Complement C5a in Severe COVID-19 Cases After Hospital Discharge. [PDF]

open access: yesFront Immunol, 2021
Senent Y   +13 more
europepmc   +1 more source

C1qc Mediates Blood–Brain Barrier Disruption in a Mouse Model of Intracerebral Haemorrhage Through Microglia‐Derived Migrasomes

open access: yesJournal of Extracellular Vesicles, Volume 15, Issue 10, October 2026.
Microglia‐derived migrasomes induce vascular endothelial pyroptosis through C1qc delivery, uncovering a novel mechanism of blood–brain barrier (BBB) disruption after intracerebral haemorrhage (ICH) and proposing a novel therapeutic strategy targeting extracellular vesicles (EVs).
Mengyuan Li   +17 more
wiley   +1 more source

Complement 3 (C3); C5a [PDF]

open access: yesScience-Business eXchange, 2013
openaire   +1 more source

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