Results 141 to 150 of about 20,066 (195)

Finerenone Alleviates Over-Activation of Complement C5a-C5aR1 Axis of Macrophages by Regulating G Protein Subunit Alpha i2 to Improve Diabetic Nephropathy. [PDF]

Cells
Li ZH, Sun ZJ, Tang SCW, Zhao MH, Chen M, Chang DY.   +5 more
europepmc   +1 more source

Complement C5a Receptor Signaling in Macrophages Enhances Trained Immunity Through mTOR Pathway Activation. [PDF]

Immune Netw
Shim EH, Kim SH, Kim DJ, Jang YS.
europepmc   +1 more source

Submolecular probing of the complement C5a receptor-ligand binding reveals a cooperative two-site binding mechanism. [PDF]

Commun Biol, 2020
Dumitru AC, Deepak RNVK, Liu H, Koehler M, Zhang C, Fan H, Alsteens D.   +6 more
europepmc   +1 more source

Preclinical Pharmacokinetics of Complement C5a Receptor Antagonists PMX53 and PMX205 in Mice. [PDF]

ACS Omega, 2020
Kumar V, Lee JD, Clark RJ, Noakes PG, Taylor SM, Woodruff TM.   +5 more
europepmc   +1 more source

Knockout mouse models reveal the contributions of G protein subunits to complement C5a receptor-mediated chemotaxis. [PDF]

J Biol Chem, 2020
van den Bos E, Ambrosy B, Horsthemke M, Walbaum S, Bachg AC, Wettschureck N, Innamorati G, Wilkie TM, Hanley PJ.   +8 more
europepmc   +1 more source

Enhancement of Macrophage Phagocytosis by Complement Component C5a

Enhancement of Macrophage Phagocytosis by Complement Component C5a
To investigate the modulatory function of complement component C5a in macrophages, the effects of C5a on macrophage phagocytosis were examined by means of fluorescent polystyrene particles and flow cytometry. We found that C5a enhanced the phagocytosis of latex beads in mouse peritoneal macrophages.
openaire  

NETosis Is Induced by Complement Component 5a: Implications in the Pathogenesis of Pyoderma Gangrenosum. [PDF]

J Invest Dermatol
Wang Z, Hornick N, Vague M, Yang D, Keller J, Kody S, Leachman S, Ortega-Loayza AG, Liu Y.   +8 more
europepmc   +1 more source

Complement C5a and Clinical Markers to predict COVID-19 Disease Severity and Mortality in a Multi-ethnic Population

, 2021
Cyprian FS, Suleman M, Abdelhafez I, Doudin A, Danjuma IMM, Mir FA, Parray A, Yousaf Z, Siddiqui MYA, Eldin A, Mulhim M, Al-Shokri S, Abukhattab M, Shaheen R, Elkord E, Al-khal AL, Zouki ANA, Girardi G.   +17 more
europepmc   +1 more source

Study of the neuroregenerative potential of complement c5a protein

Les lésions traumatiques du système nerveux central demeurent sans solution thérapeutique efficace pour restaurer les fonctions perdues. En effet, les axones lésés ne sont pas en mesure de repousser spontanément et de se reconnecter à leurs cibles d’origine en raison d’un environnement défavorable.
openaire   +1 more source

Ligand-induced dimerisation of the complement C5aR and C5L2 receptors by C5a but not C5a-des Arg

Immunobiology, 2012
Croker, Daniel E., Halai, Reena, Fairlie, David P., Cooper, Matthew A.   +3 more
openaire   +3 more sources