Background: Activation of the complement system is one component of the inflammatory response. Various components of the complement system participate in killing foreign organisms, recruiting immune cells, enhancing edema, and stimulating cytokine ...
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Knockout mouse models reveal the contributions of G protein subunits to complement C5a receptor-mediated chemotaxis. [PDF]
J Biol Chem, 2020 van den Bos E +8 more
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Impaired Phagocytosis in Peritonitis Exudate Secondary to Complement Consumption [PDF]
, 1988 Billing, A. +3 more
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NETosis Is Induced by Complement Component 5a: Implications in the Pathogenesis of Pyoderma Gangrenosum. [PDF]
J Invest DermatolWang Z +8 more
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Ligand-induced dimerisation of the complement C5aR and C5L2 receptors by C5a but not C5a-des Arg
Immunobiology, 2012 Croker, Daniel E. +3 more
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Mechanisms underlying mechanical sensitization induced by complement C5a: the roles of macrophages, TRPV1, and calcitonin gene-related peptide receptors. [PDF]
Pain, 2019 Warwick CA +4 more
europepmc +1 more source
Complement C5a Alters the Membrane Potential of Neutrophils during Hemorrhagic Shock. [PDF]
Mediators Inflamm, 2018 Messerer DAC +12 more
europepmc +1 more source
Deletion of Biliverdin Reductase A in Myeloid Cells Promotes Chemokine Expression and Chemotaxis in Part via a Complement C5a--C5aR1 Pathway. [PDF]
J Immunol, 2019 Bisht K +10 more
europepmc +1 more source
Study of the neuroregenerative potential of complement c5a protein
Les lésions traumatiques du système nerveux central demeurent sans solution thérapeutique efficace pour restaurer les fonctions perdues. En effet, les axones lésés ne sont pas en mesure de repousser spontanément et de se reconnecter à leurs cibles d’origine en raison d’un environnement défavorable.
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