Results 11 to 20 of about 38,195 (255)
Serum complement factor C5a in IgG4-related disease [PDF]
Annals of the Rheumatic Diseases, 2018 We read with great interest the correspondence by Umehara et al 1 which discussed the difficulties in the diagnosis of IgG4-related disease (IgG4-RD). They mention that increased IgG4 concentration is not a specific marker for IgG4-RD. Therefore, the markers for the diagnosis and the disease activity of IgG4-RD are demanded. Approximately a quarter of
Shoichi Fukui +4 more
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Deletion of Biliverdin Reductase A in Myeloid Cells Promotes Chemokine Expression and Chemotaxis in Part via a Complement C5a--C5aR1 Pathway. [PDF]
J Immunol, 2019 Bisht K +10 more
europepmc +3 more sources
Complement component 5a (C5A; C5); Complement 5a receptor 1 (C5AR1) [PDF]
Science-Business eXchange, 2008 openalex +3 more sources
Neutralizing Complement C5a Protects Mice with Pneumococcal Pulmonary Sepsis [PDF]
Anesthesiology, 2020 Abstract Background Community-acquired pneumonia and associated sepsis cause high mortality despite antibiotic treatment. Uncontrolled inflammatory host responses contribute to the unfavorable outcome by driving lung and extrapulmonary organ failure.
Holger Müller-Redetzky +18 more
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Modulation of Neutrophil Activity by Soluble Complement Cleavage Products—An In-Depth Analysis
Cells, 2022 The cellular and fluid phase-innate immune responses of many diseases predominantly involve activated neutrophil granulocytes and complement factors.
Lisa Wohlgemuth +14 more
doaj +1 more source
Frontiers in Immunology, 2022 Numerous publications have underlined the link between complement C5a and the clinical course of COVID-19. We previously reported that levels of C5a remain high in the group of severely ill patients up to 90 days after hospital discharge.
Daria Kowalska +21 more
doaj +1 more source
Scientific Reports, 2022 A complement effect on homeostasis during infection is determined by both cytotoxic (activate complement component 5 (C5a) terminal cytotoxic complex (TCC)), and cytoprotective elements (complement factor H (FH), as well as apolipoprotein E (ApoE)). Here,
Krzysztof Laudanski +6 more
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Important roles of C5a and C5aR in tumor development and cancer treatment [PDF]
E3S Web of Conferences, 2019 The complement system is part of the body's innate defense immune system, which can identify and eliminate invasive pathogenic microorganisms to maintain normal life activities.
Yuxuan Wang
doaj +1 more source