Results 171 to 180 of about 11,452 (258)

Thrombospondin-1 inhibits alternative complement pathway activation in antineutrophil cytoplasmic antibody-associated vasculitis. [PDF]

open access: yesJ Clin Invest
Konwar S   +15 more
europepmc   +1 more source

Residual Chemical Shift Anisotropies in the Structure Determination of Small Molecules

open access: yesMagnetic Resonance in Chemistry, Volume 64, Issue 3, Page 286-311, March 2026.
Plasma neutrophil elastase(ELANE) was markedly elevated in patients with alcohol use disorder, indicating a dysregulated protease‐antiprotease inflammatory balance characterised by decreased SERPINA3. ELANE showed excellent diagnostic specificity(AUC = 0.8683), supporting its potential utility as a neuroinflammatory biomarker for AUD.
Nilamoni Nath   +3 more
wiley   +1 more source

Quantum Chemical Properties of Fluorouracil/XZn11O12 (X = Zn, Cu, Fe, Ni) Nanocomplexes and Interactions with Human Serum Albumin

open access: yesChemistryOpen, Volume 15, Issue 3, March 2026.
Adsorption of fluorouracil (5‐FU) on XZn11O12 (X = Zn, Cu, Fe, Ni) nanoclusters and its interactions with human serum albumin (HSA) have been studied using density functional theory and molecular docking. Reduced HOMO‐LUMO gap of 5‐FU@NiZn11O12 nanocomplex suggests enhanced charge transfer activity.
Mohan Bahadur Kshetri   +4 more
wiley   +1 more source

Evidence for Photoinduced Polaron Generation in a High Persistence Length Low Bandgap Conjugated Polymer in Solution. [PDF]

open access: yesJ Phys Chem B
Azzouzi M   +16 more
europepmc   +1 more source

Prokaryotic PfaB is a terminal acyltransferase that determines the final PUFA product

open access: yesProtein Science, Volume 35, Issue 3, March 2026.
Abstract Omega‐3 polyunsaturated fatty acids (PUFAs) are essential for human health due to their numerous beneficial biological properties. These compounds are synthesized in marine bacteria and eukaryotic microalgae by PUFA megasynthases (Pfas), which are evolutionarily related to fatty acid synthases (FAS) and polyketide synthases (PKS). In FAS, PKS,
Nahuel Lofeudo   +5 more
wiley   +1 more source

Turn‐Induction in Peptides Incorporating Novel Cyrene‐Derived α,α‐Disubstituted Amino Acid

open access: yesJournal of Peptide Science, Volume 32, Issue 3, March 2026.
Novel chiral cyrene‐derived Cyr residues were incorporated into peptides. The α,α‐disubstituted amino acid residue was introduced using the Ugi reaction. X‐ray crystallographic analysis of R‐ and S‐Cyr residues indicated preference to adopt left‐ and right‐handed α‐helical conformations, respectively.
Kajumee Bora Bhowal   +2 more
wiley   +1 more source

Complement profiling of sural nerves in chronic-inflammatory demyelinating polyneuropathy. [PDF]

open access: yesActa Neuropathol
Stascheit F   +12 more
europepmc   +1 more source

Visualizing Causal Interactions Across the 2030 Agenda Pillars: Mapping Priorities for Integrated Policy Action

open access: yesSustainable Development, Volume 34, Issue S2, Page 714-756, March 2026.
ABSTRACT We examine the interconnections between the five pillars of the 2030 Agenda, which we constructed using partial synthetic indices of the sustainable development goals (SDGs). We use time series of the 169 targets corresponding to the 17 SDGs from Eurostat, covering the period from 2000 to 2021 for 28 countries.
Najat Bazah   +1 more
wiley   +1 more source

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