Thrombospondin-1 inhibits alternative complement pathway activation in antineutrophil cytoplasmic antibody-associated vasculitis. [PDF]
Konwar S +15 more
europepmc +1 more source
Residual Chemical Shift Anisotropies in the Structure Determination of Small Molecules
Plasma neutrophil elastase(ELANE) was markedly elevated in patients with alcohol use disorder, indicating a dysregulated protease‐antiprotease inflammatory balance characterised by decreased SERPINA3. ELANE showed excellent diagnostic specificity(AUC = 0.8683), supporting its potential utility as a neuroinflammatory biomarker for AUD.
Nilamoni Nath +3 more
wiley +1 more source
Wnt5a Regulates Embryonic Müllerian Duct Development Through the Non-Canonical Wnt PCP Pathway. [PDF]
Kyei-Barffour I +3 more
europepmc +1 more source
Adsorption of fluorouracil (5‐FU) on XZn11O12 (X = Zn, Cu, Fe, Ni) nanoclusters and its interactions with human serum albumin (HSA) have been studied using density functional theory and molecular docking. Reduced HOMO‐LUMO gap of 5‐FU@NiZn11O12 nanocomplex suggests enhanced charge transfer activity.
Mohan Bahadur Kshetri +4 more
wiley +1 more source
Evidence for Photoinduced Polaron Generation in a High Persistence Length Low Bandgap Conjugated Polymer in Solution. [PDF]
Azzouzi M +16 more
europepmc +1 more source
Prokaryotic PfaB is a terminal acyltransferase that determines the final PUFA product
Abstract Omega‐3 polyunsaturated fatty acids (PUFAs) are essential for human health due to their numerous beneficial biological properties. These compounds are synthesized in marine bacteria and eukaryotic microalgae by PUFA megasynthases (Pfas), which are evolutionarily related to fatty acid synthases (FAS) and polyketide synthases (PKS). In FAS, PKS,
Nahuel Lofeudo +5 more
wiley +1 more source
Spatial regulation of ribosomal protein gene expression revealed by spatial transcriptomic analysis in the water fern <i>Ceratopteris richardii</i>. [PDF]
Han J, Li GS.
europepmc +1 more source
Turn‐Induction in Peptides Incorporating Novel Cyrene‐Derived α,α‐Disubstituted Amino Acid
Novel chiral cyrene‐derived Cyr residues were incorporated into peptides. The α,α‐disubstituted amino acid residue was introduced using the Ugi reaction. X‐ray crystallographic analysis of R‐ and S‐Cyr residues indicated preference to adopt left‐ and right‐handed α‐helical conformations, respectively.
Kajumee Bora Bhowal +2 more
wiley +1 more source
Complement profiling of sural nerves in chronic-inflammatory demyelinating polyneuropathy. [PDF]
Stascheit F +12 more
europepmc +1 more source
ABSTRACT We examine the interconnections between the five pillars of the 2030 Agenda, which we constructed using partial synthetic indices of the sustainable development goals (SDGs). We use time series of the 169 targets corresponding to the 17 SDGs from Eurostat, covering the period from 2000 to 2021 for 28 countries.
Najat Bazah +1 more
wiley +1 more source

