Results 41 to 50 of about 419,621 (293)

Proteomic Analysis of Complement Proteins in Membranous Nephropathy

Kidney International Reports, 2020
Introduction: Membranous nephropathy (MN) is the most common cause of nephrotic syndrome in Caucasian adults. Phospholipase A2 receptor (PLA2R)– and exostosin 1 (EXT1)/exostosin 2 (EXT2)–associated MN represent the most common primary and secondary forms
Aishwarya Ravindran, Benjamin Madden, M. Cristine Charlesworth, Rishi Sharma, Amit Sethi, Hanna Debiec, Daniel Cattran, Fernando C. Fervenza, Richard J. Smith, Pierre Ronco, Sanjeev Sethi   +10 more
doaj   +1 more source

Paths reunited: initiation of the classical and lectin pathways of complement activation [PDF]

, 2010
Understanding the structural organisation and mode of action of the initiating complex of the classical pathway of complement activation (C1) has been a central goal in complement biology since its isolation almost 50 years ago.
Schmid, Ralf, Schwaeble, Wilhelm J., Wilhelm J. Schwaeble, Anthony H. Keeble, Russell Wallis, Mitchell, Daniel A., Keeble, Anthony H., Wallis, Russell, Ralf Schmid, Daniel A. Mitchell   +9 more
core   +1 more source

The Patent Ductus Arteriosus in Extremely Preterm Neonates Is More than a Hemodynamic Challenge: New Molecular Insights

Biomolecules, 2022
Complications to preterm birth are numerous, including the presence of a patent ductus arteriosus (PDA). The biological understanding of the PDA is sparse and treatment remains controversial.
Anna Sellmer, Tine Brink Henriksen, Johan Palmfeldt, Bodil Hammer Bech, Julie Astono, Tue Bjerg Bennike, Vibeke Elisabeth Hjortdal   +6 more
doaj   +1 more source

The Role of Complement in Tumors

, 2020
The complement system is an essential part of the innate immune system that is responsible for regulating inflammation, facilitating immune defense mechanisms, and maintaining tissue homeostasis.

core   +1 more source

Crosstalk Between Activated Platelets and the Complement System [Elektronisk resurs]

, 2010
Several studies have shown that complement and thrombotic events co-exist. Platelets have been suspected to act as the bridge between the two cascade systems.
Hamad, Osama A.,, Truedsson, Lennart,, Ekdahl-Nilsson, Kristina,, Nilsson, Bo,   +3 more
core   +8 more sources

The terminal complement pathway component: C8

, 2000
TEDESCO, FRANCESCO, PLUMB M. E., SODETZ J. M.   +2 more
openaire   +2 more sources

Biosynthetic homeostasis and resilience of the complement system in health and infectious diseaseResearch in context

EBioMedicine, 2019
Background: The complement system is a central component of the innate immune system. Constitutive biosynthesis of complement proteins is essential for homeostasis.
Esther Willems, Wynand Alkema, Jenneke Keizer-Garritsen, Anouk Suppers, Michiel van der Flier, Ria H.L.A. Philipsen, Lambert P. van den Heuvel, Elena Volokhina, Renate G. van der Molen, Jethro A. Herberg, Michael Levin, Victoria J. Wright, Inge M.L. Ahout, Gerben Ferwerda, Marieke Emonts, Navin P. Boeddha, Irene Rivero-Calle, Federico Martinon Torres, Hans J.C.T. Wessels, Ronald de Groot, Alain J. van Gool, Jolein Gloerich, Marien I. de Jonge   +22 more
doaj   +1 more source

Proteomic Analysis of Humoral Immune Components in Bronchoalveolar Lavage of Patients Infected or Colonized by Aspergillus fumigatus

Frontiers in Immunology, 2021
Humoral immune components have been individually studied in the context of interaction of host with Aspergillus fumigatus, a major airborne fungal pathogen. However, a global view of the multitude and complex nature of humoral immune components is needed
Sarah Dellière, Sarah Dellière, Sarah Dellière, Magalie Duchateau, Sarah Sze Wah Wong, Quentin Giai Gianetto, Quentin Giai Gianetto, Hélène Guegan, Mariette Matondo, Jean-Pierre Gangneux, Vishukumar Aimanianda   +10 more
doaj   +1 more source

THE EIGHTH COMPONENT OF HUMAN COMPLEMENT (C8): ISOLATION, CHARACTERIZATION, AND HEMOLYTIC EFFICIENCY [PDF]

The Journal of Experimental Medicine, 1969
A method was described allowing the isolation of the eighth component of complement, C8, from human serum. C8 is an immunochemically definable, heretofore unrecognized serum protein with a molecular weight of approximately 150,000 and an electrophoretic mobility of a γ1-globulin.
J A, Manni, H J, Müller-Eberhard
openaire   +2 more sources

Implantable Ionic Memristors Based on Natural Polymer Heterojunctions

Advanced Functional Materials, EarlyView.
We report an implantable natural polymer‐based ionic memristor composed of hyaluronic acid, chitosan, and PDMS. The device achieved 98.94% accuracy in MNIST classification while reducing training time by 36.8% compared with a conventional artificial neural network (ANN).
Dong‐yup Lee, Byung Ik Park, Gihyeon Yim, Hyunjae Yoo, Sangjun Ma, Jundong Park, Jeong‐Yun Sun   +6 more
wiley   +1 more source