Results 31 to 40 of about 419,621 (293)

Complement activation and protein adsorption by carbon nanotubes [PDF]

, 2006
As a first step to validate the use of carbon nanotubes as novel vaccine or drug delivery devices, their interaction with a part of the human immune system, complement, has been explored.
Flahaut, Emmanuel, Sim, Robert B., Sloan, Jeremy, Green, Malcolm L.H., Sim, Edith, Salvador-Morales, Carolina, Green, Malcolm L. H.   +6 more
core   +1 more source

Deficiency of the Seventh Component of Complement in a Taiwanese Boy

Journal of the Formosan Medical Association, 2006
Inherited complement deficiencies are rare, particularly those associated with late components of the complement cascade. We report a 5-year-4-month-old Taiwanese boy with systemic meningococcal infection who had undetectable CH50 level of < 6 U/mL ...
Yi-Chi Chiang, Shyh-Dar Shyur, Li-Hsin Huang, Ta-Chzng Wen, Mao-Tsair Lin, Hwai-Chih Yang, Pei-Hsuan Liang   +6 more
doaj   +1 more source

Engineering novel complement activity into a pulmonary surfactant protein [PDF]

, 2010
Complement neutralizes invading pathogens, stimulates inflammatory and adaptive immune responses, and targets non- or altered-self structures for clearance.
Toth, Julia, Wilhelm J. Schwaeble, Christopher Furze, Russell Wallis, Keeble, A. H., Julia Toth, Keeble, Anthony H., Girija, Umakhanth Venkatraman, Wallis, Russell, Mitchell, D. A., Daniel A. Mitchell, Toth, J., Schwaeble, W. J., Schwaeble, Wilhelm J., Anthony H. Keeble, Furze, C., Umakhanth Venkatraman Girija, Furze, Christopher M., Mitchell, Daniel A., Wallis, R., Venkatraman Girija, U.   +20 more
core   +1 more source

Genetic Association of the Porcine C9 Complement Component with Hemolytic Complement Activity [PDF]

Asian-Australasian Journal of Animal Sciences, 2015
The complement system is a part of the natural immune regulation mechanism against invading pathogens. Complement activation from three different pathways (classical, lectin, and alternative) leads to the formation of C5-convertase, an enzyme for ...
D. V. A. Khoa, K. Wimmers
doaj   +1 more source

Functional Complement Analysis Can Predict Genetic Testing Results and Long-Term Outcome in Patients With Complement Deficiencies

Frontiers in Immunology, 2018
BackgroundPrevalence of complement deficiencies (CDs) is markedly higher in Slovenian primary immunodeficiency (PID) registry in comparison to other national and international PID registries.ObjectiveThe purposes of our study were to confirm CD and ...
Štefan Blazina, Maruša Debeljak, Mitja Košnik, Mitja Košnik, Saša Simčič, Sanja Stopinšek, Gašper Markelj, Nataša Toplak, Nataša Toplak, Peter Kopač, Breda Zakotnik, Marko Pokorn, Tadej Avčin, Tadej Avčin   +13 more
doaj   +1 more source

Two types of dysfunctional eighth component of complement (C8) molecules in C8 deficiency in man. Reconstitution of normal C8 from the mixture of two abnormal C8 molecules. [PDF]

Journal of Clinical Investigation, 1983
Restoration of hemolytic activity was examined in sera from seven unrelated eighth component of complement (C8)-deficient subjects. The sera fell into two groups, depending on whether hemolytic activity was restored by the addition of the beta-chain (group 1) or the alpha-gamma-subunit (group 2) purified from normal human C8.
F, Tedesco, P, Densen, M A, Villa, B H, Petersen, G, Sirchia   +4 more
openaire   +2 more sources

Comparative Analysis of Serum Proteins Between Hepatitis B Virus Genotypes B and C Infection by DIA-Based Quantitative Proteomics

Infection and Drug Resistance, 2021
Yunqing Chen,1,2 Dahai Wei,1– 3 Min Deng1– 3 1Department of Infectious Diseases, Affiliated Hospital of Jiaxing University, Jiaxing, People’s Republic of China; 2Department of Infectious Diseases, First Hospital of Jiaxing, Jiaxing, People’s Republic of ...
Chen Y, Wei D, Deng M
doaj  

Novel mechanisms of immune evasion by Schistosoma mansoni

Memorias do Instituto Oswaldo Cruz, 1995
The interaction of Schistosoma mansoni with its host's immune system is largely affected by multiple specific and non-specific evasion mechanisms employed by the parasite to reduce the host's immune reactivity. Only little is known about these mechanisms
Zvi Fishelson
doaj   +1 more source

Complement factor H-related proteins CFHR2 and CFHR5 represent novel ligands for the infection-associated CRASP proteins of Borrelia burgdorferi [PDF]

, 2010
Background: One virulence property of Borrelia burgdorferi is its resistance to innate immunity, in particular to complement-mediated killing. Serum-resistant B.
Teresia Hallström, Hallström Teresia, Christine Skerka, Beckhaus Tobias, Skerka, Christine, Karas Michael, Hannes Eberhardt, Michael Karas, Barbara Uzonyi, Corinna Siegel, Kraiczy Peter, Eberhardt, Hannes, Uzonyi Barbara, Zipfel, Peter F., Beckhaus, Tobias, Peter Kraiczy, Karas, Michael (Prof. Dr.), Stevenson, Brian, Peter F Zipfel, Stevenson Brian, Uzonyi, Barbara, Brian Stevenson, Peter F. Zipfel, Siegel, Corinna, Hallström, Teresia, Kraiczy, Peter, Tobias Beckhaus, Eberhardt Hannes, Skerka Christine, Wallich, Reinhard, Zipfel Peter F., Reinhard Wallich, Siegel Corinna, Karas, Michael, Wallich Reinhard   +34 more
core   +2 more sources

Terminal complement complexes with or without C9 potentiate antimicrobial activity against Neisseria gonorrhoeae

mBio
The complement cascade is a front-line defense against pathogens. Complement activation generates the membrane attack complex (MAC), a 10–11 nm diameter pore formed by complement proteins C5b through C8 and polymerized C9. The MAC embeds within the outer
Evan R. Lamb, Alison K. Criss
doaj   +1 more source