Outer membrane protein OMP76 of Riemerella anatipestifer contributes to complement evasion and virulence by binding to duck complement factor vitronectin [PDF]
Riemerella anatipestifer is an important bacterial pathogen in poultry. Pathogenic bacteria recruit host complement factors to resist the bactericidal effect of serum complement.
Sen Li +11 more
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Complement evasion factor (CEF), a novel immune evasion factor of Streptococcus pyogenes [PDF]
Streptococcus pyogenes, a leading human pathogen, is responsible for a wide range of diseases, including skin and soft tissue infections and severe invasive diseases. S.
Haniyeh Aghababa +5 more
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Complement Evasion Strategies of Viruses: An Overview [PDF]
Being a major first line of immune defense, the complement system keeps a constant vigil against viruses. Its ability to recognize large panoply of viruses and virus-infected cells, and trigger the effector pathways, results in neutralization of viruses ...
Palak Agrawal +4 more
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The Surface-Exposed Protein SntA Contributes to Complement Evasion in Zoonotic Streptococcus suis [PDF]
Streptococcus suis is an emerging zoonotic pathogen causing streptococcal toxic shock like syndrome (STSLS), meningitis, septicemia, and even sudden death in human and pigs.
Simin Deng +10 more
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Candidiasis: Insights into Virulence Factors, Complement Evasion and Antifungal Drug Resistance [PDF]
Invasive fungal infections constitute a substantial global health burden, with invasive candidiasis representing approximately 70% of reported cases worldwide.
Nidaa Riaz Gaffar +2 more
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Complement Evasion: An Effective Strategy That Parasites Utilize to Survive in the Host [PDF]
Parasitic infections induce host immune responses that eliminate the invading parasites. However, parasites have evolved to develop many strategies to evade host immune attacks and survive in a hostile environment. The complement system acts as the first
Shuai Shao +4 more
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Complement Evasion in Borrelia spirochetes: Mechanisms and Opportunities for Intervention [PDF]
Lyme disease (LD) is an increasingly prevalent, climate change-accelerated, vector-borne infectious disease with significant morbidity and cost in a proportion of patients who experience ongoing symptoms after antibiotic treatment, a condition known as ...
Jonathan W. Locke
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IgM cleavage by Streptococcus suis reduces IgM bound to the bacterial surface and is a novel complement evasion mechanism [PDF]
Streptococcus suis (S. suis) causes meningitis, arthritis and endocarditis in piglets. The aim of this study was to characterize the IgM degrading enzyme of S.
Viktoria Rungelrath +12 more
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Crystal structure of Trichinella spiralis calreticulin and the structural basis of its complement evasion mechanism involving C1q [PDF]
Helminths produce calreticulin (CRT) to immunomodulate the host immune system as a survival strategy. However, the structure of helminth-derived CRT and the structural basis of the immune evasion process remains unclarified. Previous study found that the
Zhihui Jia +11 more
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Factor H Family Proteins in Complement Evasion of Microorganisms [PDF]
Human-pathogenic microbes possess various means to avoid destruction by our immune system. These include interactions with the host complement system that may facilitate pathogen entry into cells and tissues, expression of molecules that defuse the ...
Mihály Józsi
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