Results 11 to 20 of about 80,611 (190)
Hijacking Factor H for Complement Immune Evasion [PDF]
Frontiers in Immunology, 2021 The complement system is an essential player in innate and adaptive immunity. It consists of three pathways (alternative, classical, and lectin) that initiate either spontaneously (alternative) or in response to danger (all pathways). Complement leads to
Sara R. Moore +3 more
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Hijacking Complement Regulatory Proteins for Bacterial Immune Evasion [PDF]
Frontiers in Microbiology, 2016 The human complement system plays an important role in the defense against invading pathogens, inflammation and homeostasis. Invading microbes, such as bacteria, directly activate the complement system resulting in the formation of chemoattractants and ...
Elise Sofie Hovingh +4 more
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Complement Attack against Aspergillus and Corresponding Evasion Mechanisms
Interdisciplinary Perspectives on Infectious Diseases, 2012 Invasive aspergillosis shows a high mortality rate particularly in immunocompromised patients. Perpetually increasing numbers of affected patients highlight the importance of a clearer understanding of interactions between innate immunity and fungi ...
Cornelia Speth, Günter Rambach
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Complement Evasion by Lyme Disease Spirochetes. [PDF]
Trends Microbiol, 2020 The complement system is an ancient arm of the innate immune system that plays important roles in pathogen recognition and elimination. Upon activation by microbes, complement opsonizes bacterial surfaces, recruits professional phagocytes, and causes bacteriolysis.
Skare JT, Garcia BL.
europepmc +4 more sources
Complement Evasion Strategies of Human Pathogenic Bacteria. [PDF]
Indian J Microbiol, 2020 Human pathogens need to overcome an elaborate network of host defense mechanisms in order to establish their infection, colonization, proliferation and eventual dissemination. The interaction of pathogens with different effector molecules of the immune system results in their neutralization and elimination from the host.
Sharma S, Bhatnagar R, Gaur D.
europepmc +4 more sources
Complement Evasion by Pathogenic Leptospira. [PDF]
Front Immunol, 2016 Leptospirosis is a neglected infectious disease caused by spirochetes from the genus Leptospira. Pathogenic microorganisms, notably those which reach the blood circulation such as Leptospira, have evolved multiple strategies to escape the host complement system, which is important for innate and acquired immunity.
Fraga TR, Isaac L, Barbosa AS.
europepmc +4 more sources
Complement Evasion Contributes to Lyme Borreliae-Host Associations. [PDF]
Trends Parasitol, 2020 Lyme disease is the most common vector-borne disease in the northern hemisphere and is caused by spirochetes of the Borrelia burgdorferi sensu lato complex. Lyme borreliae infect diverse vertebrate reservoirs without triggering apparent manifestations in these animals; however, Lyme borreliae strains differ in their reservoir hosts. The mechanisms that
Lin YP +3 more
europepmc +4 more sources
Microbiology Spectrum, 2023 Plasmodium parasites are the etiological agents of malaria, a disease responsible for over half a million deaths annually. Successful completion of the parasite’s life cycle in the vertebrate host and transmission to a mosquito vector is contingent upon ...
Medard Ernest +7 more
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Staphylococcus aureus proteins Sbi and Efb recruit human plasmin to degrade complement C3 and C3b [PDF]
, 2012 Upon host infection, the human pathogenic microbe Staphylococcus aureus (S. aureus) immediately faces innate immune reactions such as the activated complement system. Here, a novel innate immune evasion strategy of S. aureus is described.
Barthel, Diana +7 more
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The Defensive Interactions of Prominent Infectious Protozoan Parasites: The Host’s Complement System
Biomolecules, 2022 The complement system exerts crucial functions both in innate immune responses and adaptive humoral immunity. This pivotal system plays a major role dealing with pathogen invasions including protozoan parasites.
Sajad Rashidi +5 more
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