Results 21 to 30 of about 2,111 (96)
Quantitation of 55 Common Human Plasma Proteins in Healthy Young Adults and Correlation with Body Mass Index and Dietary Patterns [PDF]
, 2010 Plasma biomarkers are a useful tool for monitoring dietary exposures and the development of chronic disease. Measuring multiple biomarkers at once provides a more complete characterization of phenotype than measuring single markers.
Ahmed El-Sohemy +8 more
core +2 more sources
Tumor Cell Complementation Groups Based on Myogenic Potential: Evidence for Inactivation of Loci Required for Basic Helix-Loop-Helix Protein Activity [PDF]
Molecular and Cellular Biology, 1996 Basic helix-loop-helix (bHLH) proteins mediate terminal differentiation in many lineages. By using the bHLH protein MyoD, which can dominantly activate the myogenic differentiation program in numerous cell types, we demonstrated that recessive defects in bHLH protein function are present in human tumor lines. In contrast to prior work with primary cell
Stephen J. Tapscott, A N Gerber
openaire +3 more sources
Human complement factor H [PDF]
, 1986 We isolated cDNA clones coding for the functionally important tryptic N-terminal38- kDa fragment of human complement control protein factor H using polyclonal and monoclonal antibodies to screen a human liver cDNA library cloned in a bacterial expression
Dierich, Manfred P. +4 more
core +1 more source
Characterization of the lymphocyte membrane receptor for factor H (β1H- globulin) with an antibody to anti-factor H idiotype [PDF]
, 1982 Antibody to the binding site (idiotype) of anti-factor H was shown to have specificity for both B lymphocyte membrane H receptors and C3b. Goat F(ab’)(2) anti-human H was purified by absorption and elution from H agarose and used for rabbit immunization ...
Lambris, JD, Ross, GD
core +3 more sources
Journal of Biological Chemistry, 1986 S-protein, the inhibitor in plasma of the membrane attack complex of complement, appears to have a second function in coagulation. S-protein during clotting enters into a trimolecular complex with thrombin and antithrombin III (ATIII). Functionally, S-protein in the presence of low concentrations of heparin, protects thrombin from inactivation by ATIII.
John H. Griffin, E R Podack, B Dahlbäck
openaire +3 more sources
Buoyancy regulation and aggregate formation in Amoebobacter purpureus from Mahoney lake [PDF]
, 1992 The meromictic Mahoney Lake (British Columbia, Canada) contains an extremely dense layer of purple sulfur bacteria (Amoebobacter purpureus). The buoyant density of Amoebobacter cells grown in pure culture at saturating light intensity was significantly ...
Bar-Ness +43 more
core +1 more source
Detection of Sulfoquinovosidase Activity in Cell Lysates Using Activity‐Based Probes
Angewandte Chemie, Volume 136, Issue 26, June 21, 2024.The development of activity‐based probes targeting the active site nucleophile of glycoside hydrolase family 31 sulfoquinovosidases is described. The probes are shown to bind covalently by structural biology, mass spectrometry and Cy5 in‐gel fluorescence, are selective for sulfoquinovosidases in whole bacterial cell lysates, and are used to monitor ...
Zirui Li +8 more
wiley +2 more sources
Chemotactic factor inactivator in sera of sarcoid patients. [PDF]
, 1976 Plant and Soil SciencesDoctor of Philosophy (Ph.D.
Kubik, Joan S.
core +3 more sources
Development of Efficient Covalent Inactivators of a Fungal Aspartate Semialdehyde Dehydrogenase
Drug Development Research, Volume 86, Issue 3, May 2025.ABSTRACT Aspartate semialdehyde dehydrogenase (ASADH) catalyzes the second step in the fungal pathway towards the synthesis of threonine, isoleucine, and methionine, and it has been identified as a viable target for antifungal drug development. Our previous work produced a group of vinyl sulfones that function as irreversible covalent inactivators of ...
Samantha N. Friday +14 more
wiley +1 more source
Advanced Science, Volume 12, Issue 14, April 10, 2025.A novel structure‐function relationship is identified for lung‐targeting ionizable lipids with nonpermanent charges. These lipids feature N‐methyl and secondary amine groups in their heads and three tails derived from epoxyalkanes, demonstrating superior pulmonary selectivity and efficiency.
Xiaoyan He +9 more
wiley +1 more source