Tumor Cell Complementation Groups Based on Myogenic Potential: Evidence for Inactivation of Loci Required for Basic Helix-Loop-Helix Protein Activity [PDF]
Basic helix-loop-helix (bHLH) proteins mediate terminal differentiation in many lineages. By using the bHLH protein MyoD, which can dominantly activate the myogenic differentiation program in numerous cell types, we demonstrated that recessive defects in bHLH protein function are present in human tumor lines. In contrast to prior work with primary cell
A N, Gerber, S J, Tapscott
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A Newly Described Control Mechanism of Complement Activation in Patients with Mixed Cryoglobulinemia (Cryoglobulins and Complement) [PDF]
Levels in serum of components of complement were studied in a group of 10 patients with mixed cryoglobulinemia. The profiles found in most patients showed decreased levels of the early complement components C1, C4, and C2, with normal levels of C3 ...
de Rojas, Marta Patarroyo +2 more
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Detection by Paper Electrophoresis of the Protein Denaturation in Heat-inactivated Serum for the Complement Fixation Reaction [PDF]
IN seeking the mechanism to explain an apparent procomplementary activity to canine complement of canine serum activated at 56° C. for 30 min., it was observed that the same serum was anticomplementary if inactivated at 62° C. instead of 56° C.
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Author Correction: Immune evasion of Borrelia miyamotoi: CbiA, a novel outer surface protein exhibiting complement binding and inactivating properties [PDF]
A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has not been fixed in the paper.
Florian Röttgerding +8 more
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Complement activation and regulation in human glomerulonephritis [PDF]
This study was designed to examine closely the extent and means of activation of the complement system in human GN. In order to do this, renal biopsy material was obtained from 104 patients.
Moseley, Hannah L, Moseley, Hannah L.
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Glomerular deposition of complement-control proteins in acute and chronic glomerulonephritis [PDF]
Glomerular deposition of complement-control proteins in acute and chronic glomerulonephritis. Acute poststreptococcal glomerulonephritis (AGN) differed from membranoproliferative glomerulonephritis (MPGN) and lupus nephritis (SLE) in that two of the ...
McAdams, A. James +4 more
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Cyclic AMP mediated modulation of complement protein production [PDF]
We have investigated the mechanisms by which cAMP analogues and phosphodiesterase inhibitors, reduced the production of C2 by monocytes in culture. Pulse label studies with 3H-labelled aminoacids showed that dibutyryl cAMP (dbcAMP) impaired the secretion
Lappin, D., Whaley, K.
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Effect of lipopolysaccharide on C3 and C5 production by human lung cells [PDF]
Although studies to date have demonstrated the ability of the monocyte/macrophage to produce C components in vitro, very few studies on C production by nonhepatic tissue cells have been reported.
Rothman, Barbara L. +4 more
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Human papillomavirus 16 E7 inactivator of retinoblastoma family proteins complements human cytomegalovirus lacking UL97 protein kinase [PDF]
Several different families of DNA viruses encode proteins that inactivate the cellular retinoblastoma tumor suppressor protein (pRb), which normally functions to bind E2F transcription factors and restrict expression of genes necessary for cellular ...
Kalejta, Robert F. +5 more
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