Results 21 to 30 of about 1,697 (143)

Tumor Cell Complementation Groups Based on Myogenic Potential: Evidence for Inactivation of Loci Required for Basic Helix-Loop-Helix Protein Activity [PDF]

open access: yesMolecular and Cellular Biology, 1996
Basic helix-loop-helix (bHLH) proteins mediate terminal differentiation in many lineages. By using the bHLH protein MyoD, which can dominantly activate the myogenic differentiation program in numerous cell types, we demonstrated that recessive defects in bHLH protein function are present in human tumor lines. In contrast to prior work with primary cell
A N, Gerber, S J, Tapscott
openaire   +2 more sources

A Newly Described Control Mechanism of Complement Activation in Patients with Mixed Cryoglobulinemia (Cryoglobulins and Complement) [PDF]

open access: yes, 1980
Levels in serum of components of complement were studied in a group of 10 patients with mixed cryoglobulinemia. The profiles found in most patients showed decreased levels of the early complement components C1, C4, and C2, with normal levels of C3 ...
de Rojas, Marta Patarroyo   +2 more
core   +1 more source

Detection by Paper Electrophoresis of the Protein Denaturation in Heat-inactivated Serum for the Complement Fixation Reaction [PDF]

open access: yesNature, 1956
IN seeking the mechanism to explain an apparent procomplementary activity to canine complement of canine serum activated at 56° C. for 30 min., it was observed that the same serum was anticomplementary if inactivated at 62° C. instead of 56° C.
openaire   +2 more sources

Author Correction: Immune evasion of Borrelia miyamotoi: CbiA, a novel outer surface protein exhibiting complement binding and inactivating properties [PDF]

open access: yesScientific Reports, 2019
A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has not been fixed in the paper.
Florian Röttgerding   +8 more
openaire   +1 more source

Complement activation and regulation in human glomerulonephritis [PDF]

open access: yes, 1981
This study was designed to examine closely the extent and means of activation of the complement system in human GN. In order to do this, renal biopsy material was obtained from 104 patients.
Moseley, Hannah L, Moseley, Hannah L.
core   +1 more source

Glomerular deposition of complement-control proteins in acute and chronic glomerulonephritis [PDF]

open access: yes, 1979
Glomerular deposition of complement-control proteins in acute and chronic glomerulonephritis. Acute poststreptococcal glomerulonephritis (AGN) differed from membranoproliferative glomerulonephritis (MPGN) and lupus nephritis (SLE) in that two of the ...
McAdams, A. James   +4 more
core   +1 more source

Cyclic AMP mediated modulation of complement protein production [PDF]

open access: yes, 1982
We have investigated the mechanisms by which cAMP analogues and phosphodiesterase inhibitors, reduced the production of C2 by monocytes in culture. Pulse label studies with 3H-labelled aminoacids showed that dibutyryl cAMP (dbcAMP) impaired the secretion
Lappin, D., Whaley, K.
core   +1 more source

Effect of lipopolysaccharide on C3 and C5 production by human lung cells [PDF]

open access: yes, 1989
Although studies to date have demonstrated the ability of the monocyte/macrophage to produce C components in vitro, very few studies on C production by nonhepatic tissue cells have been reported.
Rothman, Barbara L.   +4 more
core   +6 more sources

Human papillomavirus 16 E7 inactivator of retinoblastoma family proteins complements human cytomegalovirus lacking UL97 protein kinase [PDF]

open access: yes, 2019
Several different families of DNA viruses encode proteins that inactivate the cellular retinoblastoma tumor suppressor protein (pRb), which normally functions to bind E2F transcription factors and restrict expression of genes necessary for cellular ...
Kalejta, Robert F.   +5 more
core   +1 more source

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