Results 31 to 40 of about 2,111 (96)

Changes in protease inhibitors after acute myocardial infarction. [PDF]

, 1976
Plasma levels of fibrinogen, alpha1-antitrypsin, alpha2-macroglobulin, antithrombin III, and C1 inactivator were measured serially for 10 days in 11 patients after acute myocardial infarction. Both fibrinogen and alpha1-antitrypsin rose markedly to reach
D Ogston, G P Crawford, J A Rennie
core   +2 more sources

ARHGAP29 promotes keratinocyte proliferation and migration in vitro and is dispensable for in vivo wound healing

Developmental Dynamics, Volume 254, Issue 4, Page 310-329, April 2025.
Abstract Background RhoA GTPases play critical roles in actin cytoskeletal remodeling required for controlling a diverse range of cellular functions including cell proliferation, adhesion, migration and changes in cell shape, all required for cutaneous wound healing.
Lindsey Rhea, Tanner Reeb, Emily Adelizzi, Bailey Garnica, Allison Stein, Alexis Kollash, Elliot Dunnwald, Martine Dunnwald   +7 more
wiley   +1 more source

Identification of a C3bi-specific membrane complement receptor that is expressed on lymphocytes, monocytes, neutrophils, and erythrocytes [PDF]

, 1982
Cells expressing a membrane C receptor (CR(3)) specific for C3b-inactivator- cleaved C3b (C3bi) were identified by rosette assay with C3bi-coated sheep erythrocytes (EC3bi) or C3bi-coated fluorescent microspheres (C3bi-ms).
Lambris, JD, Ross, GD
core   +3 more sources

Identification and characterization of DICER‐LIKE genes and their roles in Marchantia polymorpha development and salt stress response

The Plant Journal, Volume 121, Issue 3, February 2025.
SUMMARY DICER‐LIKE (DCL) proteins play a central role in plant small RNA (sRNA) biogenesis. The genome of the early land plant Marchantia polymorpha encodes four DCL proteins: MpDCL1a, MpDCL1b, MpDCL3, and MpDCL4. While MpDCL1a, MpDCL3 and MpDCL4 show high similarities to their orthologs in Physcomitrium patens and Arabidopsis thaliana, MpDCL1b shares ...
Erika Csicsely, Anja Oberender, Anastasia‐Styliani Georgiadou, Johanna Alz, Sebastian Kiel, Nora Gutsche, Sabine Zachgo, Jennifer Grünert, Andreas Klingl, Oguz Top, Wolfgang Frank   +10 more
wiley   +1 more source

The moulting arthropod: a complete genetic toolkit review

Biological Reviews, Volume 99, Issue 6, Page 2338-2375, December 2024.
ABSTRACT Exoskeletons are a defining character of all arthropods that provide physical support for their segmented bodies and appendages as well as protection from the environment and predation. This ubiquitous yet evolutionarily variable feature has been instrumental in facilitating the adoption of a variety of lifestyles and the exploitation of ...
Giulia Campli, Olga Volovych, Kenneth Kim, Werner P. Veldsman, Harriet B. Drage, Idan Sheizaf, Sinéad Lynch, Ariel D. Chipman, Allison C. Daley, Marc Robinson‐Rechavi, Robert M. Waterhouse   +10 more
wiley   +1 more source

Sex differences on constitutive long non‐coding RNA expression: Modulatory effect of estradiol and testosterone in muscle cells

Andrology, Volume 12, Issue 8, Page 1887-1896, November 2024.
Abstract Introduction Despite the growing awareness of sexual dimorphism between males and females under pathological and physiological conditions, sex bias in biomedical research in animal models and patients is still present nowadays. The main objective of this work was to investigate sex differences in constitutive long non‐coding RNA expression in ...
Tresa López‐Royo, Laura Moreno‐Martínez, Leticia Moreno‐García, Ana Cristina Calvo, Raquel Manzano, Rosario Osta   +5 more
wiley   +1 more source

Fluorescent Reporters, Imaging, and Artificial Intelligence Toolkits to Monitor and Quantify Autophagy, Heterophagy, and Lysosomal Trafficking Fluxes

Traffic, Volume 25, Issue 10, October 2024.
Our review reports on qualitative, quantitative, and chronological monitoring of lysosomal protein trafficking, and of autophagic and heterophagic fluxes to acidic, degradative endolysosomes. We provide an up‐to‐date description of available single‐ and tandem‐fluorescent reporters, mono‐ and multi‐modal microscopy techniques, and artificial ...
Mikhail Rudinskiy, Diego Morone, Maurizio Molinari   +2 more
wiley   +1 more source

Baculovirus GP64-pseudotyped HIV-based lentivirus vectors are stabilized against complement inactivation by codisplay of decay accelerating factor (DAF) or of a GP64–DAF fusion protein

Molecular Therapy, 2005
The eventual development of efficient gene transfer vectors for in vivo gene delivery will require the development of a number of important new technologies such as stabilization of vectors against protective mechanisms that destroy or otherwise inactivate foreign infectious agents like gene transfer vectors.
Ghiabe-Henri Guibinga, Theodore Friedmann   +1 more
openaire   +3 more sources

Protein tyrosine phosphatase 1B (PTP1B) function, structure, and inhibition strategies to develop antidiabetic drugs

FEBS Letters, Volume 598, Issue 15, Page 1811-1838, August 2024.
This Review presents the main advances in the study of PTP1B since it was first isolated, and recent contextual information related to this protein. Furthermore, we provide an overview of the role of PTP1B in diabetes and obesity, and the challenges of developing selective, effective, potent, bioavailable, and cell‐permeable compounds that can inhibit ...
Andrea Coronell‐Tovar, Juan P. Pardo, Adela Rodríguez‐Romero, Alejandro Sosa‐Peinado, Luz Vásquez‐Bochm, Patricia Cano‐Sánchez, Laura Iliana Álvarez‐Añorve, Martin González‐Andrade   +7 more
wiley   +1 more source

Enhancing the revelation of key genes and interaction networks in non‐small cell lung cancer with major depressive disorder: A bioinformatics analysis

Health Science Reports, Volume 7, Issue 6, June 2024.
Abstract Background and Aims Lung cancer is ranked as the second most prevalent form of cancer worldwide. Nonsmall cell lung cancer (NSCLC) represents the predominant histological subtype. Research suggests that one‐third of lung cancer patients also experiencing depression. Antidepressants play an indispensable role in the management of NSCLC. Despite
Huan Gui, Xulong Chen, Yingjie Nie, Xiangyan Zhang   +3 more
wiley   +1 more source