Silica Induced Suppression of the Production of Third and Fifth Components of the Complement System by Human Lung CellsIn Vitro [PDF]
B L Rothman+5 more
openalex +1 more source
ABSTRACT Objective To compare the effectiveness of high‐efficacy treatments (HET) and low‐efficacy treatments (LET) in NMOSD patients with anti‐aquaporin‐4 antibodies (AQP4‐ab). Methods In this multi‐center study, we analyzed 183 AQP4‐ab seropositive NMOSD patients who received immunosuppressive treatments (IST).
Xiang Li+10 more
wiley +1 more source
Behavior of Complement System Effectors in Chronic and Acute Coronary Artery Disease. [PDF]
Chiorescu RM+9 more
europepmc +1 more source
ABSTRACT Objective Spinal muscular atrophy (SMA) significantly impacts motor function. This study aimed to assess the persistent burden and unmet needs among currently treated patients with SMA and their caregivers. Methods Two complementary web‐based surveys were distributed in August 2024 among patients with SMA and their caregivers.
Julie A. Parsons+8 more
wiley +1 more source
Characterization of three monoclonal antibodies to membrane co-factor protein (MCP) of the complement system and quantification of MCP by radioassay [PDF]
S-W Cho+4 more
openalex +1 more source
Genetic susceptibility to cerebral palsy involves complement system-mediated neuronal development and plasticity pathway. [PDF]
Kun H+5 more
europepmc +1 more source
ABSTRACT Objective To estimate the risk of epilepsy associated with stroke in a community‐based cohort, with consideration of stroke type, number, and severity. Methods Data from 15,100 Atherosclerosis Risk in Communities (ARIC) Study participants without stroke at baseline (1987–1989) were analyzed through 12/31/2022.
Jiping Zhou+11 more
wiley +1 more source
Microbial evasion of the complement system: a continuous and evolving story. [PDF]
Heggi MT+4 more
europepmc +1 more source
Repeat Expansions in PLIN4 Cause Autosomal Dominant Vacuolar Myopathy With Sarcolemmal Features
ABSTRACT Objective We aim to describe and characterize two unrelated Spanish families suffering from an autosomal dominant autophagic vacuolar myopathy caused by repeat expansions in PLIN4. Methods We evaluated the clinical phenotype and muscle imaging, and performed a genetic workup that included exome sequencing, muscle RNAseq, and long‐read genome ...
Laura Llansó+17 more
wiley +1 more source
Inflammation-Driven Plaque Erosion in Atherosclerosis: A Focus on Complement System Pathways. [PDF]
Ramoni D+5 more
europepmc +1 more source