Results 21 to 30 of about 1,832,799 (306)
Sublytic Terminal Complement Components Induce Eryptosis in Autoimmune Haemolytic Anaemia Related to IgM Autoantibodies [PDF]
, 2019 BACKGROUND/AIMS: Eryptosis, the suicidal death of red blood cells (RBCs), is characterized by phosphatidylserine (PS) exposure at the cell surface. It can be catalysed by a variety of abnormal conditions and diseases.
Balola, Abdelwahab Hassan Ahmed +3 more
core +1 more source
Complement System: An Immunotherapy Target in Colorectal Cancer
Frontiers in Immunology, 2022 Colorectal cancer (CRC) is the third most common malignant tumor and the second most fatal cancer worldwide. Several parts of the immune system contribute to fighting cancer including the innate complement system.
Iman M. Talaat +7 more
doaj +1 more source
COMPLEMENT-MEDIATED ADIPOCYTE LYSIS BY NEPHRITIC FACTOR SERA [PDF]
, 1993 Recent data indicate a previously unsuspected link between the complement system and adipocyte biology. Murine adipocytes produce key components of the alternative pathway of complement and are able to activate this pathway.
Lachmann, PJ +4 more
core +1 more source
Frontiers in Immunology, 2018 The complement system has moved into the focus of drug development efforts in the last decade, since its inappropriate or uncontrolled activation has been recognized in many diseases.
József Dobó +2 more
doaj +1 more source
An update on the role of complement in hepatocellular carcinoma
Frontiers in Immunology, 2022 As a main producer of complement, the environment in the liver is greatly affected by the complement system. Although the complement system is considered to have the ability of nonself discrimination, remarkable studies have revealed the tight ...
Zhijie Xiao +3 more
doaj +1 more source
Hyperbolic Structures and Root Systems [PDF]
, 2010 We discuss the construction of a one parameter family of complex hyperbolic structures on the complement of a toric mirror arrangement associated with a simply laced root system.
Dijk, G. van +2 more
core +3 more sources
British Journal of Anaesthesia, 1979 The existence of the complement system was first recognized at the end of the 19th century by the ability of serum to enhance the destruction of bacteria and the requirement of a heat-labile serum factor necessary for the lysis of red cells. Since then extensive research by many groups of workers led to a detailed understanding of the structure ...
openaire +3 more sources
New insights into the immune functions of podocytes: the role of complement
Molecular and Cellular Pediatrics, 2023 Podocytes are differentiated epithelial cells which play an essential role to ensure a normal function of the glomerular filtration barrier (GFB). In addition to their adhesive properties in maintaining the integrity of the filtration barrier, they have ...
Valentina Bruno +3 more
doaj +1 more source
The complement system in neurodegenerative diseases. [PDF]
Clin Sci (Lond)Nimmo J +6 more
europepmc +3 more sources
Acidosis activates complement system in vitro
Mediators of Inflammation, 1998 We investigated the in vitro effect of different form s of acidosis (pH 7.0) on the formation of anaphylatoxins C3a and C5a. Metabolic acidosis due to addition of hydrochloric acid (10 μ mol/ml blood) or lactic acid (5.5 μ mol/ml) to heparin blood (N=12)
Michael Emeis +5 more
doaj +1 more source