Results 31 to 40 of about 24,757,633 (403)
Respiratory Research, 2022 Background The efficacy and safety of complement inhibition in COVID-19 patients is unclear. Methods A multicenter randomized controlled, open-label trial.
Elisabeth De Leeuw +27 more
doaj +1 more source
Why Our Next President May Keep His or her Senate Seat: A Conjecture on the Constitution’s Incompatibility Clause [PDF]
, 2009 Heart diseases are common and significant contributors to worldwide mortality and morbidity. During recent years complement mediated inflammation has been shown to be an important player in a variety of heart diseases.
Aukrust, Pal +7 more
core +3 more sources
Cell and Tissue Research, 2010 The complement system consists of a tightly regulated network of proteins that play an important role in host defense and inflammation. Complement activation results in opsonization of pathogens and their removal by phagocytes, as well as cell lysis.
Peter A. Ward, J. Vidya Sarma
openaire +4 more sources
A Fibonacci analogue of the two's complement numeration system [PDF]
RAIRO - Theoretical Informatics and Applications 57 (2023) 12, 2022 Using the classic two's complement notation of signed integers, the fundamental arithmetic operations of addition, subtraction, and multiplication are identical to those for unsigned binary numbers. We introduce a Fibonacci-equivalent of the two's complement notation and we show that addition in this numeration system can be performed by a ...
arxiv +1 more source
Complement activation and protein adsorption by carbon nanotubes [PDF]
, 2006 As a first step to validate the use of carbon nanotubes as novel vaccine or drug delivery devices, their interaction with a part of the human immune system, complement, has been explored.
Flahaut, Emmanuel +5 more
core +2 more sources
Complement System Part I – Molecular Mechanisms of Activation and Regulation
Frontiers in Immunology, 2015 Complement is a complex innate immune surveillance system, playing a key role in defense against pathogens and in host homeostasis. The complement system is initiated by conformational changes in recognition molecular complexes upon sensing danger ...
N. Merle +3 more
semanticscholar +1 more source
The good, the bad, and the opportunities of the complement system in neurodegenerative disease
Journal of Neuroinflammation, 2020 The complement cascade is a critical effector mechanism of the innate immune system that contributes to the rapid clearance of pathogens and dead or dying cells, as well as contributing to the extent and limit of the inflammatory immune response.
Nicole D. Schartz, A. Tenner
semanticscholar +1 more source
The tumour microenvironment links complement system dysregulation and hypoxic signalling. [PDF]
, 2018 The complement system is an innate immune pathway typically thought of as part of the first line of defence against "non-self" species. In the context of cancer, complement has been described to have an active role in facilitating cancer-associated ...
Giaccia, Amato J +4 more
core +1 more source
Quantitative multiplex profiling of the complement system to diagnose complement‐mediated diseases
Clinical & Translational Immunology, 2020 Objectives Complement deficiencies are difficult to diagnose because of the variability of symptoms and the complexity of the diagnostic process. Here, we applied a novel ‘complementomics’ approach to study the impact of various complement deficiencies ...
Esther Willems +23 more
doaj +1 more source
Complement System in Brain Architecture and Neurodevelopmental Disorders
Frontiers in Neuroscience, 2020 Current evidence indicates that certain immune molecules such as components of the complement system are directly involved in neurobiological processes related to brain development, including neurogenesis, neuronal migration, synaptic remodeling, and ...
J. Magdalon +5 more
semanticscholar +1 more source