Results 31 to 40 of about 1,832,799 (306)

Francisella tularensis Confronts the Complement System

open access: yesFrontiers in Cellular and Infection Microbiology, 2017
Francisella tularensis has developed a number of effective evasion strategies to counteract host immune defenses, not the least of which is its ability to interact with the complement system to its own advantage.
Susan R. Brock, Michael J. Parmely
doaj   +1 more source

Combined anti-C1-INH and radiotherapy against glioblastoma

open access: yesBMC Cancer, 2023
Background A more effective immune response against glioblastoma is needed in order to achieve better tumor control. Radiotherapy can induce anti-tumor mediated immune reactions, in addition to its dose response effects.
Emma Liljedahl   +7 more
doaj   +1 more source

Nonresonance conditions for arrangements [PDF]

open access: yes, 2002
We prove a vanishing theorem for the cohomology of the complement of a complex hyperplane arrangement with coefficients in a complex local system. This result is compared with other vanishing theorems, and used to study Milnor fibers of line arrangements,
Cohen, D., Dimca, A., Orlik, P.
core   +4 more sources

Antimicrobial peptides and complement in neonatal hypoxia-ischemia induced brain damage [PDF]

open access: yes, 2015
Hypoxic-ischemic encephalopathy (HIE) is a clinical condition in the neonate, resulting from oxygen deprivation around the time of birth. HIE affects 1-5/1000 live births worldwide and is associated with the development of neurological deficits ...
Hristova, M, Rocha-Ferreira, E
core   +1 more source

Preferential association of hepatitis C virus with CD19+ B cells is mediated by complement system [PDF]

open access: yes, 2016
Extrahepatic disease manifestations are common in chronic hepatitis C virus (HCV) infection. The mechanism of HCV-related lymphoproliferative disorders is not fully understood.
Alter, Harvey J.   +7 more
core   +1 more source

The complement system in glioblastoma multiforme

open access: yesActa Neuropathologica Communications, 2018
The human complement system is represents the main effector arm of innate immunity and its ambivalent function in cancer has been subject of ongoing dispute.
T. A. M. Bouwens van der Vlis   +6 more
doaj   +1 more source

Pitfalls in complement analysis: A systematic literature review of assessing complement activation

open access: yesFrontiers in Immunology, 2022
BackgroundThe complement system is an essential component of our innate defense and plays a vital role in the pathogenesis of many diseases. Assessment of complement activation is critical in monitoring both disease progression and response to therapy ...
Ricardo J. M. G. E. Brandwijk   +8 more
doaj   +1 more source

A C3(H20) recycling pathway is a component of the intracellular complement system [PDF]

open access: yes, 2017
An intracellular complement system (ICS) has recently been described in immune and nonimmune human cells. This system can be activated in a convertase-independent manner from intracellular stores of the complement component C3. The source of these stores
Botto   +11 more
core   +2 more sources

Genetic bases of C7 deficiency: systematic review and report of a novel deletion determining functional hemizygosity

open access: yesFrontiers in Immunology, 2023
Primary complement system (C) deficiencies are rare but notably associated with an increased risk of infections, autoimmunity, or immune disorders.
Andrea Balduit   +13 more
doaj   +1 more source

The tumour microenvironment links complement system dysregulation and hypoxic signalling. [PDF]

open access: yes, 2018
The complement system is an innate immune pathway typically thought of as part of the first line of defence against "non-self" species. In the context of cancer, complement has been described to have an active role in facilitating cancer-associated ...
Giaccia, Amato J   +4 more
core   +1 more source

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