Results 91 to 100 of about 11,278 (212)
Normalization of large-scale behavioural data collected from zebrafish [PDF]
, 2019 Many contemporary neuroscience experiments utilize high-throughput approaches to simultaneously collect behavioural data from many animals. The resulting data are often complex in structure and are subjected to systematic biases, which require new ...
Chi Pui Pang +12 more
core +2 more sources
Ring-like Oligomers of Synaptotagmins and Related C2 Domain Proteins [PDF]
, 2016 We recently reported that the C2AB portion of Synaptotagmin 1 (Syt1) could self-assemble into Ca2+-sensitive ring-like oligomers on membranes, which could potentially regulate neurotransmitter release.
Bello, OD +7 more
core +1 more source
Genomic Landscape of High‐Altitude Adaptation in East African Mountain Honey Bees (Apis mellifera)
Ecology and Evolution, Volume 15, Issue 8, August 2025.Highland and lowland honey bees in East Africa exhibit distinct phenotypes despite low overall genetic differentiation. To investigate this further, we sampled honey bees from a mountain system in Uganda (red circle) and compared them with samples from Kenya.
Marco Mazzoni +8 more
wiley +1 more source
Presynaptic proteins complexin-I and complexin-II differentially influence cognitive function in early and late stages of Alzheimer’s disease [PDF]
Acta Neuropathologica, 2016 Progressive accumulation of Alzheimer's disease-related pathology is associated with cognitive dysfunction. Differences in cognitive reserve may contribute to individual differences in cognitive function in the presence of comparable neuropathology. The protective effects of cognitive reserve could contribute differentially in early versus late stages ...
Alfredo, Ramos-Miguel +8 more
openaire +2 more sources
PLoS ONE, 2012 Acrosomal exocytosis (AE) is an intracellular multipoint fusion reaction of the sperm plasma membrane (PM) with the outer acrosomal membrane (OAM). This unique exocytotic event enables the penetration of the sperm through the zona pellucida of the oocyte.
Pei-Shiue J Tsai +3 more
doaj +1 more source
Communications Biology, 2023 Calcium-evoked release of neurotransmitters from synaptic vesicles (SVs) is catalysed by SNARE proteins. The predominant view is that, at rest, complete assembly of SNARE complexes is inhibited (‘clamped’) by synaptotagmin and complexin molecules ...
Christopher A. Norman +3 more
doaj +1 more source
The Ins and Outs of miRNA-Mediated Gene Silencing during Neuronal Synaptic Plasticity [PDF]
, 2016 Neuronal connections through specialized junctions, known as synapses, create circuits that underlie brain function. Synaptic plasticity, i.e., structural and functional changes to synapses, occurs in response to neuronal activity and is a critical ...
Hanley, Jonathan, Rajgor, Dipen
core +3 more sources
Animal Genetics, Volume 56, Issue 4, August 2025.Abstract Early genetic studies have suggested that body size in rabbits can be considered a quantitative trait. Several rabbit breeds can be distinguished based on body size, including a few dwarf breeds differentiated by other morphological characteristics.
Samuele Bovo +8 more
wiley +1 more source
Synaptic Vesicle Recycling at the Developing Presynapse
Journal of Neurochemistry, Volume 169, Issue 8, August 2025.During presynaptic development, the coupling between calcium influx and synaptic vesicles (SVs) tightens with maturity, transitioning from microdomain to nanodomain. In immature neurons, spontaneous SV exocytosis is the dominant SV fusion mode, whereas SV fusion is mostly evoked by action potential firing in mature presynapses.
Nawon Kim, Michael A. Cousin
wiley +1 more source