Results 101 to 110 of about 11,278 (212)

Magnetic behavior of lamellar mnps3 and cdps3 composites with a paramagnetic manganese(iii) macrocyclic guest [PDF]

, 2013
Indexación: ScieloSix new composites derived from the intercalation of the MPS3 phases (M = MnII, CdIII) with the macrocyclic manganese(III) complex [MnL(H2O)2].NO3(H2O) (LH2 = Schiff base macrocyclic ligand derived from the condensation of 2-hydroxy-5 ...
...[et al.]., Garcia, A. M,, Manzur, J., Paredes-Garcia, V., Valencia, P.   +4 more
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The Anaphase-Promoting Complex (APC) ubiquitin ligase affects chemosensory behavior in \u3cem\u3eC. elegans\u3c/em\u3e [PDF]

, 2016
The regulation of fundamental aspects of neurobiological function has been linked to the ubiquitin signaling system (USS), which regulates the degradation and activity of proteins and is catalyzed by E1, E2, and E3 enzymes. The Anaphase-Promoting Complex
Jennings, Alexandra K., Kowalski, Jennifer R., Wang, Julia   +2 more
core   +3 more sources

Genetic Inactivation of the Serotonin Transporter Dysregulates Expression of Neurotransmission Genes and Genome‐Wide DNA Methylation Levels in the Medial Prefrontal Cortex of Male Rats During Postnatal Development

Developmental Neurobiology, Volume 85, Issue 3, July 2025.
ABSTRACT Reduced expression of the serotonin transporter (5‐hydroxytryptamine transporter, 5‐HTT) in early life has been associated with a delay in postnatal brain development and endophenotypes of a variety of neuropsychiatric and neurodevelopmental disorders in adolescence and adulthood.
Yvet Kroeze, Martin Oti, Roel H. M. Cooijmans, Ellen van Beusekom, Leonie I. Kroeze, Anthonieke Middelman, Hans van Bokhoven, Sharon M. Kolk, Judith R. Homberg, Huiqing Zhou   +9 more
wiley   +1 more source

Complexins: Cytosolic proteins that regulate SNAP receptor function

Cell, 1995
A family of proteins called complexins was discovered that compete with alpha-SNAP, but not synaptotagmin, for SNAP receptor binding. Complexins I and II are highly homologous hydrophilic proteins that are tightly conserved, with 100% identity among mouse, rat, and human complexin II. They are enriched in neurons where they colocalize with syntaxin and
McMahon, Harvey T., Missler, Markus, Li, Cai, Südhof, Thomas C.   +3 more
openaire   +2 more sources

Association study of polymorphisms in synaptic vesicle-associated genes, SYN2 and CPLX2, with schizophrenia

Behavioral and Brain Functions, 2005
Background The occurrence of aberrant functional connectivity in the neuronal circuit is one of the integrative theories of the etiology of schizophrenia.
Chung Joo-Ho, Park Jin Kyoung, Hong Mi Suk, Jin Sheng-Yu, Kim Jong Woo, Song Ji Young, Lee Hee Jae, Shibata Hiroki, Fukumaki Yasuyuki   +8 more
doaj   +1 more source

Identification of functional cis-regulatory elements by sequential enrichment from a randomized synthetic DNA library [PDF]

, 2013
BACKGROUND: The identification of endogenous cis-regulatory DNA elements (CREs) responsive to endogenous and environmental cues is important for studying gene regulation and for biotechnological applications but is labor and time intensive. Alternatively,
Ahmadinejad, N., Colby, T., Roccaro, M., Somssich, I.   +3 more
core   +2 more sources

Evaluation of synaptotagmin‐1 action models by all‐atom molecular dynamics simulations

FEBS Open Bio, Volume 15, Issue 5, Page 699-713, May 2025.
We used molecular dynamics simulations to test models proposing that synaptotagmin‐1 facilitates membrane fusion by perturbing lipid bilayers, inducing membrane curvature and/or bridging membranes. The simulations show that synaptotagmin‐1 C2‐domains placed near the site of fusion hinder the ability of SNARE complexes to bring the membranes together ...
Josep Rizo, Klaudia Jaczynska, Christian Rosenmund   +2 more
wiley   +1 more source

Synergistic actions of v-SNARE transmembrane domains and membrane-curvature modifying lipids in neurotransmitter release

eLife, 2020
Vesicle fusion is mediated by assembly of SNARE proteins between opposing membranes. While previous work suggested an active role of SNARE transmembrane domains (TMDs) in promoting membrane merger (Dhara et al., 2016), the underlying mechanism remained ...
Madhurima Dhara, Maria Mantero Martinez, Mazen Makke, Yvonne Schwarz, Ralf Mohrmann, Dieter Bruns   +5 more
doaj   +1 more source

Molecular and Morphological Circuitry of the Octopus Sucker Ganglion

Journal of Comparative Neurology, Volume 533, Issue 5, May 2025.
Each of the prehensile suckers on the octopus arm contains a sucker ganglion embedded in the sucker musculature. The function of this ganglion has long been disputed. We provide molecular evidence that the sucker ganglion comprises sensory and motor elements and demonstrate circuit pathways for local processing as well as connections to central nervous
Cassady S. Olson, Aashna Moorjani, Clifton W. Ragsdale   +2 more
wiley   +1 more source

Flood of June 9, 1957, at Perry, Florida [PDF]

, 1958
Floods occurred on streams in the vicinity of Perry, Taylor County, Florida, on June 9, 1957, as a result of heavy rains from atropical disturbance. Serious flooding occurred in Perry along Spring and Pimple creeks as outlined by the shaded area in ...
Musgrove, R. H.
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