Results 81 to 90 of about 11,278 (212)

Complexing additives to reduce the immiscible phase formed in the hybrid ZnBr2 flow battery [PDF]

, 2017
The zinc-bromine redox flow battery (RFB) is one of a very few commercially viable RFB energy storage system capable of integration with intermittent renewable energy sources to deliver improved energy management.
Berlouis, L., Bryans, D., McMillan, B.G., Spicer, M., Wark, A.   +4 more
core   +1 more source

Structurally and functionally unique complexins at retinal ribbon synapses [PDF]

The Journal of Cell Biology, 2005
Ribbon synapses in retinal sensory neurons maintain large pools of readily releasable synaptic vesicles. This allows them to release several hundreds of vesicles per second at every presynaptic release site. The molecular components that cause this high transmitter release efficiency of ribbon synapses are unknown.
Reim, K., Wegmeyer, H., Brandstätter, J., Xue, M., Rosenmund, C., Dresbach, T., Hofmann, K., Brose, N.   +7 more
openaire   +5 more sources

Proteome analysis of human substantia nigra in Parkinson's disease [PDF]

, 2004
Protein expression has been compared in human substantia nigra specimens from Parkinson's disease (PD) patients and from controls, and 44 proteins expressed in this midbrain region were identified by peptide mass fingerprinting.
Basso, Bonifati, Borden, Conway, Cookson, Coon, Cooper, Finkel, Galvin, Goedert, Golbe, Gu, Gu, Harhangi, Ischiropoulos, Jacobs, Jenner, Junn, Kanda, Krapfenbauer, Krüger, Lang, Leroy, Lewy, Lopiano, Lotharius, Martin, Marz, Mitsumoto, Mitsumoto, Mitsumoto, Mizuno, Mizuno, Morrison, Narhi, Orth, Pocernich, Polymeropoulos, Przedborski, Schonberger, Schulz, Sinha, Spillantini, Tabrizi, Tanaka, Wood   +45 more
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Proteomic Insight Into Alzheimer's Disease Pathogenesis Pathways

PROTEOMICS, Volume 25, Issue 21-22, Page 214-229, November 2025.
ABSTRACT Alzheimer's disease (AD) is a leading cause of dementia, but the pathogenesis mechanism is still elusive. Advances in proteomics have uncovered key molecular mechanisms underlying AD, revealing a complex network of dysregulated pathways, including amyloid metabolism, tau pathology, apolipoprotein E (APOE), protein degradation ...
Taekyung Ryu, Kyungdo Kim, Nicholas Asiimwe, Chan Hyun Na   +3 more
wiley   +1 more source

Functional Analysis of Subunit e of the F\u3csub\u3e1\u3c/sub\u3eF\u3csub\u3eo\u3c/sub\u3e-ATP Synthase of the Yeast \u3cem\u3eSaccharomyces cerevisiae\u3c/em\u3e: Importance of the N-Terminal Membrane Anchor Region [PDF]

, 2005
Mitochondrial F1Fo-ATP synthase complexes do not exist as physically independent entities but rather form dimeric and possibly oligomeric complexes in the inner mitochondrial membrane.
Brunner, Susanne, Dolan, Brigid M., Dunn, Cory D., Everard-Gigot, Valerie, Jensen, Robert E., Stuart, Rosemary A.   +5 more
core   +1 more source

Do trophic subsidies affect the outcome of introductions of a non-native freshwater fish? [PDF]

, 2013
Understanding how environmental variables and human disturbances influence the outcomes of introductions of non-native freshwater fish is integral to their risk management. This can be complex in freshwater ecosystems that receive subsidies that increase
Allen, R., Britton, J.R., Jackson, M.C., Pegg, Josie   +3 more
core   +1 more source

Presynaptic quantal size enhancement counteracts post‐tetanic release depression

The Journal of Physiology, Volume 603, Issue 20, Page 6051-6071, October 15, 2025.
Abstract figure legend Sustained high‐frequency stimulation decreases the number of synaptic vesicles that fuse per action potential at the Drosophila neuromuscular junction. However, the postsynaptic response remains largely unchanged. An increased postsynaptic response to individual vesicles, likely driven by an increase in vesicle size resulting ...
Anu G. Nair, Nasrin Bollmohr, Levin Schökle, Jennifer Keim, José María Mateos Melero, Martin Müller   +5 more
wiley   +1 more source

A role of complexin–lipid interactions in membrane fusion [PDF]

FEBS Letters, 2009
Complexins (Cpxs) and synaptotagmins regulate calcium‐dependent exocytosis. A central helix in Cpx confers specific binding to the soluble N‐ethylmaleimide‐sensitive factor‐attachment protein receptor (SNARE) fusion machinery. An accessory helix in the amino‐terminal region inhibits membrane fusion by blocking SNAREpin zippering.
Seiler, Florian, Malsam, Jörg, Krause, Jean Michel, Söllner, Thomas H.   +3 more
openaire   +2 more sources

Acute introduction of monomeric or multimeric α‐synuclein induces distinct impacts on synaptic vesicle trafficking at lamprey giant synapses

The Journal of Physiology, Volume 603, Issue 20, Page 6207-6227, October 15, 2025.
Abstract figure legend Monomeric and multimeric α‐synuclein were purified from HEK cells and delivered to lamprey reticulospinal (RS) synapses via axonal microinjection, followed by stimulation (20 Hz, 5 min). Ultrastructural analysis showed that both α‐synuclein species impaired intracellular vesicle trafficking, leading to synaptic vesicle loss and ...
Cristina Román‐Vendrell, Jaqulin N. Wallace, Aurelia Hays Watson, Meral Celikag, Tim Bartels, Jennifer R. Morgan   +5 more
wiley   +1 more source

High-yield Escherichia coli -based cell-free expression of human proteins [PDF]

, 2018
Production of sufficient amounts of human proteins is a frequent bottleneck in structural biology. Here we describe an Escherichia coli-based cell-free system which yields mg-quantities of human proteins in N-terminal fusion constructs with the GB1 ...
Michel, Erich, Wüthrich, Kurt
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