Results 71 to 80 of about 11,278 (212)
, 2004 Number of Pages: 6Integrative BiologyGeological ...
Ernst, Carl H., Stuart, James N.
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Alzheimer's &Dementia, Volume 22, Issue 1, January 2026.Abstract INTRODUCTION Alzheimer's disease (AD) study participants may present with cognitive impairment who do not have brain amyloid deposits (Aβ−). Identifying predictive biomarkers for non‐amyloid‐related CI may provide better screening tests for trials seeking only CI Aβ+ participants and new therapy targets.
Richard C. Mohs +11 more
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Real-time visualization of complexin during single exocytic events [PDF]
Nature Neuroscience, 2010 Understanding the fundamental role of soluble NSF attachment protein receptor (SNARE) complexes in membrane fusion requires knowledge of the spatiotemporal dynamics of their assembly. We visualized complexin (cplx), a cytosolic protein that binds assembled SNARE complexes, during single exocytic events in live cells. We found that cplx appeared briefly
An, Seong J. +2 more
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Stabilization of the SNARE Core by Complexin-1 Facilitates Fusion Pore Expansion
Frontiers in Molecular Biosciences, 2021 In the neuron, neurotransmitter release is an essential function that must be both consistent and tightly regulated. The continuity of neurotransmitter release is dependent in large part on vesicle recycling. However, the protein factors that dictate the
Josh Pierson, Yeon-Kyun Shin
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Disentangling the rationale of deforestation to understand better the partial effectiveness of protected areas. A case study for Madagascar's eastern rainforest corridor (2001-12) [PDF]
, 2015 Madagascar's notoriously high level of biodiversity is currently threaten by deforestation. Protected Areas (hereafter “PAs”) remain until now the central instrument to protect it whilst little is known about their environmental effectiveness in the ...
Aubert, Sigrid +7 more
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Beyond the photocycle-how cryptochromes regulate photoresponses in plants? [PDF]
, 2018 Cryptochromes (CRYs) are blue light receptors that mediate light regulation of plant growth and development. Land plants possess various numbers of cryptochromes, CRY1 and CRY2, which serve overlapping and partially redundant functions in different plant
Gu, Lianfeng +6 more
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FASEB BioAdvances, Volume 8, Issue 1, January 2026.GABA‐producing Lactococcus lactis protects against experimental autoimmune encephalomyelitis (EAE) in a mouse source‐dependent manner. The study focuses on the therapeutic potential of genetically engineered gamma‐aminobutyric acid (GABA)‐overproducing Lactococcus lactis (P8s‐GAD L. lactis) in the EAE model.
Kristina Hill +11 more
wiley +1 more source
Cell Reports, 2023 Summary: Neurotransmitter release requires assembly of the SNARE complex fusion machinery, with multiple SNARE-binding proteins regulating when and where synaptic vesicle fusion occurs.
Elizabeth A. Brija +3 more
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Crystallization behavior of poly(lactide)/poly(β-hydroxybutyrate)/talc composites. [PDF]
, 2013 The authors thank Dr. Patrice Lefrançois (CNAM) for SEM observations. They are also grateful to Pr. Jack R. Plimmer USDA, Agricultural Research Service, USA for his discussions during this work.The morphology and miscibility of commercial poly(lactide ...
DOMENEK, Sandra +3 more
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Functional Roles of Complexin 3 and Complexin 4 at Mouse Photoreceptor Ribbon Synapses [PDF]
The Journal of Neuroscience, 2016 Complexins (Cplxs) are SNARE complex regulators controlling the speed and Ca(2+) sensitivity of SNARE-mediated synaptic vesicle fusion. We have shown previously that photoreceptor ribbon synapses in mouse retina are equipped with Cplx3 and Cplx4 and that lack of both Cplxs perturbs photoreceptor ribbon synaptic function; however, Cplx3/4 function in ...
Norbert Babai +8 more
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