Neural Development, 2010 Background In sensory systems with broad bandwidths, polarized receptor cells utilize highly specialized organelles in their apical and basolateral compartments to transduce and ultimately transmit signals to the rest of the nervous system.
Zanazzi George, Matthews Gary
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Binary polypeptide system for permanent and oriented protein immobilization. [PDF]
, 2010 RIGHTS : This article is licensed under the BioMed Central licence at http://www.biomedcentral.com/about/license which is similar to the 'Creative Commons Attribution Licence'.
Bailes, Julian +6 more
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Focused clamping of a single neuronal SNARE complex by complexin under high mechanical tension
Nature Communications, 2018 The SNARE complex enables the fusion of synaptic vesicles with presynaptic membrane via a zippering process that is modulated by the protein complexin, though the precise mechanism remains unclear.
Min Ju Shon, Haesoo Kim, Tae-Young Yoon
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Multiple factors maintain assembled trans-SNARE complexes in the presence of NSF and αSNAP
eLife, 2019 Neurotransmitter release requires formation of trans-SNARE complexes between the synaptic vesicle and plasma membranes, which likely underlies synaptic vesicle priming to a release-ready state.
Eric A Prinslow +4 more
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Communications Biology, 2023 The use of single-molecule optical tweezers shows that complexin-1 shapes the assembly of the Synaptic-soluble N-ethylmaleimide-sensitive factor Attachment Receptor by multiple domains’ coordination.
Tongrui Hao +5 more
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A Reassessment of the Urban Context of the Republican Baths (VIII 5, 36) [PDF]
, 2018 Das Foro Triangolare wird gewöhnlich als Ort eines athletischmilitärischen Komplexes im späthellenistischen Samnitischen Pompeji identifiziert. Benennung (gymnasium, campus, palaestra der vereiia) und Ausdehnung sind zwar umstritten, aber die ...
Trümper, Monika
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Distinct domains of complexin I differentially regulate neurotransmitter release [PDF]
Nature Structural & Molecular Biology, 2007 Complexins constitute a family of four synaptic high-affinity SNARE complex-binding proteins. They positively regulate a late, post-priming step in Ca2+-triggered synchronous neurotransmitter release, but the underlying molecular mechanisms are unclear.
Xue, M. +7 more
openaire +4 more sources
Stability, folding dynamics, and long-range conformational transition of the synaptic t-SNARE complex [PDF]
, 2016 Synaptic soluble N-ethylmaleimide-sensitive factor attachment protein receptors (SNAREs) couple their stepwise folding to fusion of synaptic vesicles with plasma membranes.
Jiao, J +8 more
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The accessory helix of complexin functions by stabilizing central helix secondary structure
eLife, 2014 The presynaptic protein complexin (CPX) is a critical regulator of synaptic vesicle fusion, but the mechanisms underlying its regulatory effects are not well understood. Its highly conserved central helix (CH) directly binds the ternary SNARE complex and
Daniel T Radoff +5 more
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Improvement in Hemodynamic Responses to Metaboreflex Activation after One Year of Training in Spinal Cord Injured Humans [PDF]
, 2014 Spinal cord injured (SCI) individuals show an altered hemodynamic response to metaboreflex activation due to a reduced capacity to vasoconstrict the venous and arterial vessels below the level of the lesion.
Angius, Luca +10 more
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