Results 101 to 110 of about 11,073 (199)
Presynaptic proteins complexin-I and complexin-II differentially influence cognitive function in early and late stages of Alzheimer’s disease [PDF]
Acta Neuropathologica, 2016 Progressive accumulation of Alzheimer's disease-related pathology is associated with cognitive dysfunction. Differences in cognitive reserve may contribute to individual differences in cognitive function in the presence of comparable neuropathology. The protective effects of cognitive reserve could contribute differentially in early versus late stages ...
Alfredo, Ramos-Miguel +8 more
openaire +2 more sources
PLoS ONE, 2012 Acrosomal exocytosis (AE) is an intracellular multipoint fusion reaction of the sperm plasma membrane (PM) with the outer acrosomal membrane (OAM). This unique exocytotic event enables the penetration of the sperm through the zona pellucida of the oocyte.
Pei-Shiue J Tsai +3 more
doaj +1 more source
2012 Alaska's Construction Spending Forecast [PDF]
, 2012 The total value of construction spending “on the street” in Alaska in 2012 will be $7.7 billion, up 3% from 2011.1,2,3 Wage and salary employment in the construction industry will be stable at the same level as last year— 15,800.
Goldsmith, Oliver Scott, Killorin, Mary
core
Time-coded neurotransmitter release at excitatory and inhibitory synapses. [PDF]
, 2016 Communication between neurons at chemical synapses is regulated by hundreds of different proteins that control the release of neurotransmitter that is packaged in vesicles, transported to an active zone, and released when an input spike occurs ...
Afia B. Ali +8 more
core +2 more sources
Evaluation of synaptotagmin‐1 action models by all‐atom molecular dynamics simulations
FEBS Open Bio, Volume 15, Issue 5, Page 699-713, May 2025.We used molecular dynamics simulations to test models proposing that synaptotagmin‐1 facilitates membrane fusion by perturbing lipid bilayers, inducing membrane curvature and/or bridging membranes. The simulations show that synaptotagmin‐1 C2‐domains placed near the site of fusion hinder the ability of SNARE complexes to bring the membranes together ...
Josep Rizo +2 more
wiley +1 more source
Alzheimer’s Research & Therapy, 2022 Background Approximately a third of frontotemporal dementia (FTD) is genetic with mutations in three genes accounting for most of the inheritance: C9orf72, GRN, and MAPT.
Aitana Sogorb-Esteve +38 more
doaj +1 more source
Do trophic subsidies affect the outcome of introductions of a non-native freshwater fish? [PDF]
, 2013 Understanding how environmental variables and human disturbances influence the outcomes of introductions of non-native freshwater fish is integral to their risk management. This can be complex in freshwater ecosystems that receive subsidies that increase
Allen, R. +3 more
core +1 more source
Molecular and Morphological Circuitry of the Octopus Sucker Ganglion
Journal of Comparative Neurology, Volume 533, Issue 5, May 2025.Each of the prehensile suckers on the octopus arm contains a sucker ganglion embedded in the sucker musculature. The function of this ganglion has long been disputed. We provide molecular evidence that the sucker ganglion comprises sensory and motor elements and demonstrate circuit pathways for local processing as well as connections to central nervous
Cassady S. Olson +2 more
wiley +1 more source
Behavioral and Brain Functions, 2005 Background The occurrence of aberrant functional connectivity in the neuronal circuit is one of the integrative theories of the etiology of schizophrenia.
Chung Joo-Ho +8 more
doaj +1 more source
Journal of Neuroscience Research, Volume 103, Issue 5, May 2025.A family of human proteins, encoded by Tubulin Polymerization Promoting Proteins (TPPP), is highly conserved across species. TPPP displays remarkable functional diversity and is implicated in various neurological disorders. Image created with BioRender.com.
Paloma J. Diaz +3 more
wiley +1 more source