Results 121 to 130 of about 2,943 (163)

Cone Snail Venomics: From Novel Biology to Novel Therapeutics

Future Medicinal Chemistry, 2014
Peptide neurotoxins from cone snails called conotoxins are renowned for their therapeutic potential to treat pain and several neurodegenerative diseases. Inefficient assay-guided discovery methods have been replaced by high-throughput bioassays integrated with advanced MS and next-generation sequencing, ushering in the era of 'venomics'. In this review,
Prashanth, Jutty Rajan, Brust, Andreas, Jin, Ai-Hua, Alewood, Paul F., Dutertre, Sebastien, Lewis, Richard J.   +5 more
openaire   +3 more sources

Piscivorous Behavior of a Temperate Cone Snail,Conus californicus

The Biological Bulletin, 2005
Most of the more than 500 species of predatory marine snails in the genus Conus are tropical or semitropical, and nearly all are thought to be highly selective regarding type of prey. Conus californicus Hinds, 1844, is unusual in that it is endemic to the North American Pacific coast and preys on a large variety of benthic organisms, primarily worms ...
Julia, Stewart, William F, Gilly
openaire   +2 more sources

Pharmacology of predatory and defensive venom peptides in cone snails

Molecular BioSystems, 2017
Cone snails use distinct venoms for defence and prey capture. The pharmacology of these neurotoxic peptides have been extensively studied for pharmacological probes, venom evolution mechanisms and potential therapeutics.
Jutty Rajan Prashanth, Sebastien Dutertre, Richard James Lewis   +2 more
openaire   +3 more sources

Venomic study on cone snails (Conus spp.) from South Africa

Toxicon, 2011
From six Conus species (Conus coronatus, Conus lividus, Conus mozambicus f. lautus, Conus pictus, Conus sazanka, Conus tinianus) collected off the eastern coast of South Africa the venoms were analyzed using MALDI-TOF mass spectrometry. Between 56 and 151 molecular masses most in a range of 1000 to 2500 Da, were identified.
Kauferstein, S., Porth, C., Kendel, Y., Wunder, C., Nicke, A., Kordis, D., Favreau, P., Koua, D., Stoecklin, R., Mebs, D.   +9 more
openaire   +3 more sources

Structural and biosynthetic properties of peptides in cone snail venoms

Peptides, 1995
Venoms of the predatory cone snails Conus textile, Conus striatus, and Conus magus were subjected to comprehensive analysis of peptide content. With the fish-eating cone snails C. magus and C. striatus, the most abundant venom peptides were of > 30-50 residues, whereas the predominant peptides in the venom of the mollusc-eating snail, C.
R, Newcomb, S, Gaur, J R, Bell, L, Cruz
openaire   +2 more sources

Phyla Molluska: The Venom Apparatus of Cone Snails

2015
Predatory marine gastropods of the genus Conus comprise similar to 700 species that have evolved a highly specialized envenomation apparatus. This recently evolved genus has developed potent venoms separately for prey capture and defense. Both strategies utilize a complex but different cocktail of venom peptides that is injected through a hollow ...
Dutertre, Sebastien, Griffin, John, Lewis, Richard J.   +2 more
openaire   +2 more sources

The Threat to Cone Snails

Science, 2003
Eric, Chivian, Callum M, Roberts, Aaron S, Bernstein   +2 more
openaire   +2 more sources

HYBRID ECMO AND CONE SNAIL VENOM POISONING

Journal of the American College of Cardiology, 2022
Renato C. Ong, Maria Stephanie Alessa Florentino, Raul Lapitan   +2 more
openaire   +1 more source

Cone Snails

2020
K. Gopakumar, Balagopal Gopakumar
openaire   +1 more source

Integrative oncology: Addressing the global challenges of cancer prevention and treatment

Ca-A Cancer Journal for Clinicians, 2022
Jun J Mao,, Msce, Lorenzo Cohen, Karen M Mustian   +2 more
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