Results 131 to 140 of about 16,099 (174)
Conkazal-M1 from the MKAVA family of conotoxins: A dual-function protease inhibitor and neuroactive peptide. [PDF]
Hackney CM +12 more
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The biomechanics of fish skin: assessing puncture resistance to the dynamic predatory mechanism of cone snails. [PDF]
Baskota B, Zhang B, Anderson PSL.
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Structural similarities reveal an expansive conotoxin family with a two-finger toxin fold. [PDF]
Khilji MS +11 more
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Novel Pharmacological Targets From Indian Cone Snails
Mini-Reviews in Medicinal Chemistry, 2011The oceans are a source of combinatorial library of unique natural products, 'not found in the terrestrial environment'. Marine invertebrates such as sponges, molluscs, bryozoans, tunicates (Urochordata) and their associated microorganisms are the major representatives of promising bioactive compounds.
M Santhana, Ramasamy, S, Manikandan
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Peptide Neurotoxins from Fish-Hunting Cone Snails
Science, 1985To paralyze their more agile prey, the venomous fish-hunting cone snails ( Conus ) have developed a potent biochemical strategy. They produce several classes of toxic peptides (conotoxins) that attack a series of successive physiological targets in the neuromuscular system of the fish.
B M, Olivera +7 more
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Therapeutic Potential of Cone Snail Venom Peptides (Conopeptides)
Current Topics in Medicinal Chemistry, 2012Cone snails have evolved many 1000s of small, structurally stable venom peptides (conopeptides) for prey capture and defense. Whilst < 0.1% have been pharmacologically characterised, those with known function typically target membrane proteins of therapeutic importance, including ion channels, transporters and GPCRs. Several conopeptides reduce pain in
Vetter, Irina, Lewis, Richard J.
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Cone snails lure prey with faux pheromones
C&EN Global Enterprise, 2021Cone snails use venom when hunting their prey. While much is known about the peptides in cone snail venom , the small molecules it contains have until now not been well characterized—especially in ...
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Neurotoxins of Cone Snail Venoms
2002Cone snails are predatory marine mollusks that rely on their venom components to immobilize and capture fish, worms, or other mollusks. Cones employ a number of prey-hunting strategies, ultimately involving the injection of venom through a hollow, harpoon-like, modified-tooth structure (1).
Robert Newcomb, George Miljanich
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