Results 131 to 140 of about 16,099 (174)

Conkazal-M1 from the MKAVA family of conotoxins: A dual-function protease inhibitor and neuroactive peptide. [PDF]

open access: yesProtein Sci
Hackney CM   +12 more
europepmc   +1 more source

Structural similarities reveal an expansive conotoxin family with a two-finger toxin fold. [PDF]

open access: yesProtein Sci
Khilji MS   +11 more
europepmc   +1 more source
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Novel Pharmacological Targets From Indian Cone Snails

Mini-Reviews in Medicinal Chemistry, 2011
The oceans are a source of combinatorial library of unique natural products, 'not found in the terrestrial environment'. Marine invertebrates such as sponges, molluscs, bryozoans, tunicates (Urochordata) and their associated microorganisms are the major representatives of promising bioactive compounds.
M Santhana, Ramasamy, S, Manikandan
openaire   +2 more sources

Peptide Neurotoxins from Fish-Hunting Cone Snails

Science, 1985
To paralyze their more agile prey, the venomous fish-hunting cone snails ( Conus ) have developed a potent biochemical strategy. They produce several classes of toxic peptides (conotoxins) that attack a series of successive physiological targets in the neuromuscular system of the fish.
B M, Olivera   +7 more
openaire   +2 more sources

Therapeutic Potential of Cone Snail Venom Peptides (Conopeptides)

Current Topics in Medicinal Chemistry, 2012
Cone snails have evolved many 1000s of small, structurally stable venom peptides (conopeptides) for prey capture and defense. Whilst < 0.1% have been pharmacologically characterised, those with known function typically target membrane proteins of therapeutic importance, including ion channels, transporters and GPCRs. Several conopeptides reduce pain in
Vetter, Irina, Lewis, Richard J.
openaire   +3 more sources

Cone snails lure prey with faux pheromones

C&EN Global Enterprise, 2021
Cone snails use venom when hunting their prey. While much is known about the peptides in cone snail venom , the small molecules it contains have until now not been well characterized—especially in ...
openaire   +1 more source

Neurotoxins of Cone Snail Venoms

2002
Cone snails are predatory marine mollusks that rely on their venom components to immobilize and capture fish, worms, or other mollusks. Cones employ a number of prey-hunting strategies, ultimately involving the injection of venom through a hollow, harpoon-like, modified-tooth structure (1).
Robert Newcomb, George Miljanich
openaire   +1 more source

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