Connexin36 Expression in the Mammalian Retina: A Multiple-Species Comparison [PDF]
Frontiers in Cellular Neuroscience, 2017 Much knowledge about interconnection of human retinal neurons is inferred from results on animal models. Likewise, there is a lack of information on human retinal electrical synapses/gap junctions (GJ).
Tamás Kovács-Öller +25 more
doaj +6 more sources
Respiratory disturbances and high risk of sudden death in the neonatal connexin‐36 knockout mouse [PDF]
Physiological Reports, 2021 Neural circuits at the brainstem involved in the central generation of the motor patterns of respiration and cardiorespiratory chemoreflexes organize as cell assemblies connected by chemical and electrical synapses.
Leonel F. Pérez‐Atencio +7 more
doaj +3 more sources
Increased phosphorylation of Cx36 gap junctions in the AII amacrine cells of RD retina [PDF]
Frontiers in Cellular Neuroscience, 2015 Retinal degeneration (RD) encompasses a family of diseases that lead to photoreceptor death and visual impairment. Visual decline due to photoreceptor cell loss is further compromised by emerging spontaneous hyperactivity in inner retinal cells.
Elena eIvanova +2 more
doaj +14 more sources
Differential Distribution of Retinal Ca2+/Calmodulin-Dependent Kinase II (CaMKII) Isoforms Indicates CaMKII-β and -δ as Specific Elements of Electrical Synapses Made of Connexin36 (Cx36) [PDF]
Frontiers in Molecular Neuroscience, 2017 AII amacrine cells are essential interneurons of the primary rod pathway and transmit rod-driven signals to ON cone bipolar cells to enable scotopic vision.
Shubhash Chandra Yadav +2 more
exaly +10 more sources
Increased Connexin36 Phosphorylation in AII Amacrine Cell Coupling of the Mouse Myopic Retina [PDF]
Frontiers in Cellular Neuroscience, 2020 Myopia is a substantial public health problem worldwide. In the myopic retina, distant images are focused in front of the photoreceptors. The cells and mechanisms for retinal signaling that account either for emmetropization (i.e., normal refraction) or ...
Seema Banerjee +9 more
doaj +6 more sources
Frequency cumulative effect of subthreshold energy laser-activated remote phosphors irradiation on visual function in guinea pigs [PDF]
International Journal of Ophthalmology, 2022 AIM: To explore the effects of laser-activated remote phosphors (LARP) on visual function in guinea pigs. METHODS: Electroretinogram (ERG) of guinea pigs were observed after LARP irradiation at different frequencies and irradiation times.
Yu-Fei Zhang +8 more
doaj +2 more sources
Modulation of Gap Junction Coupling Within the Islet of Langerhans During the Development of Type 1 Diabetes [PDF]
Frontiers in Physiology, 2022 In type 1 diabetes (T1D), islet dysfunction occurs prior to diabetes onset. Pro-inflammatory cytokines can disrupt insulin secretion and Ca2+ homeostasis.
Nikki L. Farnsworth +11 more
doaj +2 more sources
Inhibition of Connexin 36 attenuates HMGB1-mediated depressive-like behaviors induced by chronic unpredictable mild stress. [PDF]
Brain Behav, 2022 Inhibition of Cx36 in hippocampal neurons might attenuate HMGB1‐mediated depressive‐like behaviors induced by CUMS through down‐regulation of the proinflammatory cytokines and reduction of the excitability and intracellular ion overload. Abstract Background High mobility group box 1 (HMGB1) released by neurons and microglia was demonstrated to be an ...
Jiang Q +7 more
europepmc +2 more sources
Characterizing the rod pathway in cone-dominant thirteen-lined ground squirrels [PDF]
Frontiers in Ophthalmology, 2023 AII-amacrine cells (AIIs) are widely accepted as a critical element of scotopic pathways mediating night vision in the mammalian retina and have been well-characterized in rod-dominant mice, rabbits, and non-human primates.
Riley Ferguson +3 more
doaj +2 more sources
Connexin30.2: in vitro interaction with connexin36 in HeLa cells and expression in AII amacrine cells and intrinsically photosensitive ganglion cells in the mouse retina [PDF]
Frontiers in Molecular Neuroscience, 2016 Electrical coupling via gap junctions is an abundant phenomenon in the mammalian retina and occurs in all major cell types. Gap junction channels are assembled from different connexin subunits, and the connexin composition of the channel confers specific
Arndt eMeyer +8 more
doaj +4 more sources