Results 11 to 20 of about 2,702,233 (230)
Connexin 26 and Connexin 43 in Canine Mammary Carcinoma. [PDF]
Vet Sci, 2019 Incidence of canine mammary carcinoma is two times higher than the rate of human breast cancer. Mammary tumors are the most common type of cancer in intact female dogs and account for about half of all neoplasms in these dogs. Well-established models of breast cancer have shown that neoplastic cells often have a loss of intercellular communication ...
Luu S, Bell C, Schneider S, Nguyen TA.
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Connexins, hearing and deafness: clinical aspects of mutations in the connexin 26 gene
Brain Research Reviews, 2000 Congenital deafness is a very frequent disorder occurring in approximately I in 1000 live births. Mutations in GJB2 encoding for gap junction protein connexin-26 (Cx26) have been established as the basis of autosomal recessive non-syndromic hearing loss and proposed in some rare cases of autosomal dominant form of deafness.
P P, Lefebvre, T R, Van De Water
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Serum connexin 26 as a potential marker of non-syndromic hearing loss
The Egyptian Journal of OtolaryngologyBackground Hearing loss (HL) represents the most common form of sensory impairment in both children and adults. In children, genetic causes account for over 50%. The genetic causes of HL include multiple syndromes associated with HL.
Hend M. Moness +7 more
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Vestibular dysfunction of patients with mutations of Connexin 26
NeuroReport, 2005 The gap junctional network of the inner ear plays an important role in cochlear ionic homoeostasis. Mutations of connexin 26 can induce different types of hearing loss and even deafness. Therefore, it is hypothesized that gap junctions of the human vestibular organ are functionally impaired by mutations of connexin 26.
Ingo, Todt +3 more
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Revista da Sociedade Brasileira de Fonoaudiologia, 2009 Nos últimos anos houve grande progresso na localização de genes associados à deficiência auditiva hereditária, possibilitando diagnósticos cada vez mais precisos e precoces. Mutações no gene da Conexina 26 (GJB2 - Cx26) causam deficiência auditiva.
Paula Michele da Silva Schmidt +1 more
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Immunolocalization of connexin 26 in the developing mouse cochlea
Brain Research Reviews, 2000 Gap junctions play a pivotal role in embryonic development by forming specialized regions of cell-cell communication. In this study, we demonstrate the temporal-spatial distribution of connexin 26 in the embryonic and early postnatal mouse cochlea. Our results show localization of this gap junction protein to specific cochlear structures, including the
C M, Frenz, T R, Van De Water
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On the modulation of connexin 26 by CO2 [PDF]
The mechanism through which changes in PCO2 in the blood are detected is much disputed. Although many believe the stimulus for CO2 detection to be the associated increase in H+, increasing evidence supports a role for direct CO2 detection. In a recent development, Huckstepp et al demonstrated that connexin 26 hemichannels open in response to elevated ...
Meigh, Louise
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Effects of Testosterone on the Expression of Connexin 26 and Connexin 43 in the Uterus of Rats During Early Pregnancy. [PDF]
In Vivo, 2020 Background/Aim: It was hypothesized that testosterone could affect the distribution and expression of connexin 26 and connexin 43 in the uterus. Thus, the effects of testosterone on these parameters in the uterus during the uterine receptivity period ...
Kamal DAM, Ibrahim SF, Mokhtar MH.
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Hearing impairment in Dutch patients with connexin 26 (GJB2) and connexin 30 (GJB6) mutations [PDF]
International Journal of Pediatric Otorhinolaryngology, 2005 Despite the identification of mutations in the connexin 26 (GJB2) gene as the most common cause of recessive nonsyndromic hearing loss, the pattern of hearing impairment with these mutations remains inconsistent. Recently a deletion encompassing the GJB6 gene was identified and hypothesized to also contribute to hearing loss.
Santos, R.L. +9 more
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[From gene to disease: deafness and connexin 26].
Nederlands tijdschrift voor geneeskunde, 2002 Contains fulltext : 120713.pdf (Publisher’s version ) (Closed access)
Hoefsloot, L.H. +2 more
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