Results 91 to 100 of about 771 (173)

Contryphan-Vn: A modulator of Ca2+-dependent K+ channels

, 2003
Contryphan-Vn is a D-tryptophan-containing disulfide-constrained nonapeptide isolated from the venom of Conus ventricosus, the single Mediterranean cone snail species.
Schininà, Maria Eugenia, PACI, MAURIZIO, Lapied, B, Grolleau, F, Cicero, DO, Grolleau, Francoise, Eliseo, Tommaso, Lapied, Bruno, Paci, M, Raybaudi Massilia, G, Polticelli, F., Molgó, Jordi, Ascenzi, Paolo, Polticelli, F, CICERO, DANIEL OSCAR, Schinina, ME, Polticelli, Fabio, Barbier, Julien, Barbier, J, Ascenzi, P, Eliseo, T, Molgo, J, Bournaud, Roland, Bournaud, R, Massilia, Gabriella Raybaudi   +24 more
core   +1 more source

Isolation, structural identification and biological characterization of two conopeptides from the Conus pennaceus venom

, 2017
A novel anti-mollusk conopeptide pn4c was isolated from the Conus pennaceus venom by repeated HPLC fractionation based on the activity against freshwater snails.
Moustafa Sarhan, Mohamed Abdel-Rahman, Samy Saber, Ryota Okabe, Yoshiaki Nakagawa, Yoshiyuki Ota, Mohammed Abdel-Wahab, Masahiro Miyashita, Hironori Juichi, Maged Fouda   +9 more
core   +1 more source

Proteogenomic Assessment of Intraspecific Venom Variability: Molecular Adaptations in the Venom Arsenal of Conus purpurascens. [PDF]

Mol Cell Proteomics, 2021
Grandal M, Hoggard M, Neely B, Davis WC, Marí F.   +4 more
europepmc   +1 more source

Principal Component and Structural Element Analysis Provide Insights into the Evolutionary Divergence of Conotoxins. [PDF]

Biology (Basel), 2022
Kikuchi AKV, Tayo LL.
europepmc   +1 more source

Proteomic analysis of Red Sea Conus taeniatus venom reveals potential biological applications. [PDF]

J Venom Anim Toxins Incl Trop Dis, 2021
Fouda MMA, Abdel-Wahab M, Mohammadien A, Germoush MO, Sarhan M.   +4 more
europepmc   +1 more source

Pharmacological profiles and anti-inflammatory activity of pCN-diEPP and mCN-diEPP, new alpha9alpha10 nicotinic receptor ligands. [PDF]

Neuropharmacology, 2023
Richter K, Herz SM, Stokes C, Damaj MI, Grau V, Papke RL.   +5 more
europepmc   +1 more source

The Untapped Potential of Cone Snail Venom Peptides: Conopressin’s Modulation of Oxytocin and Vasopressin Hormone Receptors [PDF]

25 pagesThis paper provides a review of the medical and research applications of cone snail venom components. Cone snail venom contains specialized peptides called conopeptides which are estimated to number more than 800,000 in total from across all cone
Ford, Jackson
core   +1 more source

Peptides containing SARS-CoV-2 spike-protein residues are antagonists of α7 and α9α10 nAChRs and modulate interleukin-1β release from human monocytic THP-1 cells. [PDF]

J Biol Chem
Hone AJ, Richter K, Riaz Z, Wakkuri J, Tekarli B, Gajewiak J, Grau V, McIntosh JM.   +7 more
europepmc   +1 more source

Special Issue "Ion Channels as a Therapeutic Target: Drug Design and Pharmacological Investigation 2.0. [PDF]

Int J Mol Sci
Guerrini G, Giovannoni MP.
europepmc   +1 more source

Ancestral Sequence Reconstruction Provides Insights into the Structural Diversification and Neofunctionalization of T-superfamily Conotoxins in Conus. [PDF]

Mol Biol Evol
Espino SS, Koch TL, Gajewiak J, Giglio ML, Watkins M, Safavi-Hemami H, Olivera BM.   +6 more
europepmc   +1 more source