Results 101 to 110 of about 1,314 (186)

Characterization of a Novel Conus bandanus Conopeptide Belonging to the M-Superfamily Containing Bromotryptophan

Marine Drugs, 2014
A novel conotoxin (conopeptide) was biochemically characterized from the crude venom of the molluscivorous marine snail, Conus bandanus (Hwass in Bruguière, 1792), collected in the south-central coast of Vietnam.
Bao Nguyen, Jean-Pierre Le Caer, Gilles Mourier, Robert Thai, Hung Lamthanh, Denis Servent, Evelyne Benoit, Jordi Molgó   +7 more
doaj   +1 more source

Analgesic treatment of ciguatoxin-induced cold allodynia [PDF]

, 2013
Ciguatera, the most common form of nonbacterial ichthyosarcotoxism, is caused by consumption of fish that have bioaccumulated the polyether sodium channel activator ciguatoxin.
Cabot, Peter J., Collins, Lindon S., Deuis, Jennifer R., Inserra, Marco C., Lewis, Richard J., Namer, Barbara, Reeh, Peter W., Vetter, Irina, Zimmermann, Katharina   +8 more
core   +1 more source

Stabilization of a-conotoxin AuIB: influences of disulfide connectivity and backbone cyclization [PDF]

, 2011
a-Conotoxins are peptides isolated from the venom ducts of cone snails that target nicotinic acetylcholine receptors (nAChRs). They are valuable pharmacological tools and have potential applications for treating a range of conditions in humans, including
Adams, DJ, Alvarmo, C, Clark, R, Craik, D, Daly, N, Grishin, A, Gunasekera, S, Lovelace, E, Nevin, S   +8 more
core  

Ohustatud Euroopa naaritsa (Mustela lutreola) sigimine ja käitumine tehiskeskkonnas [PDF]

, 2017
Väitekirja elektrooniline versioon ei sisalda publikatsiooneEuroopa naarits on kriitiliselt ohustatud imetaja, mis on loodusest kadumas. Päästmaks liiki väljasuremisest hakati naaritsaid pidama loomaaedades. Vangistuses on loomade paljundamine keeruline,
Kiik, Kairi
core  

Conotoxins: structure, therapeutic potential and pharmacological applications. [PDF]

, 2016
Cone snails, also known as marine gastropods, from Conus genus produce in their venom a diverse range of small pharmacologically active structured peptides called conotoxins.
Kamal, M., Kamal, M., Karim, S., Karim, S., Mir, R., Mir, R., Mirza, Z., Mirza, Z., Wilson, C., Wilson, C.   +9 more
core   +2 more sources

Recombinant Expression and Characterization of α-Conotoxin LvIA in Escherichia coli

Marine Drugs, 2016
α-Conotoxin LvIA is derived from Conus lividus, native to Hainan, and is the most selective inhibitor of α3β2 nicotinic acetylcholine receptors (nAChRs) known to date.
Xiaopeng Zhu, Jianpeng Bi, Jinpeng Yu, Xiaodan Li, Yaning Zhang, Dongting Zhangsun, Sulan Luo   +6 more
doaj   +1 more source

‘Messy’ Processing of χ-conotoxin MrIA Generates Homologues with Reduced hNET Potency

Marine Drugs, 2019
Integrated venomics techniques have shown that variable processing of conotoxins from Conus marmoreus resulted in a dramatic expansion in the number of expressed conotoxins. One conotoxin from C.
Rebekah Ziegman, Andreas Brust, Prerna Jha, Fernanda C. Cardoso, Richard J. Lewis, Paul F. Alewood   +5 more
doaj   +1 more source

Mining Invertebrate Natural Products for Future Therapeutic Treasure

Natural Product Communications, 2011
This review focuses on biologically active entities from invertebrate sources, especially snails. The reader will encounter several categories of compounds from snails including glycosaminoglycans, peptides, proteins (glycoproteins), and enzymes which ...
Youmie Park
doaj   +1 more source

Influence of Disulfide Connectivity on Structure and Bioactivity of α-Conotoxin TxIA

Molecules, 2014
Cone snails express a sophisticated arsenal of small bioactive peptides known as conopeptides or conotoxins (CTxs). Through evolutionary selection, these peptides have gained the ability to interact with a range of ion channels and receptors, such as ...
Yong Wu, Xiaosa Wu, Jinpeng Yu, Xiaopeng Zhu, Dongting Zhangsun, Sulan Luo   +5 more
doaj   +1 more source

Cone Snail Broad-Transcriptomics Elucidate the Evolutionary Diversification and Anti-Microbial Potential of Conopeptides

Journal of Marine Science and Engineering
Conus venoms are both highly powerful and complex, exhibiting a remarkably intriguing molecular variability. The biologic reasons behind such astonishing molecular diversity are yet to be fully understood.
José Morim, Yihe Zhao, Lei Huang, Agostinho Antunes   +3 more
doaj   +1 more source