Results 101 to 110 of about 21,330 (214)
Toxins, 2018 Mycobacterium tuberculosis is the etiological agent of tuberculosis, an airborne infectious disease that is a leading cause of human morbidity and mortality worldwide.
Andrea Figueroa-Montiel +5 more
doaj +1 more source
Residues Responsible for the Selectivity of α-Conotoxins for Ac-AChBP or nAChRs
Marine Drugs, 2016 Nicotinic acetylcholine receptors (nAChRs) are targets for developing new drugs to treat severe pain, nicotine addiction, Alzheimer disease, epilepsy, etc. α-Conotoxins are biologically and chemically diverse. With 12–19 residues and two disulfides, they
Bo Lin, Shihua Xiang, Mengsen Li
doaj +1 more source
Omega-Conotoxin prevents the effect of adrenocorticotropin in hypovolemic shock
, 1992 Omega-Conotoxin prevents the effect of adrenocorticotropin in hypovolemic ...
BAZZANI, Carla +2 more
core
Properties of ω conotoxin MVIIC receptors associated with α1A calcium channel subunits in rat brain
, 1995 Solubilized 125I-ω conotoxin MVIIC receptors from rat cerebellum were immunoprecipitated by antibodies directed against the calcium channel α1A subunit.
Leveque, Christian +5 more
core +1 more source
Stability and Structure-Forming Properties of the Two Disulfide Bonds of α-Conotoxin GI
, 2016 α-Conotoxin GI is a 13 residue snail toxin peptide cross-linked by Cys2−Cys7 and Cys3−Cys13 disulfide bridges. The formation of the two disulfide bonds by thiol/disulfide exchange with oxidized glutathione (GSSG) has been characterized.
Andreas Kaerner (2140825) +1 more
core +1 more source
, 2018 To expand our capacity to discover venom sequences from the genomes of venomous organisms, we applied targeted sequencing techniques to selectively recover venom gene superfamilies and non-toxin loci from the genomes of 32 cone snail species (family ...
Phuong, Mark A., Mahardika, Gusti N.
core +1 more source
Identification of “alpha-conotoxin-like” Peptide in Conus pennaceus Born, 1778, Venom [PDF]
بومشناسی آبزیان, 2018 Conic snails are slow-moving carnivorous that use a very powerful venom to hunt. This venom is a combination of different toxins from the family of conototoxins.
Hadi Dehghani +4 more
doaj
Discovery of novel conotoxin candidates using machine learning
, 2018 Cone snails (genus ) are venomous marine snails that inject prey with a lethal cocktail of conotoxins, small, secreted, and cysteine-rich peptides.
Samuel D. Robinson +10 more
core +1 more source
Refolding of omega conotoxin peptide derived from marine snail, Conus magus, to evaluate its analgesic effects [PDF]
, 2015 Oxidative refolding is one of the key challenges hampering the development of peptide based compounds as therapeutics. The correct refolding for three disulfide peptide like w-Conotoxi n MVIIA is difficult and crucial for biological activity.
Eisapoor, Seyed Sahand
core +1 more source
Solution structure of μ-conotoxin GIIIA analysed by 2D-NMR and distance geometry calculations
, 1991 We have investigated the structure of μ-conotoxin GIIIA by 2D-NMR methods. The assignment of 1H NMR spectra and a quantitative analysis of NOE and J-coupling data are presented.
Becker, Stefan +11 more
core +1 more source