Results 41 to 50 of about 3,898 (208)

High-Throughput Prediction and Design of Novel Conopeptides for Biomedical Research and Development

open access: yesBioDesign Research, 2022
Cone snail venoms have been considered a valuable treasure for international scientists and businessmen, mainly due to their pharmacological applications in development of marine drugs for treatment of various human diseases.
Bingmiao Gao   +7 more
doaj   +1 more source

The composition of phosphate granules in the digestive glands of marine prosobranch gastropods: variation in relation to taxonomy [PDF]

open access: yes, 1998
The composition of some 1150 phosphate granules in the digestive glands of over 40 species of marine prosobranch gastropods has been surveyed using a simple preparation technique and semiquantitative SEM x-ray microanalysis. Spectral peaks for Mg, K, Ca,
Bebianno, Maria João   +3 more
core   +1 more source

Conus vexillum venom induces oxidative stress in Ehrlich's ascites carcinoma cells: an insight into the mechanism of induction

open access: yesJournal of Venomous Animals and Toxins including Tropical Diseases, 2013
Background It is estimated that venoms of marine cone snails (genus Conus) contain more than 100,000 different small peptides with a wide range of pharmacological and biological actions.
Mohamed A Abdel-Rahman   +4 more
doaj   +1 more source

High-throughput prediction and characterization of antimicrobial peptides from multi-omics datasets of Chinese tubular cone snail (Conus betulinus)

open access: yesFrontiers in Marine Science, 2022
Individual cone snail (Conus sp.) contains thousands of bioactive peptides, but there are limited studies on its antimicrobial peptides (AMPs). Here, we investigated AMPs along with AMP-derived genes in the representative Chinese tubular cone snail (C ...
Ruihan Li   +16 more
doaj   +1 more source

Characterization of the venom of the vermivorous cone snail Conus fulgetrum [PDF]

open access: yesBioscience, Biotechnology, and Biochemistry, 2016
Abstract Over 200 components with molecular mass ranging mainly from 400 to 4000 Da were characterized from the venom of the vermivorous cone snail Conus fulgetrum that inhabit Egyptian Red Sea. One major component having a molecular mass of 2946 Da was purified by HPLC, and its primary structure was determined by a combination of Edman ...
Mohammed, Abdel-Wahab   +8 more
openaire   +2 more sources

Beyond Conus: Phylogenetic relationships of Conidae based on complete mitochondrial genomes [PDF]

open access: yes, 2017
Understanding how the extraordinary taxonomic and ecological diversity of cone snails (Caenogastropoda: Conidae) evolved requires a statistically robust phylogenetic framework, which thus far is not available. While recent molecular phylogenies have been
Puillandre, Nicolas   +2 more
core   +2 more sources

Three New Cytotoxic Steroidal Glycosides Isolated from Conus pulicarius Collected in Kosrae, Micronesia

open access: yesMarine Drugs, 2017
Three new sulfated steroidal glycosides (3–5), along with known cholesterol derivatives (1,2), were isolated from the visceral extract of the cone snail Conus pulicarius.
Yeon-Ju Lee   +6 more
doaj   +1 more source

Combined Proteotranscriptomic-Based Strategy to Discover Novel Antimicrobial Peptides from Cone Snails

open access: yesBiomedicines, 2021
Despite their impressive diversity and already broad therapeutic applications, cone snail venoms have received less attention as a natural source in the investigation of antimicrobial peptides than other venomous animals such as scorpions, spiders, or ...
Anicet Ebou   +4 more
doaj   +1 more source

Screening and Validation of Highly-Efficient Insecticidal Conotoxins from a Transcriptome-Based Dataset of Chinese Tubular Cone Snail

open access: yesToxins, 2017
Most previous studies have focused on analgesic and anti-cancer activities for the conotoxins identified from piscivorous and molluscivorous cone snails, but little attention has been devoted to insecticidal activity of conotoxins from the dominant ...
Bingmiao Gao   +5 more
doaj   +1 more source

Proteomic analysis of Red Sea Conus taeniatus venom reveals potential biological applications

open access: yesJournal of Venomous Animals and Toxins including Tropical Diseases, 2021
Background: Diverse and unique bioactive neurotoxins known as conopeptides or conotoxins are produced by venomous marine cone snails. Currently, these small and stable molecules are of great importance as research tools and platforms for discovering new ...
Maged M. A. Fouda   +4 more
doaj   +1 more source

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