Results 91 to 100 of about 6,856,628 (321)

CD137L-stimulated dendritic cells are more potent than conventional dendritic cells at eliciting cytotoxic T-cell responses [PDF]

OncoImmunology, 2013
Dendritic cells (DCs) are highly potent initiators of adaptive immune responses and, as such, represent promising tools for immunotherapeutic applications. Despite their potential, the current efficacy of DC-based immunotherapies is poor. CD137 ligand (CD137L) signaling has been used to derive a novel type of DCs from human peripheral blood monocytes ...
Zulkarnain, Harfuddin, Shaqireen, Kwajah, Adrian, Chong Nyi Sim, Paul Anthony, Macary, Herbert, Schwarz   +4 more
openaire   +2 more sources

Quantitative MRI Uncovers Subtle Cortical Damage in Myelin Oligodendrocyte Glycoprotein Antibody‐Associated Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To determine whether myelin‐sensitive quantitative MRI reveals microstructural abnormalities in normal‐appearing cortex (NACtx) in myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD), indicating that conventional MRI underestimates remission residual cortical injury.
Valentina Camera, Agnese Tamanti, Silvia Messina, Nicola Dall'Osto, Teresa Maltempo, Stefano Ziccardi, Matteo Foschi, Maria Grazia Piscaglia, Diana Ferraro, Francesco Crescenzo, Francesca Rossi, Albulena Bajrami, Sabrina Marangoni, Damiano Marastoni, Francesca Benedetta Pizzini, Maria Isabel Leite, Roberta Magliozzi, Patrick Waters, Massimiliano Calabrese, Jacqueline Palace, Ruth Geraldes   +20 more
wiley   +1 more source

EFFECT OF DNA CONSTRUCTIONS ELECTROPORATION ON DENDRITIC CELLS

Медицинская иммунология, 2021
Today transfection of mammalian cell with DNA or RNA construction is the only method for delivering programmed information into the cell nucleus. Electroporation is most commonly used method of transfection in experiments with dendritic cell.
A. S. Bulygin, V. P. Tereshchenko, R. Yu. Zavodskii, I. A. Obleukhova, S. V. Sennikov, A. N. Silkov   +5 more
doaj   +1 more source

Electrochemical Behavior of Flame‐Sprayed Sc‐Doped AlCoCrFeMo High‐Entropy Alloy Coatings in 3.5% Sodium Chloride Solution

Advanced Engineering Materials, EarlyView.
Scandium (Sc)‐doped AlCoCrFeMo HEA coatings are fabricated via flame spraying with 0.1, 0.3, and 0.5 wt% Sc additions. Among these, the HEA‐Sc0.3 coating exhibits the highest corrosion resistance, indicated by a more positive corrosion potential and lower current density.
Pankaj Kumar, Akash Vyas, Mohammad Aatif Qazi, Nashit Jalal, Maria Ophelia Jarligo, Mostafa Yakout, Jing Liu, André McDonald   +7 more
wiley   +1 more source

Effective cancer immunotherapy by natural mouse conventional type-1 dendritic cells bearing dead tumor antigen

Journal for ImmunoTherapy of Cancer, 2019
Background The manipulation of dendritic cells (DCs) for cancer vaccination has not reached its full potential, despite the revolution in cancer immunotherapy.
Stefanie K. Wculek, Joaquín Amores-Iniesta, Ruth Conde-Garrosa, Sofía C. Khouili, Ignacio Melero, David Sancho   +5 more
doaj   +1 more source

Development of Pig Conventional Dendritic Cells From Bone Marrow Hematopoietic Cells in vitro

Frontiers in Immunology, 2020
In recent years, porcine dendritic cells (DCs) have been identified from pig tissues. However, studying the interaction of porcine DCs with pathogens is still difficult due to the scarcity of DCs in tissues.
Yanli Li, Lucinda Puebla-Clark, Jesús Hernández, Ivan Díaz, Enric Mateu, Enric Mateu   +5 more
doaj   +1 more source

Probing Host Pathogen Cross-Talk by Transcriptional Profiling of Both Mycobacterium tuberculosis and Infected Human Dendritic Cells and Macrophages. [PDF]

, 2008
BACKGROUND: Transcriptional profiling using microarrays provides a unique opportunity to decipher host pathogen cross-talk on the global level. Here, for the first time, we have been able to investigate gene expression changes in both Mycobacterium ...
Waddell, Simon, Castagnoli, PR, Mattia Pelizzola (20247), Castagnoli, Paola Ricciardi, Pelizzola Mattia, Foti, M, Maria Foti, Butcher, Philip, Neyrolles, Olivier, Neyrolles, O, Antoine Tanne, Simon J Waddell, Olivier Neyrolles, Pelizzola, M, Tailleux, L, Simon J. Waddell, Antoine Tanne (272975), Philip D Butcher (16047203), Maria Foti (20249), Neil G. Stoker, Stoker Neil G., Waddell, SJ, Tailleux Ludovic, Tailleux, Ludovic, Gicquel, Brigitte, Simon Waddell (4462816), Castagnoli Paola Ricciardi, Brigitte Gicquel, Philip D Butcher, Tanne Antoine, Alessandra Mortellaro (272973), Mortellaro, A, Gicquel Brigitte, Stoker, Neil, Philip D. Butcher, Butcher, PD, Tanne, Antoine, Olivier Neyrolles (72204), Tanne, A, Mortellaro, Alessandra, Paola Ricciardi Castagnoli (16048310), Ludovic Tailleux, Michael Withers (272974), Neyrolles Olivier, Withers Michael, Foti, Maria, Waddell Simon J., Stoker, NG, Michael Withers, Pelizzola, Mattia, Mortellaro Alessandra, Brigitte Gicquel (31454), Ludovic Tailleux (72195), Neil G Stoker (16048313), Alessandra Mortellaro, Neil G Stoker, Foti Maria, Gicquel, B, Butcher Philip D., Withers, M, Mattia Pelizzola, Paola Ricciardi Castagnoli, Withers, Michael   +62 more
core   +1 more source

T Follicular Helper, but Not Th1, Cell Differentiation in the Absence of Conventional Dendritic Cells [PDF]

The Journal of Immunology, 2015
Abstract Development of long-lived humoral immunity is dependent on CXCR5-expressing T follicular helper (Tfh) cells, which develop concomitantly to effector Th cells that support cellular immunity. Conventional dendritic cells (cDCs) are critical APCs for initial priming of naive CD4+ T cells but, importantly, also provide accessory ...
Madelene W, Dahlgren, Tobias, Gustafsson-Hedberg, Megan, Livingston, Helena, Cucak, Samuel, Alsén, Ulf, Yrlid, Bengt, Johansson-Lindbom   +6 more
openaire   +2 more sources

Controlling Grain Growth in Powder Bed Fusion of Yttria‐Stabilized Zirconia Using Femtosecond Lasers: Challenges and Methodological Insights

Advanced Engineering Materials, EarlyView.
Binder‐free laser powder bed fusion of 8YSZ with a femtosecond laser is used to map process windows linking scan strategy, heat accumulation, and grain growth. Time‐resolved thermography and simulations reveal thermal regimes that enable continuous, vitrified, and fine‐grained 8YSZ surface layers without absorptive additives and demonstrate ...
Markus Kühn, Sarah Kaden, Andrea Barz, Daniel Störzner, Jens Bliedtner, Andrés Fabián Lasagni   +5 more
wiley   +1 more source

Migratory CD11b+ conventional dendritic cells induce T follicular helper cell–dependent antibody responses

Science immunology, 2017
Conventional DC2s are necessary and sufficient for priming T follicular helper cells. Priming T follicular helper cells T follicular helper (Tfh) cells play an important role in modulating antibody production by B cells. Here, Krishnaswamy et al.
J. K. Krishnaswamy, U. Gowthaman, Bi-Yan Zhang, J. Mattsson, L. Szeponik, Dong Liu, Renee Wu, Theresa White, Samuele Calabro, Lan Xu, Magalie A. Collet, M. Yurieva, S. Alsén, P. Fogelstrand, A. Walter, W. Heath, Scott N. Mueller, U. Yrlid, Adam Williams, S. Eisenbarth   +19 more
semanticscholar   +1 more source