Results 81 to 90 of about 121,661 (250)

A hepatic network of dendritic cells mediates CD4 T cell help outside lymphoid organs

Nature Communications
While CD4+ T cells are a prerequisite for CD8+ T cell-mediated protection against intracellular hepatotropic pathogens, the mechanisms facilitating the transfer of CD4-help to intrahepatic CD8+ T cells are unknown.
Kieran English, Rain Kwan, Lauren E. Holz, Claire McGuffog, Jelte M. M. Krol, Daryan Kempe, Tsuneyasu Kaisho, William R. Heath, Leszek Lisowski, Maté Biro, Geoffrey W. McCaughan, David G. Bowen, Patrick Bertolino   +12 more
doaj   +1 more source

Fatal COVID-19 is Associated with Reduced HLA-DR, CD123 or CD11c Expression on Circulating Dendritic Cells

Journal of Inflammation Research, 2022
Amal Hasan,1 Ebaa Al-Ozairi,2,3 Nosiba YM Hassan,4 Shamsha Ali,5 Rasheed Ahmad,1 Nada Al-Shatti,6 Salem Alshemmari,3,7 Fahd Al-Mulla8 1Department of Immunology and Microbiology, Dasman Diabetes Institute, Dasman, Kuwait City, Kuwait; 2Clinical Research ...
Hasan A, Al-Ozairi E, Hassan NYM, Ali S, Ahmad R, Al-Shatti N, Alshemmari S, Al-Mulla F   +7 more
doaj  

Essential functions of Runx/Cbfβ in gut conventional dendritic cells for priming Rorγt + T cells

Life Science Alliance, 2020
Loss of Runx/Cbfβ complexes during DC development leads to a loss of gut CD103 + CD11b + cDC2s, which was accompanied with impaired differentiation of both Rorγt + Th17 cells and type 3 Rorγt + Treg cells.
Mari Tenno, Alicia Yoke Wei Wong, Mika Ikegaya, Eiji Miyauchi, Wooseok Seo, Peter See, Tamotsu Kato, Takashi Taida, Michiko Ohno-Oishi, Hiroshi Ohno, Hideyuki Yoshida, Florent Ginhoux, Ichiro Taniuchi   +12 more
doaj   +1 more source

Biomineral‐Inspired Organic/Inorganic Colloidal Liquid‐Crystalline Hybrids for Photoresponsive Adhesion

Advanced Functional Materials, EarlyView.
A new class of photoresponsive liquid‐crystalline (LC) adhesives based on biomineral‐inspired organic/inorganic colloidal hybrids is reported. These colloidal LC materials are formed by hybridization of a hydroxyapatite nanorod with azobenzene‐based forklike molecules.
Junya Uchida, Ryuta Kiguchi, Riki Kato, Yuta Nishina, Takashi Kato   +4 more
wiley   +1 more source

Endothelial cell-derived microparticles induce plasmacytoid dendritic cell maturation: potential implications in inflammatory diseases

Haematologica, 2009
Background Increased circulating endothelial microparticles, resulting from vascular endothelium dysfunction, and plasmacytoid dendritic cell activation are both encountered in common inflammatory disorders.
Fanny Angelot, Estelle Seillès, Sabeha Biichlé, Yael Berda, Béatrice Gaugler, Joel Plumas, Laurence Chaperot, Françoise Dignat-George, Pierre Tiberghien, Philippe Saas, Francine Garnache-Ottou   +10 more
doaj   +1 more source

Mitigating Concentration Polarization in Dry‐Processed Ultra‐Thick Cathodes Using a Low‐Viscosity Electrolyte With Soft Li+ Solvation

Advanced Functional Materials, EarlyView.
A low‐viscosity, soft‐solvating methyl ethanoate (ME)‐based electrolyte facilitates electrolyte infiltration into dense dry‐processed ultra‐thick NCM622 cathodes while reducing Li+ desolvation barriers at Li‐metal anodes. Balanced cathode‐scale ion transport and anode‐side interfacial kinetics mitigate concentration polarization and interfacial ...
Jae Bin Park, Yewon Park, Ah Reum Choi, Chaerin Park, Seonhee Jo, Seongwook Chae, Taekyun Kwon, Ji‐Oh Kim, Ji‐Hoon Baik, Sung Hyun Kwon, Minjoon Park, Jin Hong Lee   +11 more
wiley   +1 more source

Atomically Dispersed Ni Site Catalysts Accelerating Sluggish Sulfur Redox Kinetics in Nonaqueous Zn‐S Batteries

Advanced Functional Materials, EarlyView.
An atomically dispersed Ni catalyst featuring Ni‐N4 coordination is developed as a sulfur host for nonaqueous Zn─S batteries. This configuration modulates the electronic structure to lower activation barriers during rate‐limiting steps and promotes a robust ZnF2‐rich cathode‐electrolyte interphase, thereby accelerating sulfur redox kinetics ...
Junhyuk Ji, Dongwoo Kim, Nuri Moon, Daehwan Kim, Keon Kim, Nahyung Kim, Young Yong Kim, Won Bae Kim   +7 more
wiley   +1 more source

Langerin+CD8+ Dendritic Cells in the Splenic Marginal Zone: Not So Marginal After All

Frontiers in Immunology, 2019
Dendritic cells (DC) fulfill an essential sentinel function within the immune system, acting at the interface of innate and adaptive immunity. The DC family, both in mouse and man, shows high functional heterogeneity in order to orchestrate immune ...
Ronald A. Backer, Nathalie Diener, Björn E. Clausen   +2 more
doaj   +1 more source

Gardiquimod Nanoemulsion Targets Cutaneous Leishmaniasis Lesions Reducing Systemic Toxicity and Parasite Burden

Advanced Healthcare Materials, EarlyView.
Nanoemulsion delivery of a TLR7 agonist enhances safety and promotes colocalization with Leishmania‐infected macrophages in skin lesions, enabling a ∼2‐log reduction in parasite burden. However, tissue‐level constraints and TLR‐driven regulatory feedback generate a mixed immune response that limits complete parasite clearance.
Carmen Palomino‐Cano, M. Carmen Mera‐Delgado, Esther Moreno, Esther Larrea, Lecnia Aguirre, Jonathan Miguel Zanatta, Sónia Barros‐Carvalho, Iola F. Duarte, Ricardo Silvestre, Juan M. Irache, Javier Carrión, Socorro Espuelas   +11 more
wiley   +1 more source

Regulatory T cells diminish transmission of HIV from Dendritic cells to conventional CD4+ T cells

Frontiers in Immunology, 2014
Formation of immunological synapses between dendritic cells (DC) and conventional CD4+ T cells (Tcon) is critical for productive immune responses. However, when DCs are HIV-infected such synapses are critical to establish HIV infection.
Maria Eugenia Moreno-Fernandez, Maria Eugenia Moreno-Fernandez, Jara J Joedicke, Claire Anne Chougnet   +3 more
doaj   +1 more source