Results 61 to 70 of about 6,907,839 (294)

Quantitative MRI Uncovers Subtle Cortical Damage in Myelin Oligodendrocyte Glycoprotein Antibody‐Associated Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To determine whether myelin‐sensitive quantitative MRI reveals microstructural abnormalities in normal‐appearing cortex (NACtx) in myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD), indicating that conventional MRI underestimates remission residual cortical injury.
Valentina Camera   +20 more
wiley   +1 more source

Postnatal development of dendritic calcium signaling in rat hippocampal pyramidal cells [PDF]

open access: yes, 2013
In CA1 pyramidal neurons, dendritic calcium transients in stratum radiatum were evoked in acute slices via backpropagating action potentials using patch clamp recordings.
Pohle, Jörg
core   +1 more source

The Role of Tolerogenic Dendritic Cell Therapy in Autoimmune Diseases

open access: yesمجله دانشکده پزشکی اصفهان, 2018
Dendritic cells (DCs) are special antigen-presenting cells that are important for activation of immune response and tolerance. Dendritic cells have been divided in two subtypes of conventional and plasmacytoid dendritic cells.
Maryam Shahidi   +3 more
doaj   +1 more source

IRF8-Dependent Type I Conventional Dendritic Cells (cDC1s) Control Post-Ischemic Inflammation and Mildly Protect Against Post-Ischemic Acute Kidney Injury and Disease

open access: yesFrontiers in Immunology, 2021
Post-ischemic acute kidney injury and disease (AKI/AKD) involve acute tubular necrosis and irreversible nephron loss. Mononuclear phagocytes including conventional dendritic cells (cDCs) are present during different phases of injury and repair, but the ...
Na Li   +12 more
doaj   +1 more source

TGF-β1 Accelerates Dendritic Cell Differentiation from Common Dendritic Cell Progenitors and Directs Subset Specification toward Conventional Dendritic Cells [PDF]

open access: yesThe Journal of Immunology, 2010
Abstract Dendritic cells (DCs) in lymphoid tissue comprise conventional DCs (cDCs) and plasmacytoid DCs (pDCs) that develop from common DC progenitors (CDPs). CDPs are Flt3+c-kitintM-CSFR+ and reside in bone marrow. In this study, we describe a two-step culture system that recapitulates DC development from c-kithiFlt3−/lo multipotent ...
Piritta, Felker   +6 more
openaire   +2 more sources

Electrochemical Behavior of Flame‐Sprayed Sc‐Doped AlCoCrFeMo High‐Entropy Alloy Coatings in 3.5% Sodium Chloride Solution

open access: yesAdvanced Engineering Materials, EarlyView.
Scandium (Sc)‐doped AlCoCrFeMo HEA coatings are fabricated via flame spraying with 0.1, 0.3, and 0.5 wt% Sc additions. Among these, the HEA‐Sc0.3 coating exhibits the highest corrosion resistance, indicated by a more positive corrosion potential and lower current density.
Pankaj Kumar   +7 more
wiley   +1 more source

Genome Wide Transcriptome Analysis of Dendritic Cells Identifies Genes with Altered Expression in Psoriasis [PDF]

open access: yes, 2013
Activation of dendritic cells by different pathogens induces the secretion of proinflammatory mediators resulting in local inflammation. Importantly, innate immunity must be properly controlled, as its continuous activation leads to the development of ...
Szász, András   +27 more
core   +2 more sources

CD137L-stimulated dendritic cells are more potent than conventional dendritic cells at eliciting cytotoxic T-cell responses [PDF]

open access: yesOncoImmunology, 2013
Dendritic cells (DCs) are highly potent initiators of adaptive immune responses and, as such, represent promising tools for immunotherapeutic applications. Despite their potential, the current efficacy of DC-based immunotherapies is poor. CD137 ligand (CD137L) signaling has been used to derive a novel type of DCs from human peripheral blood monocytes ...
Zulkarnain, Harfuddin   +4 more
openaire   +2 more sources

Controlling Grain Growth in Powder Bed Fusion of Yttria‐Stabilized Zirconia Using Femtosecond Lasers: Challenges and Methodological Insights

open access: yesAdvanced Engineering Materials, EarlyView.
Binder‐free laser powder bed fusion of 8YSZ with a femtosecond laser is used to map process windows linking scan strategy, heat accumulation, and grain growth. Time‐resolved thermography and simulations reveal thermal regimes that enable continuous, vitrified, and fine‐grained 8YSZ surface layers without absorptive additives and demonstrate ...
Markus Kühn   +5 more
wiley   +1 more source

Effective cancer immunotherapy by natural mouse conventional type-1 dendritic cells bearing dead tumor antigen

open access: yesJournal for ImmunoTherapy of Cancer, 2019
Background The manipulation of dendritic cells (DCs) for cancer vaccination has not reached its full potential, despite the revolution in cancer immunotherapy.
Stefanie K. Wculek   +5 more
doaj   +1 more source

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