Results 51 to 60 of about 6,856,628 (321)

In Vivo Induction of Immune Responses to Pathogens by Conventional Dendritic Cells [PDF]

Immunity, 2008
Specific defense mechanisms against pathogens are fulfilled by different subsets of nonmucosal conventional dendritic cells (DCs), including migratory Langerhans cells (LCs), dermal DCs, and resident CD8(+) and CD8(-) DCs found in lymphoid organs. Dermal DCs capture antigens in the skin and migrate to lymph nodes, where they can transfer the antigens ...
López-Bravo, María, Ardavín, Carlos
openaire   +3 more sources

Peripheral CD103+ dendritic cells form a unified subset developmentally related to CD8α+ conventional dendritic cells [PDF]

Journal of Experimental Medicine, 2010
Although CD103-expressing dendritic cells (DCs) are widely present in nonlymphoid tissues, the transcription factors controlling their development and their relationship to other DC subsets remain unclear. Mice lacking the transcription factor Batf3 have a defect in the development of CD8α+ conventional DCs (cDCs) within lymphoid tissues.
Edelson, Brian T, KC, Wumesh, Juang, Richard, Kohyama, Masako, Benoit, Loralyn A, Klekotka, Paul A, Moon, Clara, Albring, Jörn C, Ise, Wataru, Michael, Drew G, Bhattacharya, Deepta, Stappenbeck, Thaddeus S, Holtzman, Michael J, Sung, Sun-Sang J, Murphy, Theresa L, Hildner, Kai, Murphy, Kenneth M   +16 more
openaire   +3 more sources

Bluetongue Virus Targets Conventional Dendritic Cells in Skin Lymph [PDF]

Journal of Virology, 2009
ABSTRACTBluetongue virus (BTV) is the etiological agent of bluetongue, a hemorrhagic disease of ruminants (particularly sheep), which causes important economic losses around the world. BTV is transmitted primarily via the bites of infected midges, which inject the virus into the ruminant's skin during blood feeding.
Hemati, Behzad, Contreras, Vanessa, Urien, Celine, Bonneau, Michel, Takamatsu, Haru-Hisa, Mertens, Peter P.C., Breard, Emmanuel, Sailleau, Corinne, Zientara, Stéphan, Schwartz-Cornil, Isabelle   +9 more
openaire   +4 more sources

Migratory conventional dendritic cells in the induction of peripheral T cell tolerance [PDF]

Journal of Leukocyte Biology, 2013
ABSTRACTConventional DCs are an extremely heterogeneous cell population that comprises several different subsets. A major distinction can be made between lymphoid-resident DCs that are present in the lymphoid tissues and the blood and migratory DCs that reside in the nonlymphoid tissues and migrate to the lymph nodes, both in homeostatic conditions and
Achille, Broggi, Ivan, Zanoni, Francesca, Granucci   +2 more
openaire   +2 more sources

In Vitro and In Vivo Effects of Ketamine on Generation and Function of Dendritic Cells

Journal of Pharmacological Sciences, 2011
.: The question about how intravenous anesthetic reagents affect the development and function of dendritic cell subsets still has no comprehensive answers.
Jingxian Zeng, Shuxuan Xia, Wa Zhong, Jie Li, Liling Lin   +4 more
doaj   +1 more source

Semaphorin 3E deficiency dysregulates dendritic cell functions: In vitro and in vivo evidence.

PLoS ONE, 2021
Regulation of dendritic cell functions is a complex process in which several mediators play diverse roles as a network in a context-dependent manner. The precise mechanisms underlying dendritic cell functions have remained to be addressed.
Hesam Movassagh, Lianyu Shan, Latifa Koussih, Abdulaziz Alamri, Nazila Ariaee, Sam K P Kung, Abdelilah S Gounni   +6 more
doaj   +1 more source

Immunostimulatory conventional dendritic cells evolve into regulatory macrophage-like cells [PDF]

Blood, 2012
AbstractDendritic cell (DC) homeostasis in peripheral tissues reflect a balance between DC generation, migration, and death. The current model of DC ontogeny indicates that pre-cDCs are committed to become terminal conventional DCs (cDCs). Here, we report the unexpected finding that proliferating immunostimulatory CD11c+ MHC class II+ cDCs derived from
Jun, Diao, Anastassia, Mikhailova, Michael, Tang, Hongtao, Gu, Jun, Zhao, Mark S, Cattral   +5 more
openaire   +2 more sources

Human anogenital monocyte-derived dendritic cells and langerin+cDC2 are major HIV target cells

Nature Communications, 2021
Epithelial tissue mononuclear phagocytes (MNP) can transmit HIV to CD4 T cells, but less is known about sub-epithelial cells. Here, the authors describe MNPs in human anogenital and colorectal tissues and find that CD14+CD1c+ monocyte-derived dendritic ...
Jake W. Rhodes, Rachel A. Botting, Kirstie M. Bertram, Erica E. Vine, Hafsa Rana, Heeva Baharlou, Peter Vegh, Thomas R. O’Neil, Anneliese S. Ashhurst, James Fletcher, Grant P. Parnell, J. Dinny Graham, Najla Nasr, Jake J. K. Lim, Laith Barnouti, Peter Haertsch, Martijn P. Gosselink, Angelina Di Re, Faizur Reza, Grahame Ctercteko, Gregory J. Jenkins, Andrew J. Brooks, Ellis Patrick, Scott N. Byrne, Eric Hunter, Muzlifah A. Haniffa, Anthony L. Cunningham, Andrew N. Harman   +27 more
doaj   +1 more source

Vaccine efficacy against primary and metastatic cancer with in vitro-generated CD103+ conventional dendritic cells

Journal for ImmunoTherapy of Cancer, 2020
Background Type 1 conventional dendritic cells (cDC1s) possess efficient antigen presentation and cross-presentation activity, as well as potent T cell priming ability.
Yifan Zhou, N. Slone, Taylor T. Chrisikos, O. Kyrysyuk, Rachel L. Babcock, Yusra B Medik, Haiyan S Li, E. Kleinerman, S. Watowich   +8 more
semanticscholar   +1 more source

Subsets of migrating intestinal dendritic cells [PDF]

, 2010
Dendritic cells (DCs) in the intestine are heterogeneous. Phenotypically different populations of conventional DCs have been identified in the intestinal lamina propria, Peyer's patches, and in the draining mesenteric lymph nodes, to which these DCs ...
Yrlid, Ulf, Cerovic, Vuk, MacPherson, Gordon, Milling, Simon, Yrlid, Ulf,   +4 more
core   +1 more source