The Generation of Plasmacytoid and Conventional Dendritic Cells with M-CSF
2009Mice lacking the ligand for Flt-3 (CD135) have a massive deficit of dendritic cells (DC) in all organs. This phenotype of FL (FL) knockout mice suggested that FL was the archetypal DC poietin in the steady state. However, FL knockout mice also have reduced numbers of common lymphoid progenitors (CLP) and common myeloid progenitors (CMP) so it is ...
Meredith, O'Keeffe +2 more
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Isolation of Conventional Dendritic Cells from Mouse Lungs
2016The lungs are in direct contact with the environment. Separated only by a thin layer of mucosa, the lung immune system is being exposed to dangers like pathogens, allergens, or pollutants. The lung dendritic cells form an elaborate network at the basolateral side of the epithelium and continuously sample antigens from the airway lumen. The conventional
Lianne, van de Laar +2 more
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Tissue-Specific Diversity and Functions of Conventional Dendritic Cells
2017Dendritic cells (DCs) are versatile controllers of immunity, which sense infection or tissue damage and, accordingly, initiate innate and adaptive effector responses. In recent years, it has become evident that DCs exist as an independent hematopoietic lineage comprising several developmentally distinct and functionally specialized subsets that are ...
Dalia, Pakalniškytė +1 more
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Phenotype and functions of conventional dendritic cells are not compromised in aged mice
Immunology & Cell Biology, 2012Aging has profound effects on the immune system, including thymic involution, reduced diversity of the T cell receptor repertoire, reduced effector T cell and B cell function and chronic increase of proinflammatory cytokine production by innate immune cells. The precise effects of aging on conventional dendritic cells (cDC), the main antigen presenting
Sioh-Yang, Tan +5 more
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Reclassification of Plasmacytoid Dendritic Cells as Innate Lymphocytes Is Premature
Nature Reviews Immunology, 2023Marco Colonna +2 more
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Reply to ‘Reclassification of Plasmacytoid Dendritic Cells as Innate Lymphocytes Is Premature’
Nature Reviews Immunology, 2023Florent Ginhoux +2 more
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Reclassifying Plasmacytoid Dendritic Cells as Innate Lymphocytes
Nature Reviews Immunology, 2023Florent Ginhoux +2 more
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Clonal Lineage Tracing Reveals Shared Origin of Conventional and Plasmacytoid Dendritic Cells
Immunity, 2022Nicholas M. Adams +2 more
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Innate IL-13 Licenses Dermal Type 2 Dendritic Cells for Efficient T Helper 2 Cell Responses
Nature Reviews Immunology, 2021Raphaël Mattiuz, Miriam Merad
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Genetic Models of Human and Mouse Dendritic Cell Development and Function
Nature Reviews Immunology, 2021Charles-Antoine Dutertre +2 more
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