Results 251 to 260 of about 6,856,628 (321)

Freestanding Bamboo‐Like Nitrogen‐Doped Carbon Nanofibers/PANI Dual‐Conductive Cathodes via Interfacial Engineering for High‐Performance Lithium–Sulfur Batteries

open access: yesAdvanced Science, EarlyView.
Bamboo‐like nitrogen‐doped carbon fibers (BNCFs) were synthesized via a vapor‐liquid‐solid catalytic growth method and further integrated with polyaniline to fabricate a freestanding BNCFs/S/PANI cathode. The PANI coating and BNCFs framework synergistically establish an interconnected conductive network with abundant nitrogen‐active sites, thereby ...
Jie Yang   +5 more
wiley   +1 more source

Autoantigen mRNA‐LNP Vaccination Drives Therapeutic Efficacy in Preclinical Models for Autoimmunity

open access: yesAdvanced Science, EarlyView.
Systemic and intramuscular delivery of autoantigen mRNA via lipid nanoparticles reprograms antigen‐presenting cells toward a mature, homeostatic state, driving antigen‐specific T cell exhaustion and providing therapeutic efficacy across autoimmune disease models.
Paulien Baeten   +30 more
wiley   +1 more source

A Pancreatitis‐Inspired Trypsinogen Nanoplatform Reprograms Tumor‐Associated Macrophages via NF‐κB for Pancreatic Cancer Immunotherapy

open access: yesAdvanced Science, EarlyView.
Trypsinogen‐loaded nanoparticles reprogram TAMs via NF‐κB/NLRP3, driving M2→M1 conversion and potent phagocytosis to unleash antitumor immunity. ABSTRACT Although reprogramming tumor‐associated macrophages (TAMs) represents a promising therapeutic strategy, approaches that are both precise and safe remain scarce.
Lei Cao   +7 more
wiley   +1 more source

Penfluridol Triggers GSDME‐Mediated Immunogenic Pyroptosis to Potentiate Antitumor Immunotherapy

open access: yesAdvanced Science, EarlyView.
A high‐throughput screen of FDA‐approved antipsychotics identifies penfluridol as a potent pyroptosis inducer acting via direct TTI1 inhibition. This triggers TNFA‐NFKB signaling and caspase‐8/‐3‐dependent GSDME cleavage. The compound stimulates antitumor immunity alone and synergizes with anti‐PD‐1 therapy, while low TTI1 expression emerges as a ...
Linfeng Li   +11 more
wiley   +1 more source

Discovering Early‐Stage Gas Generation Kinetics Enables Thermal Runaway Early Warning in Lithium‐Ion Batteries

open access: yesAdvanced Science, EarlyView.
Operando gas diagnostics reveal a previously unrecognized chemical activation (CA) stage during thermal runaway in lithium‐ion batteries. A physics‐informed gas generation kinetics network (GGKNet) is developed to reconstruct reaction pathways and physical models automatically.
Jiabo Zhang   +6 more
wiley   +1 more source

Enhancing All‐Solid‐State Batteries Performance Through Thickness Control and Surface Passivation of Thermally Evaporated Lithium Metal Anodes

open access: yesAdvanced Science, EarlyView.
This study demonstrates that thermally evaporated lithium anodes combined with LiF passivation provide a high‐performance thin anode design for next‐generation ASSBs. This approach increases the critical current density from 1.6 to 2.6 mA cm−2, enabling full cells to achieve over 500 and 300 cycles at 1.5 and 3 mA cm−2, respectively, outperforming even
Jinsong Zhang   +4 more
wiley   +1 more source

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