Results 241 to 250 of about 6,856,628 (321)

Targeting the ATX‐LPA Axis Overcomes TKI Resistance and Immunosuppression in Renal Cell Carcinoma via Dual Inhibition of AKT/mTOR and TBK1/IRF3 Pathways

Advanced Science, EarlyView.
ABSTRACT Background Therapeutic resistance limits durable survival in advanced/metastatic renal cell carcinoma (RCC) treated with first‐line tyrosine kinase inhibitor (TKI) plus immune checkpoint inhibitor (ICI). We sought to define key resistance drivers and actionable targets.
Jinchen Luo, Hansen Lin, Haoqian Feng, Lei Tan, Xi Liu, Yong Huang, Junjie Cen, Jiajie Chen, Xinwei Zhou, Mingjie Lin, Wuyuan Liao, Zheyu Ai, Minyu Chen, Yinghan Wang, Wei Chen, Junhang Luo, Yanping Liang   +16 more
wiley   +1 more source

Plasmodium yoelii infection induces lung injury by modulating type 2 conventional dendritic cells autophagy via the STAT3-IRF4 signaling. [PDF]

Cell Death Dis
Hong C, Deng G, Jiang Z, Lu Y, Wu Q, Huang C, Tang J, Zhou H, Liu Q, Luo X, Zhao Y, Qi Y, Li Q, Ma X, Yang Q.   +14 more
europepmc   +1 more source

Human invariant natural killer T cells promote tolerance by preferential apoptosis induction of conventional dendritic cells. [PDF]

Haematologica, 2022
Schmid H, Ribeiro EM, Secker KA, Duerr-Stoerzer S, Keppeler H, Dong R, Munz T, Schulze-Osthoff K, Hailfinger S, Schneidawind C, Schneidawind D.   +10 more
europepmc   +1 more source

High‐Performance Transparent Solid Polymer Electrolyte Based on Copolymer of Deep Eutectic Electrolyte and Methyl Methacrylate for Electrochemical Devices

Advanced Science, EarlyView.
A copolymerization strategy using a polymerizable deep eutectic electrolyte with MMA forms efficient ion‐transport pathways while maintaining excellent transparency. The solid polymer electrolyte simultaneously achieves 17.8 MPa mechanical strength and 1.43 mS cm−1 ionic conductivity, enhancing long‐term cycling stability in Li|LFP batteries and ...
Tingting Chen, Sijia Han, Likun Wang, Sainan Ma, Liping Zhang, Yong Liu, Gaorong Han   +6 more
wiley   +1 more source

Ontogenetic Diversification of Type 2 Conventional Dendritic Cells in the Bone Marrow: A Central Logic for Peripheral Immunity. [PDF]

Immunol Rev
Baber RW, Magalhães-Patrício MÂ, Pires MV, Correia V, Lozano-Gil JM, Guimarães JC, Brown CC, Dalod M, Minutti CM.   +8 more
europepmc   +1 more source

Congenital Deficiency of Conventional Dendritic Cells Promotes the Development of Atopic Dermatitis-Like Inflammation. [PDF]

Front Immunol, 2021
Nishikawa Y, Fukaya T, Fukui T, Uto T, Takagi H, Nasu J, Miyanaga N, Riethmacher D, Choijookhuu N, Hishikawa Y, Amano M, Sato K.   +11 more
europepmc   +1 more source

IL-23 (Interleukin-23)–Producing Conventional Dendritic Cells Control the Detrimental IL-17 (Interleukin-17) Response in Stroke

Stroke, 2018
M. Gelderblom, Mattia Gallizioli, P. Ludewig, V. Thom, Priyadharshini Arunachalam, B. Rissiek, C. Bernreuther, M. Glatzel, T. Korn, T. Arumugam, J. Sedlacik, C. Gerloff, E. Tolosa, A. Planas, T. Magnus   +14 more
semanticscholar   +1 more source

NIR‐II Light‐Triggered Electron Flow Initiates Cuproptosis‐Centered Thermoelectric‐Immunotherapy for Breast Cancer

Advanced Science, EarlyView.
A NIR‐II light‐activatable thermoelectric nanoreactor converts surface‐bound Cu2+ into bioactive Cu+ via directed electron flow. This spatiotemporally controlled reduction triggers potent cuproptosis and immunogenic cell death, eradicating primary tumors and, together with aPD‐1 therapy, suppressing metastases while establishing durable immune memory ...
Boyu Yuan, Qin Fan, Shushu Chu, Shining Yang, Yuechao Yang, Chenxi Zhang, Jinqiao Zhang, Xinran Qu, Yiju Wei, Xin Wang, Ziliang Dong   +10 more
wiley   +1 more source

Human type 1 conventional dendritic cells contribute to skin transplant rejection. [PDF]

Am J Transplant
Borges TJ, Lee CAA, Mucciarone K, Lima K, Lape IT, Lima-Filho M, Ayoama B, Kollar B, Gassen RB, Bonorino C, Talbot SG, Pomahac B, Lian CG, Murphy GF, Riella LV.   +14 more
europepmc   +1 more source

Plasmacytoid and conventional dendritic cells cooperate in crosspriming AAV capsid-specific CD8+ T cells.

Blood, 2017
G. Rogers, Jamie L. Shirley, I. Zolotukhin, Sandeep R. P. Kumar, A. Sherman, G. Perrin, Brad E. Hoffman, A. Srivastava, E. Basner-Tschakarjan, M. Wallet, C. Terhorst, Moanaro Biswas, R. Herzog   +12 more
semanticscholar   +1 more source