Results 21 to 30 of about 15,951 (206)
Journal of Applied Animal Nutrition, 2020 Coenzyme Q10 (CoQ10) is an essential component of the mitochondrial electron transport chain (ETC). Decreased skeletal muscle CoQ10 content may result in decreased ETC activity and energy production.
M.F. Rooney +6 more
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, 2020 The decline of the immune system associated to aging is becoming a global issue nowadays due to the increase of lifespan. Immunosenescence is the deteriorated adaptative capacity of the immune system leading to increase in morbidity and mortality in elderly population. Aging has been related to a progressive affectation of mitochondria such as increase
Hernández-Camacho, Juan Diego +2 more
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The potential therapeutic effects of coenzyme Q10 on the sciatic nerve regeneration following short- and long-term injury [PDF]
Exploration of Neuroprotective TherapyAim: This study aims to investigate the effects of administering coenzyme Q10 (CoQ10) after both short-term and long-term sciatic nerve damage. Methods: Six groups of adult male Wistar albino rats were used. Sciatic nerve injury was performed on the rats
Ahmed Omer Mead +2 more
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CoQ10 Improves Myocardial Damage in Doxorubicin-Induced Heart Failure in C57BL/6 Mice
Frontiers in Bioscience-Landmark, 2022 Background: Cardiovascular disease is associated with high morbidity and mortality. Doxorubicin (DOX) is an effective adjunct to cancer chemotherapy but leads to cardiovascular-related side effects.
Zuowei Pei +6 more
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Clinical syndromes associated with Coenzyme Q10 deficiency. [PDF]
, 2018 Primary Coenzyme Q deficiencies represent a group of rare conditions caused by mutations in one of the genes required in its biosynthetic pathway at the enzymatic or regulatory level.
Alc\ue1zar-Fabra, Maria +2 more
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Primary Coenzyme Q10 Deficiency: An Update
Antioxidants, 2023 Coenzyme Q10 (CoQ10) has a number of vital functions in all cells, both mitochondrial and extra-mitochondrial. In addition to its key role in mitochondrial oxidative phosphorylation, CoQ10 serves as a lipid soluble antioxidant and plays an important role
David Mantle +3 more
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A novel COQ7 mutation causing primarily neuromuscular pathology and its treatment options
Molecular Genetics and Metabolism Reports, 2022 Coenzyme Q10 (CoQ10) is necessary as electron transporter in mitochondrial respiration and other cellular functions. CoQ10 is synthesized by all cells and defects in the synthesis pathway result in primary CoQ10 deficiency that frequently leads to severe
Ying Wang, Evren Gumus, Siegfried Hekimi
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Coenzyme Q10 dose-escalation study in hemodialysis patients: safety, tolerability, and effect on oxidative stress. [PDF]
, 2015 BackgroundCoenzyme Q10 (CoQ10) supplementation improves mitochondrial coupling of respiration to oxidative phosphorylation, decreases superoxide production in endothelial cells, and may improve functional cardiac capacity in patients with congestive ...
Ahmad, Suhail +10 more
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Mitochondrial Dysfunction in Aging and Diseases of Aging. [PDF]
, 2019 Mitochondria have been increasingly recognized as the important players in the aging process [...]
Haas, Richard H
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CoQ10 Deficiency: The Lysosomal Paradigm [PDF]
, 2022 Coenzyme Q10 (CoQ10) deficiency currently represents the only treatable disorder of the mitochondrial electron transport chain (METC). Generally, in patients with CoQ10 deficiency there is some form of neurological impairment typically presenting as either ataxia and/or seizures.
openaire +1 more source