Results 11 to 20 of about 15,919 (216)
Biology, 2019 The aging process includes impairment in mitochondrial function, a reduction in anti-oxidant activity, and an increase in oxidative stress, marked by an increase in reactive oxygen species (ROS) production.
Barcelos, Isabella Peixoto de +1 more
core +7 more sources
Liposome/gold hybrid nanoparticle encoded with CoQ10 (LGNP-CoQ10) suppressed rheumatoid arthritis via STAT3/Th17 targeting. [PDF]
PLoS ONE, 2020 Coenzyme Q10 (CoQ10), also known as ubiquinone, is a fat-soluble antioxidant. Although CoQ10 has not been approved as medication by the Food and Drug Administration, it is widely used in dietary supplements.
Jooyeon Jhun +8 more
doaj +4 more sources
CoQ10'nin solunum zincirindeki etkisi
Sakarya Tıp Dergisi, 2013 CoQ10 seviyesinin yaşlanmayla birlikte azaldığı bilinmektedir. Kalp sağlığı için CoQ10'nin seviyesi önemlidir. CoQ10 mitokondrial solunum zincirinde bir elektron taşıyıcısı olarak, bunu yanı sıra önemli bir hücre içi antioksidan olarak görev yapar. CoQ10
Başar Altınterim
doaj +4 more sources
BPM31510 Increases the CoQ Pool in Chemically Induced CoQ-Deficient Cells, CoQ-Deficient Patient Fibroblasts, and in Metabolically Active Murine Tissues. [PDF]
FASEB JGraphical abstract illustrating the in vitro and in vivo experimental workflow used to compare BPM31510, a nanoliposomal formulation of oxidized CoQ10, with conventional CoQ10. Chemically induced CoQ‐deficient SH‐SY5Y cells, CoQ‐deficient patient fibroblasts, and C57BL/6J mice receiving oral CoQ10 or intraperitoneal BPM31510 were subjected to plasma ...
Aristizabal-Henao JJ +18 more
europepmc +2 more sources
CoQ10 deficiency diseases in adults [PDF]
Mitochondrion, 2007 Deficiency of Coenzyme Q10 (CoQ10) in muscle has been associated with a spectrum of diseases including infantile-onset multi-systemic diseases, encephalomyopathies with recurrent myobinuria, cerebellar ataxia, and pure myopathy. CoQ10 deficiency predominantly affects children, but patients have presented with adult-onset cerebellar ataxia or myopathy ...
Catarina M, Quinzii +2 more
openaire +2 more sources
Shipin gongye ke-ji, 2022 Coenzyme Q10 nanoemulsion (CoQ10-NE) was improved and made utilizing Pinus koraiensis nuts oil as the oil phase, soybean lecithin as the surfactant, and ethanol as the cosurfactant in this study. The effects of different factors on the mean particle size
Zhongjuan WANG +5 more
doaj +1 more source
PLoS ONE, 2022 BackgroundOsteoarthritis (OA) is the most common degenerative joint disease and is characterized by breakdown of joint cartilage. Coenzyme Q10 (CoQ10) exerts diverse biological effects on bone and cartilage; observational studies have suggested that ...
Hyun Sik Na +9 more
doaj +1 more source
Therapeutic potential of co-enzyme Q10 in retinal diseases [PDF]
, 2017 Coenzyme Q10 (CoQ10) plays a critical role in mitochondrial oxidative phosphorylation by serving as an electron carrier in the respiratory electron transport chain.
Marcheggiani, Fabio +6 more
core +1 more source
Bioavailability of Reduced Coenzyme Q10 (Ubiquinol-10) in Burn Patients
Metabolites, 2022 Mitochondrial dysfunction has been implicated in the pathogenesis of inflammation and multi-organ dysfunction in major trauma, including burn injury.
Naohide Kuriyama +7 more
doaj +1 more source
Coenzyme Q10 dose-escalation study in hemodialysis patients: safety, tolerability, and effect on oxidative stress. [PDF]
, 2015 BackgroundCoenzyme Q10 (CoQ10) supplementation improves mitochondrial coupling of respiration to oxidative phosphorylation, decreases superoxide production in endothelial cells, and may improve functional cardiac capacity in patients with congestive ...
Ahmad, Suhail +10 more
core +2 more sources