Results 41 to 50 of about 9,756 (188)

Coenzyme Q10 defects may be associated with a deficiency of Q10-independent mitochondrial respiratory chain complexes

Biological Research
BACKGROUND: Coenzyme Q10 (CoQ10 or ubiquinone) deficiency can be due either to mutations in genes involved in CoQ10 biosynthesis pathway, or to mutations in genes unrelated to CoQ10 biosynthesis.
Konstantina Fragaki, Annabelle Chaussenot, Jean-François Benoist, Samira Ait-El-Mkadem, Sylvie Bannwarth, Cécile Rouzier, Charlotte Cochaud, Véronique Paquis-Flucklinger   +7 more
doaj   +1 more source

Protective Effect of Coenzyme Q10 on Methamphetamine-Induced Apoptosis in Adult Male Rats

Novelty in Biomedicine, 2017
Background: The negative consequence of methamphetamine abuse is due to neuropathologic changes in the brain, which reduces dopaminergic neurons and result in damage to different brain areas.
Fatemeh Gholipour, Jamal Shams, Alireza Zahiroddin   +2 more
doaj   +1 more source

Chaetocin Induces Ferroptosis in Cisplatin‐Resistant Ovarian Cancer Cells Through Neddylation‐Mediated TFRC Upregulation

Phytotherapy Research, EarlyView.
Chaetocin induces ferroptosis in cisplatin‐resistant ovarian cancer cells through neddylation‐mediated TFRC upregulation. ABSTRACT Ovarian cancer (OV) is a highly lethal gynecological tumor, often developing platinum chemotherapy resistance and treatment failure.
Hanfei Xie, Wumin Dai, Lu Sun, Wangang Gong, Tao Zhu, Yingli Zhang   +5 more
wiley   +1 more source

Efficacy and safety of pharmacological interventions for the treatment of cocaine use disorder: A systematic review and network meta‐analysis

Addiction, EarlyView.
Abstract Background and aims Cocaine use disorder (CUD) is an increasingly widespread concern worldwide. Various pharmacological treatments have been investigated for CUD, but their efficacy remains unclear, and none have been licensed for treatment.
Craig Paterson, Thomas Parkhouse, Chloe Burke, Monika Halicka, Jennifer C. Palmer, Hend Gabr, Rebecca Wilson, Katie E. Webster, Francesca Spiga, Sarah Dawson, Deborah M. Caldwell, Jennifer Scott, Julian P. T. Higgins, Jelena Savović   +13 more
wiley   +1 more source

Serum Levels of Coenzyme Q10 in Patients with Multiple System Atrophy. [PDF]

PLoS ONE, 2016
The COQ2 gene encodes an essential enzyme for biogenesis, coenzyme Q10 (CoQ10). Recessive mutations in this gene have recently been identified in families with multiple system atrophy (MSA).
Takashi Kasai, Takahiko Tokuda, Takuma Ohmichi, Ryotaro Ishii, Harutsugu Tatebe, Masanori Nakagawa, Toshiki Mizuno   +6 more
doaj   +1 more source

Impact of Coenzyme Q10 Supplementation on Skeletal Muscle Respiration, Antioxidants, and the Muscle Proteome in Thoroughbred Horses

Antioxidants, 2023
Coenzyme Q10 (CoQ10) is an essential component of the mitochondrial electron transfer system and a potent antioxidant. The impact of CoQ10 supplementation on mitochondrial capacities and the muscle proteome is largely unknown.
Marisa L. Henry, Lauren T. Wesolowski, Joe D. Pagan, Jessica L. Simons, Stephanie J. Valberg, Sarah H. White-Springer   +5 more
doaj   +1 more source

Fluoride‐Free Mouthwashes Available Over‐The‐Counter in the US‐An Overview

International Journal of Dental Hygiene, EarlyView.
ABSTRACT Purpose Fluoride‐free mouthwashes (FFM) are commonly used by patients for a variety of cosmetic and/or therapeutic reasons. The purpose of this study was to investigate the composition and purposes of FFM available over‐the‐counter in the US.
Astrid C. Valdivia‐Tapia, Jaime A. Cury, Antonio P. Ricomini‐Filho, Frank Lippert   +3 more
wiley   +1 more source

Prophylactic Effectiveness of Coenzyme Q10 for Migraine in Adults: A Systematic Review and Meta-Analysis of Double-Blinded Randomized Clinical Trials

Traditional and Integrative Medicine
We aimed to evaluate the influence of coenzyme Q10 alone (CoQ10) or in association with other nutraceuticals (CoQ10+) on the frequency, severity, duration of migraine attacks, and quality of life. We conducted a meta-analysis and a network meta-analysis
Emna Ellouz, Imen Ketata
doaj   +1 more source

Revisiting Inherited Metabolic Diseases (IMDs) Through the Lens of Selective Autophagy

Journal of Inherited Metabolic Disease, Volume 49, Issue 6, November 2026.
ABSTRACT Selective autophagy is increasingly recognized as a fundamental quality‐control mechanism that complements bulk autophagy by enabling the targeted degradation of specific intracellular cargos, including mitochondria, endoplasmic reticulum (ER), lipid droplets, glycogen, peroxisomes, ferritin, ribosomes, and protein aggregates.
Marianna Maddaluno, Laura Cinque, Viviana Cetrangolo, Chiara De Leonibus   +3 more
wiley   +1 more source

CoenzymeQ10 and Ischemic Preconditioning Potentially Prevent Tourniquet-Induced Ischemia/Reperfusion in Knee Arthroplasty, but Combined Pretreatment Possibly Neutralizes Their Beneficial Effects

Antioxidants, 2022
Tourniquet (TQ) use during total knee arthroplasty (TKA) induces ischemia/reperfusion (I/R) injury, resulting in mitochondrial dysfunction. This study aims to determine the effects of coenzyme Q10 (CoQ10) and ischemic preconditioning (IPC), either alone ...
Prangmalee Leurcharusmee, Passakorn Sawaddiruk, Yodying Punjasawadwong, Nantawit Sugundhavesa, Kasisin Klunklin, Siam Tongprasert, Patraporn Sitilertpisan, Thidarat Jaiwongkam, Nattayaporn Apaijai, Nipon Chattipakorn, Siriporn C. Chattipakorn   +10 more
doaj   +1 more source