Solubility of mesalazine in pseudo-binary mixtures of choline chloride/ethylene glycol deep eutectic solvent and water at 293.15 K to 313.15 K [PDF]
Mesalazine (5-ASA) is a medication utilized to treat inflammatory bowel diseases involving ulcerative colitis and Crohn’s disease. Mesalazine has fewer side effects but the low solubility and bioavailability of it is responsible for its delayed onset of ...
Elina Armani +5 more
doaj +3 more sources
Sonication-assisted nonpolar-antisolvent approach to produce cellulose suspensions, disaggregated by a nonpolar-antisolvent with orthogonal Kamlet-Taft acidity/basicity: Roles of net-basicity and cosolvency [PDF]
This work reports a simple sonication-assisted approach to produce diluted (0.5 mg/mL) suspensions of cellulose in the non-functionalizing nonpolar-antisolvent tetrahydrofuran (THF), which has a purely basic character (null Kamlet-Taft acidity parameter,
Sergio E. Domínguez +5 more
doaj +3 more sources
Review of the cosolvency models for predicting solubility of drugs in water-cosolvent mixtures
The cosolvency models presented from 1960 to 2007 were reviewed and their accuracies for correlating and/or predicting the solubility of drugs in water-cosolvent mixtures were discussed.
Abolghasem Jouyban
doaj +4 more sources
Thermodynamic Study of the Solubility of Triclocarban in Polyethylene Glycol 200 + Water Cosolvent Mixtures at Different Temperatures [PDF]
Background: Solubility is a fundamental physicochemical property in pharmaceutical, chemical and environmental industrial processes. Regarding Triclocarban (TCC), a broad-spectrum antimicrobial, solubility is particularly challenging due to its low ...
Vanesa Puentes-Lozada +7 more
doaj +2 more sources
Measurement and correlation of solubility data for deferiprone in propylene glycol and 2-propanol at different temperatures [PDF]
This investigation dealt with the thermodynamic properties, saturated solubility values, and solvation behavior of deferiprone as an oral iron chelator agent in non-aqueous mixtures of propylene glycol and 2-propanol using experimental measurements and ...
Homa Rezaei +3 more
doaj +2 more sources
Thermodynamic Assessment of Triclocarban Dissolution Process in N-Methyl-2-pyrrolidone + Water Cosolvent Mixtures [PDF]
Solubility is one of the most important physicochemical properties due to its involvement in physiological (bioavailability), industrial (design) and environmental (biotoxicity) processes, and in this regard, cosolvency is one of the best strategies to ...
Diego Ivan Caviedes-Rubio +3 more
doaj +2 more sources
Application of cosolvency and cocrystallization approach to enhance acyclovir solubility [PDF]
Acyclovir (ACY) is a commonly used antiviral drug with limited aqueous solubility and poor permeability. It is administered via oral and intravenous routes.
Elham Azad Khiabani +2 more
doaj +2 more sources
Nonadditive CO<sub>2</sub> Uptake of Type II Porous Liquids Based on Imine Cages. [PDF]
Type II porous liquids based on porous imine cages (CC13/CC19) show non‐additive CO2 uptake, surpassing ideal volume additivity predictions. Experiments and simulations reveal enhanced gas absorption, with CO2 partitioning into cage pores and solvent.
Lu L +5 more
europepmc +2 more sources
Solubility and thermodynamic study of deferiprone in propylene glycol and ethanol mixture [PDF]
This work aims to obtain the solubility, density and thermodynamic parameters of deferiprone in propylene glycol and ethanol. For this purpose, a shake-flask technique was applied for solid–liquid equilibration and the spectrophotometry method was ...
Samira Radmand +4 more
doaj +2 more sources
Thermodynamic solubility of piroxicam in propylene glycol + water mixtures at 298.2-323.2 K: Data report and modeling [PDF]
The solubility of piroxicam (66 data points) in binary mixtures of propylene glycol (PG) + water at six different temperatures which ranged from 298.2 K to 323.2 K were reported.
Soltanpour Shahla, Bastami Zahra
doaj +2 more sources

