Results 11 to 20 of about 44,983 (183)
CpG island mapping by epigenome prediction. [PDF]
PLoS Computational Biology, 2007 CpG islands were originally identified by epigenetic and functional properties, namely, absence of DNA methylation and frequent promoter association. However, this concept was quickly replaced by simple DNA sequence criteria, which allowed for genome ...
Christoph Bock +3 more
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Comparative analysis of CpG islands among HBV genotypes. [PDF]
PLoS ONE, 2013 DNA methylation is being increasingly recognized to play a role in regulation of hepatitis B virus (HBV) gene expression. The aim of this study was to compare the CpG island distribution among different HBV genotypes.
Yongmei Zhang +11 more
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Particle swarm optimization with reinforcement learning for the prediction of CpG islands in the human genome. [PDF]
PLoS ONE, 2011 BACKGROUND: Regions with abundant GC nucleotides, a high CpG number, and a length greater than 200 bp in a genome are often referred to as CpG islands. These islands are usually located in the 5' end of genes.
Li-Yeh Chuang +3 more
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CpG islands undermethylation in human genomic regions under selective pressure. [PDF]
PLoS ONE, 2011 DNA methylation at CpG islands (CGIs) is one of the most intensively studied epigenetic mechanisms. It is fundamental for cellular differentiation and control of transcriptional potential.
Sergio Cocozza +3 more
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Intergenic, gene terminal, and intragenic CpG islands in the human genome
BMC Genomics, 2010 Background Recently, it has been discovered that the human genome contains many transcription start sites for non-coding RNA. Regulatory regions related to transcription of this non-coding RNAs are poorly studied.
Kulakovskiy Ivan V +7 more
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Genome Research, 1997 We describe an analysis of the CpG islands (CGIs) of the pig. We have used both database survey and a porcine genomic library that is enriched for CGIs. Approximately half of 41 pig genomic database sequences had CGIs with an average G + C content of 65.3%, an average CpG observed/expected frequency of 0.85, and an average size of 978 bp.
McQueen, H A +4 more
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PLoS ONE, 2007 BackgroundMajority of CpG dinucleotides in mammalian genomes tend to undergo DNA methylation, but most CpG islands are resistant to such epigenetic modification. Understanding about mechanisms that may lead to the methylation resistance of CpG islands is
Shicai Fan +3 more
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Ornithine decarboxylase antizyme induces hypomethylation of genome DNA and histone H3 lysine 9 dimethylation (H3K9me2) in human oral cancer cell line. [PDF]
PLoS ONE, 2010 Methylation of CpG islands of genome DNA and lysine residues of histone H3 and H4 tails regulates gene transcription. Inhibition of polyamine synthesis by ornithine decarboxylase antizyme-1 (OAZ) in human oral cancer cell line resulted in accumulation of
Daisuke Yamamoto +7 more
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Prediction of CpG-island function: CpG clustering vs. sliding-window methods
BMC Genomics, 2010 Background Unmethylated stretches of CpG dinucleotides (CpG islands) are an outstanding property of mammal genomes. Conventionally, these regions are detected by sliding window approaches using %G + C, CpG observed/expected ratio and length thresholds as
Luque-Escamilla Pedro L +5 more
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Evolution of CpG-islands by means of tandem duplications
Вавиловский журнал генетики и селекции, 2017 CG-rich islands (CpG-islands, or CGI) are important functional elements in a genome of vertebrates. In particular, they: a) initiate transcription as promoters in most (> 50 %) genes of vertebrates, in some cases bi-directional, due to self-complement
V. N. Babenko +4 more
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