Results 11 to 20 of about 71,046 (242)
Comparative analysis of CpG islands among HBV genotypes. [PDF]
PLoS ONE, 2013 DNA methylation is being increasingly recognized to play a role in regulation of hepatitis B virus (HBV) gene expression. The aim of this study was to compare the CpG island distribution among different HBV genotypes.
Yongmei Zhang +11 more
doaj +1 more source
Particle swarm optimization with reinforcement learning for the prediction of CpG islands in the human genome. [PDF]
PLoS ONE, 2011 BACKGROUND: Regions with abundant GC nucleotides, a high CpG number, and a length greater than 200 bp in a genome are often referred to as CpG islands. These islands are usually located in the 5' end of genes.
Li-Yeh Chuang +3 more
doaj +1 more source
CpG islands undermethylation in human genomic regions under selective pressure. [PDF]
PLoS ONE, 2011 DNA methylation at CpG islands (CGIs) is one of the most intensively studied epigenetic mechanisms. It is fundamental for cellular differentiation and control of transcriptional potential.
Sergio Cocozza +3 more
doaj +1 more source
A Hybrid Approach for CpG Island Detection in the Human Genome. [PDF]
PLoS ONE, 2016 BACKGROUND:CpG islands have been demonstrated to influence local chromatin structures and simplify the regulation of gene activity. However, the accurate and rapid determination of CpG islands for whole DNA sequences remains experimentally and ...
Cheng-Hong Yang +3 more
doaj +1 more source
Intergenic, gene terminal, and intragenic CpG islands in the human genome
BMC Genomics, 2010 Background Recently, it has been discovered that the human genome contains many transcription start sites for non-coding RNA. Regulatory regions related to transcription of this non-coding RNAs are poorly studied.
Kulakovskiy Ivan V +7 more
doaj +1 more source
Histone methylation marks play important roles in predicting the methylation status of CpG islands [PDF]
, 2008 The methylation status of CpG islands is highly correlated with gene expression. Current methods for computational prediction of DNA methylation only utilize DNA sequence features.
Fan, S., Zhang, M. Q., Zhang, X.
core +1 more source
DNA methylation and chromatin structure: The puzzling CpG islands [PDF]
, 2005 DNA methylation is the epigenetic modification,which introduces 5mC as fifth base onto DNA. As for the distribution of 5rnCs, it is well known that they distribute themselves in a non-random fashion in genomic DNA so that methylation pattern is ...
CAIAFA, Paola, ZAMPIERI, Michele
core +1 more source
Within-pair differences of DNA methylation levels between monozygotic twins are different between male and female pairs [PDF]
, 2016 BACKGROUND: DNA methylation levels will be important for detection of epigenetic effects. However, there are few reports showing sex-related differences in the sensitivity to DNA methylation.
Chika Honda +14 more
core +1 more source
Genome Research, 1997 We describe an analysis of the CpG islands (CGIs) of the pig. We have used both database survey and a porcine genomic library that is enriched for CGIs. Approximately half of 41 pig genomic database sequences had CGIs with an average G + C content of 65.3%, an average CpG observed/expected frequency of 0.85, and an average size of 978 bp.
McQueen, H A +4 more
openaire +3 more sources