Results 61 to 70 of about 44,983 (183)

Analysis of CpG methylation sites and CGI among human papillomavirus DNA genomes

BMC Genomics, 2011
Background The Human Papillomavirus (HPV) genome is divided into early and late coding sequences, including 8 open reading frames (ORFs) and a regulatory region (LCR).
Galván Silvia C, Martínez-Salazar Martha, Galván Víctor M, Méndez Rocío, Díaz-Contreras Gibran T, Alvarado-Hermida Moisés, Alcántara-Silva Rogelio, García-Carrancá Alejandro   +7 more
doaj   +1 more source

Cosmid walking and chromosome jumping in the region of PKD1 reveal a locus duplication and three CpG islands [PDF]

, 1990
Gerald A.J. Gillespie, Gregory G. Germino, Stefan Somio, Debra Weinstat‐Saslow, Martijn H. Breuning, Stephen T. Reeders   +5 more
openalex   +1 more source

CpG islands or CpG clusters: how to identify functional GC-rich regions in a genome?

BMC Bioinformatics, 2009
Background CpG islands (CGIs), clusters of CpG dinucleotides in GC-rich regions, are often located in the 5' end of genes and considered gene markers. Hackenberg et al.
Han Leng, Zhao Zhongming
doaj   +1 more source

CpG island methylator phenotype and its association with malignancy in sporadic duodenal adenomas [PDF]

, 2014
Lifeng Sun, Angela A. Guzzetta, Tao Fu, Jinming Chen, Jana Jeschke, Ruby Kwak, Rajita Vatapalli, Stephen B. Baylin, Christine A. Iacobuzio–Donahue, Christopher L. Wolfgang, Nita Ahuja   +10 more
openalex   +1 more source

Supplementary table 4 from <i>WRN</i> Promoter CpG Island Hypermethylation Does Not Predict More Favorable Outcomes for Patients with Metastatic Colorectal Cancer Treated with Irinotecan-Based Therapy

, 2023
Linda J.W. Bosch, Yanxin Luo, Victoria Valinluck Lao, Pétur Snæbjörnsson, Geert Trooskens, Ilse Vlassenbroeck, Sandra Mongera, Weiliang Tang, Piri Welcsh, James G. Herman, Miriam Koopman, Irıs D. Nagtegaal, Cornelis J.A. Punt, Wim Van Criekinge, Gerrit A. Meijer, Raymond J. Monnat, Beatriz Carvalho, William M. Grady   +17 more
openalex   +1 more source

SARS-CoV-2 hot-spot mutations are significantly enriched within inverted repeats and CpG island loci [PDF]

, 2020
Pratik Goswami, Martin Bartas, Matej Lexa, Natália Bohálová, Adriana Volná, Jiří Červeň, Veronika Červeňová, Petr Pečínka, Vladimı́r Špunda, Miroslav Fojta, Václav Brázda   +10 more
openalex   +1 more source

DNA methylation correlates of chronological age in diverse human tissue types

Epigenetics & Chromatin
Background While the association of chronological age with DNA methylation (DNAm) in whole blood has been extensively studied, the tissue-specificity of age-related DNAm changes remains an active area of research. Studies investigating the association of
Niyati Jain, James L. Li, Lin Tong, Farzana Jasmine, Muhammad G. Kibriya, Kathryn Demanelis, Meritxell Oliva, Lin S. Chen, Brandon L. Pierce   +8 more
doaj   +1 more source

The topography of nullomer-emerging mutations and their relevance to human disease

Computational and Structural Biotechnology Journal
Nullomers are short DNA sequences (11–18 base pairs) that are absent from a genome; however, they can emerge due to mutations. Here, we characterize all possible putative human nullomer-emerging single base pair mutations, population variants and disease-
Candace S.Y. Chan, Ioannis Mouratidis, Austin Montgomery, Georgios Christos Tsiatsianis, Nikol Chantzi, Martin Hemberg, Nadav Ahituv, Ilias Georgakopoulos-Soares   +7 more
doaj   +1 more source

Intragenic CpG Islands and Their Impact on Gene Regulation. [PDF]

Front Cell Dev Biol, 2022
Cain JA, Montibus B, Oakey RJ.
europepmc   +1 more source

Inflammation-induced up-regulation of TLR2 expression in human endothelial cells is independent of differential methylation in the TLR2 promoter CpG island [PDF]

, 2011
Britta Diesel, Nadège Ripoche, Rebecca T Risch, Sascha Tierling, Jörn Walter, Alexandra K. Kiemer   +5 more
openalex   +1 more source