Results 91 to 100 of about 7,200 (169)

TNF stimulates nuclear export and secretion of IL-15 by acting on CRM1 and ARF6.

PLoS ONE, 2013
Interleukin (IL)-15 is a ubiquitously expressed cytokine that in the basal state is mainly localized intracellularly, including the nucleus. Unexpectedly, tumor necrosis factor-α (TNF) time-dependently induced nuclear export of IL-15Rα and IL15.
Suidong Ouyang, Hung Hsuchou, Abba J Kastin, Weihong Pan   +3 more
doaj   +1 more source

Immunosuppressive Yersinia Effector YopM Binds DEAD Box Helicase DDX3 to Control Ribosomal S6 Kinase in the Nucleus of Host Cells.

PLoS Pathogens, 2016
Yersinia outer protein M (YopM) is a crucial immunosuppressive effector of the plaque agent Yersinia pestis and other pathogenic Yersinia species. YopM enters the nucleus of host cells but neither the mechanisms governing its nucleocytoplasmic shuttling ...
Laura Berneking, Marie Schnapp, Andreas Rumm, Claudia Trasak, Klaus Ruckdeschel, Malik Alawi, Adam Grundhoff, Alexey G Kikhney, Friedrich Koch-Nolte, Friedrich Buck, Markus Perbandt, Christian Betzel, Dmitri I Svergun, Moritz Hentschke, Martin Aepfelbacher   +14 more
doaj   +1 more source

Inter-cellular transport of ran GTPase.

PLoS ONE, 2015
Ran, a member of the Ras-GTPase superfamily, has a well-established role in regulating the transport of macromolecules across the nuclear envelope (NE). Ran has also been implicated in mitosis, cell cycle progression, and NE formation. Over-expression of
Deepak Khuperkar, Mary Helen, Indrasen Magre, Jomon Joseph   +3 more
doaj   +1 more source

The molecular mechanism underlying the differential subcellular distribution of dystrophin Dp71 isoforms. [PDF]

Cell Biosci
Alamillo-Iniesta A, Velez-Aguilera G, Monterrubio-Ledezma F, Ávila-Avilés RD, Suárez-Sánchez R, García-Aguirre I, Lizcano-Meneses S, López-Orona TI, Guevara-Namorado F, Toribio-Valdez A, Hernández-Hernández JM, Arrieta-Cruz I, Magaña JJ, Cisneros B.   +13 more
europepmc   +1 more source

A Unified Model: Chromatin-Bound Multicomponent Condensates. [PDF]

Cancer Res
Lau BK, Haarer EL, Ahn JH, Wang GG.
europepmc   +1 more source

CRM1

Seibutsu Butsuri, 2015
openaire   +2 more sources

Transcription start site heterogeneity controls MDA5 sensing of unspliced HIV-1 RNAs. [PDF]

Proc Natl Acad Sci U S A
Hughes IK, Kharytonchyk S, Ramaswamy S, Jalloh S, Hood JB, He X, Henderson AJ, Akiyama H, Telesnitsky A, Gummuluru S.   +9 more
europepmc   +1 more source

RNA export through the nuclear pore complex: pathways, mechanisms, and imaging strategies. [PDF]

RNA Biol
Fu D, Yu W, Zhang F, Rush C, Tingey M, Yang W.   +5 more
europepmc   +1 more source

CRM1-dependent nuclear export of TRIM28 promotes MAVS K48-linked ubiquitination and suppresses RIG-I-mediated antiviral response. [PDF]

Front Immunol
Xin R, Zou W, Qiu Z, Huang L, Jing X, Huang Q, Zhu Z, Li J, Garigliany MM.   +8 more
europepmc   +1 more source

Escorting mRNAs - the multifunctional and divergent roles of cap-chaperones in post-transcriptional gene expression. [PDF]

J Cell Sci
Embree CM, Borden KLB.
europepmc   +1 more source