Results 31 to 40 of about 714,192 (184)

Discovery and characterization of circulating tumor cell clusters in neuroendocrine tumor patients using nanosubstrate-embedded microchips [PDF]

, 2021
Circulating tumor cell (CTC) clusters are present in cancer patients with severe metastasis, resulting in poor clinical outcomes. However, CTC clusters have not been studied as extensively as single CTCs, and the clinical utility of CTC clusters remains ...
Huang, Yen-Wen, Posadas, Edwin M., Allen-Auerbach, Martin S, Hecht, J Randolph, Hecht, J. Randolph, Heaney, Anthony P., Smalley, Matthew, Hope, Thomas A, Liu, Wenfei, Chou, Shih-Jie, Lee, Yi-Te, Yang, Yingying, Bergsland, Emily K., Huai, Kevin, Teng, Pai-Chi, Weiss, Paul S, Sun, Na, Wang, Jasmine J, Redublo, Peter, Tseng, Hsian-Rong, Allen-Auerbach, Martin S., Zhang, Dongyun, Bergsland, Emily K, Miao, Hui, Wang, Jing, Hope, Thomas A., Posadas, Edwin M, Weiss, Paul S., Liang, Li, Donahue, Timothy, Zhang, Tiffany X, Heaney, Anthony P, Yang, Peng, Zhang, Ryan Y, Zhang, Zhicheng, Wang, Jasmine J., Zhang, Tiffany X., Zhu, Yazhen, Liang, Icy Y, Liu, Hongtao, Zhang, Ceng, Zhang, Ryan Y., Liang, Icy Y., Pei, Renjun, Wenfei Liu, Yingying Yang, Yazhen Zhu, Tiffany X. Zhang, Emily K. Bergsland, Hui Miao, Yi-Te Lee, Hsian-Rong Tseng, Li Liang, Renjun Pei, Martin S. Allen-Auerbach, Peter Redublo, Jasmine J. Wang, Timothy Donahue, Kevin Huai, Jing Wang, Paul S. Weiss, Icy Y. Liang, J. Randolph Hecht, Ryan Y. Zhang, Pai-Chi Teng, Edwin M. Posadas, Anthony P. Heaney, Matthew Smalley, Dongyun Zhang, Na Sun, Peng Yang, Thomas A. Hope, Shih-Jie Chou, Zhicheng Zhang, Hongtao Liu, Ceng Zhang, Yen-Wen Huang   +76 more
core   +1 more source

Prognostic value of circulating tumor cells associated with white blood cells in solid cancer: a systematic review and meta-analysis of 1471 patients with solid tumors

BMC Cancer, 2023
Background The clinical relevance of circulating tumor cell-white blood cell (CTC-WBC) clusters in cancer prognosis is a subject of ongoing debate. This study aims to unravel their contentious predictive value for patient outcomes. Methods We conducted a
Mingguang Ju, Ziming Gao, Gaoxiang Gu, Haibo Huang, Anqi Sun, Chen Zheng, He Li, Yixiao Zhang, Kai Li   +8 more
doaj   +1 more source

Cancer-specific calcium nanoregulator suppressing the generation and circulation of circulating tumor cell clusters for enhanced anti-metastasis combinational chemotherapy

Acta Pharmaceutica Sinica B, 2021
Tumor metastasis is responsible for chemotherapeutic failure and cancer-related death. Moreover, circulating tumor cell (CTC) clusters play a pivotal role in tumor metastasis.
Dan Li, Yingli Wang, Chang Li, Qiu Wang, Bingjun Sun, Haotian Zhang, Zhonggui He, Jin Sun   +7 more
doaj   +1 more source

ADAM19 Promotes EMT-Related Changes and Serves as a Prognostic Marker in Circulating Tumor Cells of Renal Cell Carcinoma. [PDF]

Cancer Sci
ADAM19 is associated with EMT‐related malignant phenotypes and NOTCH/NF‐κB pathway activity in RCC and may serve as a prognostic biomarker in CTCs. ABSTRACT Detection of circulating tumor cells (CTCs), particularly characterization of their epithelial‐mesenchymal transition (EMT) phenotypes, may improve prognostic accuracy for malignancies ...
He M, Li M, Ma Y, Chen Z, Guo L, Wang X, Wang W, Chong T, Wang Z.   +8 more
europepmc   +2 more sources

Functional Characterization of Circulating Tumour Cell (CTC) Clusters in Breast Cancer [PDF]

, 2021
Breast cancer (BC) is the most common malignancy in women and the second leading cause of cancer-related deaths. Most cancer-related deaths are due to metastasis, a process by which tumour cells spread to secondary sites. Circulating tumour cells (CTCs)
Martínez Pena, Inés
core  

Highly Correlated Recurrence Prognosis in Patients with Metastatic Colorectal Cancer by Synergistic Consideration of Circulating Tumor Cells/Microemboli and Tumor Markers CEA/CA19-9

Cells, 2021
Circulation tumor cells (CTCs) play an important role in metastasis and highly correlate with cancer progression; thus, CTCs could be considered as a powerful diagnosis tool.
Hsueh-Yao Chu, Chih-Yung Yang, Ping-Hao Yeh, Chun-Jieh Hsu, Lu-Wei Chang, Wei-Jen Chan, Chien-Ping Lin, You-You Lyu, Wei-Cheng Wu, Chun-Wei Lee, Jen-Kuei Wu, Jeng-Kai Jiang, Fan-Gang Tseng   +12 more
doaj   +1 more source

Agent‐based modelling reveals strategies to reduce the fitness and metastatic potential of circulating tumour cell clusters

Evolutionary Applications, 2020
Metastasis—the ability of cancer cells to disperse throughout the body and establish new tumours at distant locations—is responsible for most cancer‐related deaths.
Marco Campenni, Alexander N. May, Amy Boddy, Valerie Harris, Aurora M. Nedelcu   +4 more
doaj   +1 more source

A model for the dissemination of circulating tumour cell clusters involving platelet recruitment and a plastic switch between cooperative and individual behaviours

BMC Ecology and Evolution, 2023
Background In spite of extensive research, cancer remains a major health problem worldwide. As cancer progresses, cells acquire traits that allow them to disperse and disseminate to distant locations in the body – a process known as metastasis.
Jorian D. Hapeman, Caroline S. Carneiro, Aurora M. Nedelcu   +2 more
doaj   +1 more source

Molecules promoting circulating clusters of cancer cells suggest novel therapeutic targets for treatment of metastatic cancers

Frontiers in Immunology, 2023
Treatment of metastatic disease remains among the most challenging tasks in oncology. One of the early events that predicts a poor prognosis and precedes the development of metastasis is the occurrence of clusters of cancer cells in the blood flow ...
Julian M. Rozenberg, Anton A. Buzdin, Anton A. Buzdin, Anton A. Buzdin, Anton A. Buzdin, Tharaa Mohammad, Olga A. Rakitina, Dmitry A. Didych, Victor V. Pleshkan, Victor V. Pleshkan, Irina V. Alekseenko, Irina V. Alekseenko, Irina V. Alekseenko   +12 more
doaj   +1 more source

Clinical significance and heterogeneity of circulating tumor cells and clusters in breast cancer subtypes [PDF]

PeerJ
The marked heterogeneity of breast cancer results in substantial variations in clinical characteristics, metastatic patterns, and prognosis across molecular subtypes.
LiangYu Hao, Lixiang Zheng
doaj   +2 more sources