Results 21 to 30 of about 714,192 (184)

PDAC CTC/M-FB clusters promoted CTC proliferation and migration.

, 2022
PortalBMC were separated on histopaque gradients and CTC and M-FB cells isolated using aseptic FACS to yield selected populations for defined co-cultures to identify essential populations needed for CTC cluster formation in ex vivo cultures as previously
Joseph Reza (12275293), Juan Pablo Arnoletti (12275290), Otto Phanstiel IV (12275308), Sally A. Litherland (8987780), Na’im Fanaian (8987786), Alberto Monreal (12275296), Deborah A. Altomare (224281), Suzanne Whisner (12275299), Milan Srivastava (12275302), Julia Rivera-Otero (12275305), Gongxin Yu (5649757), Armando Rosales (6736175), Quang Tran (2179564)   +12 more
core   +1 more source

Association of circulating tumor cell-white blood cell clusters with survival outcomes in patients with colorectal cancer after curative intent surgery

BMC Gastroenterology, 2022
Background The analysis of circulating tumor cell-associated white blood cell (CTC-WBC) clusters represented the progress in the liquid biopsy of malignant tumors, however, related research in patients with colorectal cancer is still absent.
Yifan Xu, Qianlong Zhang, Zhou Xu, Qingfeng Xie, Wenfu Ding, Hao Liu, Haijun Deng   +6 more
doaj   +1 more source

Modelling metastasis in zebrafish unveils regulatory interactions of cancer-associated fibroblasts with circulating tumour cells

Frontiers in Cell and Developmental Biology, 2023
The dynamic intercommunication between tumour cells and cells from the microenvironment, such as cancer-associated fibroblast (CAFs), is a key factor driving breast cancer (BC) metastasis.
Pablo Hurtado, Pablo Hurtado, Inés Martínez-Pena, Inés Martínez-Pena, Sabrina Yepes-Rodríguez, Miguel Bascoy-Otero, Carmen Abuín, Cristóbal Fernández-Santiago, Laura Sánchez, Rafael López-López, Rafael López-López, Rafael López-López, Rafael López-López, Roberto Piñeiro, Roberto Piñeiro   +14 more
doaj   +1 more source

Improved Prognostic Stratification Using Circulating Tumor Cell Clusters in Patients with Metastatic Castration-Resistant Prostate Cancer. [PDF]

, 2021
Liquid biopsy-based biomarkers have advantages in monitoring the dynamics of metastatic castration-resistant prostate cancer (mCRPC), a bone-predominant metastatic disease.
Chong, Weelic, Rebbeck, Timothy R, Weelic Chong, Lin, Jianqing, Yang, Hushan, Myers, Ronald E, Jianqing Lin, Wang, Chun, Hushan Yang, Lu-Yao, Grace, Rui Luo, Qiang Wei, Grace Lu-Yao, Chun Wang, Zhenchao Zhang, Bingshan Li, Jian Gu, Gu, Jian, Kelly, William K, Ronald E. Myers, Luo, Rui, Wei, Qiang, Li, Bingshan, Zhang, Zhenchao, Timothy R. Rebbeck, William K. Kelly   +25 more
core   +1 more source

RNA expression of myeloid growth factor signaling ligands and their receptors in uncultured PDAC CTC and M-FB isolated cells and in vivo formed clusters.

, 2022
Uncultured portal blood CTC, M-FB, and in vivo formed CTC+/M-FB+ clusters from PortalBMC of 6 PDAC patients were FACS isolated and collected into RNALater, and then extracted and analyzed for CSF2, CSF1, IL34, CSF1R, and CSF2R RNA expression by real-time
Joseph Reza (12275293), Juan Pablo Arnoletti (12275290), Otto Phanstiel IV (12275308), Sally A. Litherland (8987780), Na’im Fanaian (8987786), Alberto Monreal (12275296), Deborah A. Altomare (224281), Suzanne Whisner (12275299), Milan Srivastava (12275302), Julia Rivera-Otero (12275305), Gongxin Yu (5649757), Armando Rosales (6736175), Quang Tran (2179564)   +12 more
core   +1 more source

Microfluidic techniques for isolation, formation, and characterization of circulating tumor cells and clusters

APL Bioengineering, 2022
Circulating tumor cell (CTC) clusters that are shed from the primary tumor into the bloodstream are associated with a poor prognosis, elevated metastatic potential, higher proliferation rate, and distinct molecular features compared to single CTCs ...
Celine Macaraniag, Qiyue Luan, Jian Zhou, Ian Papautsky   +3 more
doaj   +1 more source

CTC-5: A novel digital pathology approach to characterise circulating tumour cell biodiversity

, 2023
Metastatic progression and tumor evolution complicates the clinical management of cancer patients. Circulating tumor cell (CTC) characterization is a growing discipline that aims to elucidate tumor metastasis and evolution processes.
O'Riain, C., Brooks, R.D., S A O'Toole (14607052), Ffrench, B., Kashdan, E., C D Spillane (14607031), Scholz, D., Leonie Young (7895759), Varešlija, D., Brooks, D.A., Gallagher, M., W Kamran (14607050), O'Toole, S.A., Young, L., Y Huang (5107763), Charmsaz, S., AbuSaadeh, F., C Martin (7772414), J J O'Leary (14607053), Gleeson, N., M Gallagher (13424349), C O'Brien (7805933), Selemidis, S., Sinead Cocchiglia (8484729), Cocchiglia, S., Flavin, R., S Selemidis (9630146), Huang, Y., O'Leary, J.J., B Ffrench (14580358), N Gleeson (14320311), O'Brien, C., C O'Riain (14320245), Kamran, W., E Kashdan (14607028), Damir Vareslija (7895321), Martin, C., D A Brooks (13351527), R Flavin (11499493), R D Brooks (14607045), Spillane, C.D., Sara Charmsaz (7896116), F AbuSaadeh (14607047), D Scholz (14607043), C. Martin, Spillane, C D, D. Scholz, J.J. O'Leary, Scholz, D, Martin, C, W. Kamran, Flavin, R, F. AbuSaadeh, Ffrench, B, Brooks, R D, Selemidis, S, D.A. Brooks, Kamran, W, O'Leary, J J, Gallagher, M, B. Ffrench, R. Flavin, N. Gleeson, O'Riain, C, S. Cocchiglia, Varešlija, D, S. Charmsaz, Cocchiglia, S, Y. Huang, C. O'Brien, AbuSaadeh, F, Charmsaz, S, S. Selemidis, C.D. Spillane, Brooks, D A, L. Young, Gleeson, N, Young, L, M. Gallagher, Kashdan, E, D. Varešlija, S.A. O'Toole, Huang, Y, R.D. Brooks, O'Toole, S A, E. Kashdan, C. O'Riain, O'Brien, C   +87 more
core   +1 more source

Circulating Tumor Cell Clusters Are Frequently Detected in Women with Early-Stage Breast Cancer

, 2021
The clinical relevance of circulating tumor cell clusters (CTC-clusters) in breast cancer (BC) has been mostly studied using the CellSearch®, a marker-dependent method detecting only epithelial-enriched clusters. However, due to epithelial-to-mesenchymal
Vingiani, Andrea, Daidone, Maria Grazia, Di Cosimo, Serena, Martinetti, Antonia, Scaperrotta, Gianfranco, Carolina Reduzzi, Zhang, Youbin, Paolo D’Amico, D'Amico, Paolo, Depretto, Catherine, Folli, Secondo, Antonia Martinetti, Gianfranco Scaperrotta, Gerratana, Lorenzo, Serena Di Cosimo, Maria Grazia Daidone, Andrea Vingiani, Youbin Zhang, Lorenzo Gerratana, Secondo Folli, Rosita Motta, Catherine Depretto, Cappelletti, Vera, Vismara, Marta, Motta, Rosita, Giancarlo Pruneri, Massimo Cristofanilli, Marta Vismara, Pruneri, Giancarlo, Reduzzi, Carolina, Vera Cappelletti, Cristofanilli, Massimo   +31 more
core   +2 more sources

Prognostic value of integrating circulating tumour cells and cell-free DNA in non-small cell lung cancer

Heliyon, 2022
Background: Non-small cell lung cancer (NSCLC) often presents at an incurable stage, and majority of patients will be considered for palliative treatment at some point in their disease.
Joanna Kapeleris, Juliana Müller Bark, Shanon Ranjit, Darryl Irwin, Gunter Hartel, Majid Ebrahimi Warkiani, Paul Leo, Connor O'Leary, Rahul Ladwa, Kenneth O'Byrne, Brett G.M. Hughes, Chamindie Punyadeera   +11 more
doaj   +1 more source

Longitudinal enumeration and cluster evaluation of circulating tumor cells improve prognostication for patients with newly diagnosed metastatic breast cancer in a prospective observational trial

Breast Cancer Research, 2018
Background Circulating tumor cells (CTCs) carry independent prognostic information in patients with metastatic breast cancer (MBC) on different lines of therapy.
Anna-Maria Larsson, Sara Jansson, Pär-Ola Bendahl, Charlotte Levin Tykjaer Jörgensen, Niklas Loman, Cecilia Graffman, Lotta Lundgren, Kristina Aaltonen, Lisa Rydén   +8 more
doaj   +1 more source